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- Antigen structure
- References [25]
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- Product number
- 13491-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13491-1-AP, RRID:AB_2097177
- Product name
- EGR2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EGR2 antibody (Cat. #13491-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references EGR2 affects mixed stroke repair through BNIP3L-mediated microglial mitophagy.
The Leupaxin/HDAC6/EGR2 axis facilitates breast cancer progression by enhancing macrophage M2 polarization.
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes.
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
RNA-Seq analysis of lymphocyte-specific gene expression patterns in IgG4-related disease: comparison of submandibular glands and peripheral blood.
Establishment of a SUMO pathway related gene signature for predicting prognosis, chemotherapy response and investigating the role of EGR2 in bladder cancer.
Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse.
Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice.
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
Chromatin Remodeling in Patient-Derived Colorectal Cancer Models.
Nicotine, THC, and Dolutegravir Modulate E-Cigarette-Induced Changes in Addiction- and Inflammation-Associated Genes in Rat Brains and Astrocytes.
Comprehensive Analysis of the Potential Immune-Related Biomarker ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After Photodynamic Therapy.
Development and Characterisation of an in vitro Model of Wallerian Degeneration.
Functional Characterization of Muscarinic Receptors in Human Schwann Cells.
M2 receptors activation modulates cell growth, migration and differentiation of rat Schwann-like adipose-derived stem cells.
MPGES-1 derived PGE2 inhibits cell migration by regulating ARP2/3 in the pathogenesis of Hirschsprung disease.
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
Characterization of neuromas in peripheral nerves and their effects on heterotopic bone formation.
LINC01939 inhibits the metastasis of gastric cancer by acting as a molecular sponge of miR-17-5p to regulate EGR2 expression.
RETRACTED: LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells.
Guanabenz Downregulates Inflammatory Responses via eIF2α Dependent and Independent Signaling.
Bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the C/EBP and PPARγ pathways.
The Lin28/let-7 axis is critical for myelination in the peripheral nervous system.
Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.
Early growth response 2 (Egr2) plays opposing roles in committing C3H10T1/2 stem cells to adipocytes and smooth muscle-like cells.
Zhang X, Zhang B, Shi C, Kampan N, Treebupachatsakul W, Pantan R, Narakornsak S, Phatsara M
IBRO neuroscience reports 2026 Jun;20:577-586
IBRO neuroscience reports 2026 Jun;20:577-586
The Leupaxin/HDAC6/EGR2 axis facilitates breast cancer progression by enhancing macrophage M2 polarization.
He S, Wang Q, He J, Chen Z, Xiao Y
Cell biology and toxicology 2025 Nov 25;41(1):154
Cell biology and toxicology 2025 Nov 25;41(1):154
Inhibition of Egr2 Protects against TAC-induced Heart Failure in Mice by Suppressing Inflammation and Apoptosis Via Targeting Acot1 in Cardiomyocytes.
Hou X, Hu G, Wang H, Yang Y, Sun Q, Bai X
Journal of cardiovascular translational research 2025 Jun;18(3):574-585
Journal of cardiovascular translational research 2025 Jun;18(3):574-585
Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity.
Li Y, You QL, Zhang SR, Huang WY, Zou WJ, Jie W, Li SJ, Liu JH, Lv CY, Cong J, Hu YY, Gao TM, Li JM
Molecular neurobiology 2025 Dec;62(12):15251-15266
Molecular neurobiology 2025 Dec;62(12):15251-15266
RNA-Seq analysis of lymphocyte-specific gene expression patterns in IgG4-related disease: comparison of submandibular glands and peripheral blood.
Tsuboi H, Honda F, Asashima H, Toko H, Kitada A, Abe S, Tanaka Y, Ohyama A, Yagishita M, Miki H, Hagiwara S, Kondo Y, Matsumoto I, Sumida T
Modern rheumatology 2025 Dec 22;36(1):122-131
Modern rheumatology 2025 Dec 22;36(1):122-131
Establishment of a SUMO pathway related gene signature for predicting prognosis, chemotherapy response and investigating the role of EGR2 in bladder cancer.
Xiao H, Huang X, Chen H, Zheng Y, Liu W, Chen J, Wei R, Lin M, Wang Q, Zhuang W
Journal of Cancer 2024;15(12):3841-3856
Journal of Cancer 2024;15(12):3841-3856
Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse.
Jin X, Xu H, Hu Q, Yin Y, Qin M, Xia Z
Histochemistry and cell biology 2024 Feb;161(2):195-205
Histochemistry and cell biology 2024 Feb;161(2):195-205
Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice.
Chen Y, Shang T, Sun J, Ji Y, Gong L, Li A, Ding F, Shen M, Zhang Q
The European journal of neuroscience 2024 Aug;60(4):4503-4517
The European journal of neuroscience 2024 Aug;60(4):4503-4517
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
Zheng JH, Zhu YH, Yang J, Ji PX, Zhao RK, Duan ZH, Yao HF, Jia QY, Yin YF, Hu LP, Li Q, Jiang SH, Huo YM, Liu W, Sun YW, Liu DJ
Cell reports 2024 Aug 27;43(8):114633
Cell reports 2024 Aug 27;43(8):114633
Chromatin Remodeling in Patient-Derived Colorectal Cancer Models.
