orb131906

antibody from Biorbyt
Targeting: EGR2 KROX20
Provider product page for orb131906
Western blot
Immunoprecipitation
Chromatin Immunoprecipitation

Antibody data

Product number
orb131906 - Provider product page
Provider
Biorbyt
Product name
EGR2 (C) Antibody, Rabbit Polyclonal
Antibody type
Polyclonal
Description
Rabbit polyclonal to EGR2. E3 SUMO-protein ligase EGR2 belongs to the EGR C2H2-type zinc-finger protein family. EGR2 is a sequence-specific DNA-binding transcription factor and binds to two specific DNA sites located in the promoter region of HOXA4. EGR2 helps SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in EGR2 are a cause of congenital hypomyelination neuropathy (CHN), of Charcot-Marie-Tooth disease type 1D (CMT1D), and of Dejerine-Sottas syndrome (DSS).
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Vial size
100 ul
Concentration
100 μg/ml BSA
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
EGR2 protein structure - orb131906 shown in red.