Xiang K, Wang E, Mantyh J, Rupprecht G, Negrete M, Sanati G, Hsu C, Randon P, Dohlman A, Kretzschmar K, Bose S, Giroux N, Ding S, Wang L, Balcazar JP, Huang Q, Sundaramoorthy P, Xi R, McCall SJ, Wang Z, Jiang C, Kang Y, Kopetz S, Crawford GE, Lipkin SM, Wang XF, Clevers H, Hsu D, Shen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2303379
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2303379
Nicotine, THC, and Dolutegravir Modulate E-Cigarette-Induced Changes in Addiction- and Inflammation-Associated Genes in Rat Brains and Astrocytes.
Kulbe JR, Nguyen L, Le AA, Laird AE, Taffe MA, Nguyen JD, Fields JA
Brain sciences 2023 Nov 7;13(11)
Brain sciences 2023 Nov 7;13(11)
Comprehensive Analysis of the Potential Immune-Related Biomarker ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After Photodynamic Therapy.
Zhang ZJ, Wang KP, Huang YP, Jin C, Jiang H, Xiong L, Chen ZY, Wen Y, Liu ZT, Mo JG
Frontiers in pharmacology 2022;13:857774
Frontiers in pharmacology 2022;13:857774
Development and Characterisation of an in vitro Model of Wallerian Degeneration.
Elsayed H, Faroni A, Ashraf MR, Osuji J, Wunderley L, Zhang L, Elsobky H, Mansour M, Zidan AS, Reid AJ
Frontiers in bioengineering and biotechnology 2020;8:784
Frontiers in bioengineering and biotechnology 2020;8:784
Functional Characterization of Muscarinic Receptors in Human Schwann Cells.
Piovesana R, Faroni A, Tata AM, Reid AJ
International journal of molecular sciences 2020 Sep 11;21(18)
International journal of molecular sciences 2020 Sep 11;21(18)
M2 receptors activation modulates cell growth, migration and differentiation of rat Schwann-like adipose-derived stem cells.
Piovesana R, Faroni A, Magnaghi V, Reid AJ, Tata AM
Cell death discovery 2019;5:92
Cell death discovery 2019;5:92
MPGES-1 derived PGE2 inhibits cell migration by regulating ARP2/3 in the pathogenesis of Hirschsprung disease.
Wu F, Wen Z, Zhi Z, Li Y, Zhou L, Li H, Xu X, Tang W
Journal of pediatric surgery 2019 Oct;54(10):2032-2037
Journal of pediatric surgery 2019 Oct;54(10):2032-2037
Sericin Nerve Guidance Conduit Delivering Therapeutically Repurposed Clobetasol for Functional and Structural Regeneration of Transected Peripheral Nerves.
Zhang L, Yang W, Xie H, Wang H, Wang J, Su Q, Li X, Song Y, Wang G, Wang L, Wang Z
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
ACS biomaterials science & engineering 2019 Mar 11;5(3):1426-1439
Characterization of neuromas in peripheral nerves and their effects on heterotopic bone formation.
Minarelli J, Davis EL, Dickerson A, Moore WC, Mejia JA, Gugala Z, Olmsted-Davis EA, Davis AR
Molecular pain 2019 Jan-Dec;15:1744806919838191
Molecular pain 2019 Jan-Dec;15:1744806919838191
LINC01939 inhibits the metastasis of gastric cancer by acting as a molecular sponge of miR-17-5p to regulate EGR2 expression.
Chen M, Fan L, Zhang SM, Li Y, Chen P, Peng X, Liu DB, Ma C, Zhang WJ, Zou ZW, Li PD
Cell death & disease 2019 Jan 25;10(2):70
Cell death & disease 2019 Jan 25;10(2):70
RETRACTED: LncRNA-AF113014 promotes the expression of Egr2 by interaction with miR-20a to inhibit proliferation of hepatocellular carcinoma cells.
Zeng T, Wang D, Chen J, Tian Y, Cai X, Peng H, Zhu L, Huang A, Tang H
PloS one 2017;12(5):e0177843
PloS one 2017;12(5):e0177843
Guanabenz Downregulates Inflammatory Responses via eIF2α Dependent and Independent Signaling.
Takigawa S, Chen A, Nishimura A, Liu S, Li BY, Sudo A, Yokota H, Hamamura K
International journal of molecular sciences 2016 May 5;17(5)
International journal of molecular sciences 2016 May 5;17(5)
Bidens pilosa and its active compound inhibit adipogenesis and lipid accumulation via down-modulation of the C/EBP and PPARγ pathways.
Liang YC, Yang MT, Lin CJ, Chang CL, Yang WC
Scientific reports 2016 Apr 11;6:24285
Scientific reports 2016 Apr 11;6:24285
The Lin28/let-7 axis is critical for myelination in the peripheral nervous system.
Gökbuget D, Pereira JA, Bachofner S, Marchais A, Ciaudo C, Stoffel M, Schulte JH, Suter U
Nature communications 2015 Oct 14;6:8584
Nature communications 2015 Oct 14;6:8584
Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.
Ogawa M, Okamura T, Ishikura S, Doi K, Matsuzaki H, Tanaka Y, Ota T, Hayakawa K, Suzuki H, Tsunoda T, Sasazuki T, Shirasawa S
PloS one 2013;8(10):e76254
PloS one 2013;8(10):e76254
Early growth response 2 (Egr2) plays opposing roles in committing C3H10T1/2 stem cells to adipocytes and smooth muscle-like cells.
Wang SS, Huang HY, Chen SZ, Li X, Liu Y, Zhang WT, Tang QQ
The international journal of biochemistry & cell biology 2013 Aug;45(8):1825-32
The international journal of biochemistry & cell biology 2013 Aug;45(8):1825-32
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EGR2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EGR2. This antibody recognizes human, mouse, rat antigen. The EGR2 antibody has been validated for the following applications: ELISA, WB analysis.
