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- References [21]
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- Immunohistochemistry [1]
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- Product number
- 11705-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11705-1-AP, RRID:AB_2077302
- Product name
- CDK9 antibody
- Antibody type
- Polyclonal
- Description
- CDK9 antibody (Cat. #11705-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tumor-Resident Streptococcus pneumoniae Promotes Malignant Progression and Pazopanib Resistance in Clear Cell Renal Cell Carcinoma.
Pseudouridylation of 7SK by PUS7 regulates Pol II transcription elongation.
FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells.
Deciphering transcription activity of mammalian early embryos unveils on/off of zygotic genome activation by protein translation/degradation.
CircFUNDC1 interacts with CDK9 to promote mitophagy in nucleus pulposus cells under oxidative stress and ameliorates intervertebral disc degeneration.
The CDK9-targeting degrader PO-8 alleviates LPS-induced inflammation by inhibiting JAK-STAT signaling in vitro and in vivo.
Protein arginine methyltransferase 1 stimulates basal cell proliferation and migration to maintain corneal epithelial homeostasis.
Sclareol improves the pathology of Alzheimer's disease by inhibiting microglial inflammation via interacting with CDK9.
IGF2BP3 recruits NUDT21 to regulate SPTBN1 alternative polyadenylation and drive ovarian cancer progression.
Integrating cryo-OrbiSIMS with computational modelling and metadynamics simulations enhances RNA structure prediction at atomic resolution.
Inherited blood cancer predisposition through altered transcription elongation.
Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model.
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
DNA framework-engineered chimeras platform enables selectively targeted protein degradation.
Antinuclear antibodies in individuals with COVID-19 reflect underlying disease: Identification of new autoantibodies in systemic sclerosis (CDK9) and malignancy (RNF20, RCC1, TRIP13).
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression.
A Simplified Thermal Proteome Profiling Approach to Screen Protein Targets of a Ligand.
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents.
Wang J, Nan Y, Liu Q, Ding T, Liu D, Duo L, Zhao J, Gao S, Zhang Y, Dai Z, Yan S, Zhang W, Li Z, Liu W, Han B, Zhao Y, Yu Y, Zhao E, Li X, You B
Cancer research 2026 May 4;86(9):2237-2252
Cancer research 2026 May 4;86(9):2237-2252
Pseudouridylation of 7SK by PUS7 regulates Pol II transcription elongation.
Zhao Y, Sun HL, Li W, Ye C, Dou X, Peng Y, Wu T, Wang P, Ju CW, Liu S, Zhong Y, Dai Q, Pajdzik K, He C
Nature communications 2025 Oct 30;16(1):9595
Nature communications 2025 Oct 30;16(1):9595
FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells.
Gibaut QMR, Li C, Cheng A, Moranguinho I, Mori LP, Valente ST
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102525
Molecular therapy. Nucleic acids 2025 Jun 10;36(2):102525
Deciphering transcription activity of mammalian early embryos unveils on/off of zygotic genome activation by protein translation/degradation.
Zhang YR, Guo SM, Shi XY, Ding YW, Li HB, Li L, Xu JW, He X, Ma BX, Yin Y, Zhou LQ
Cell reports 2025 Jan 28;44(1):115215
Cell reports 2025 Jan 28;44(1):115215
CircFUNDC1 interacts with CDK9 to promote mitophagy in nucleus pulposus cells under oxidative stress and ameliorates intervertebral disc degeneration.
Gu T, He Y, Zhou J, Qiu X, Yang W, Zhu Q, Liang Y, Zheng Y, Yik JHN, Haudenschild DR, Fan S, Liu C, Shi W, Yao S, Ni W, Hu Z
Cell death & disease 2025 Feb 13;16(1):94
Cell death & disease 2025 Feb 13;16(1):94
The CDK9-targeting degrader PO-8 alleviates LPS-induced inflammation by inhibiting JAK-STAT signaling in vitro and in vivo.
Ao MT, Wang XM, Cao Y, Li XD, Zhang YX, Li JY, Li MY, Huang MX, Qiu YK, Hu HY, Wang LJ, Fang H, Li BC, Fang MJ
Biochemical pharmacology 2025 Dec;242(Pt 3):117341
Biochemical pharmacology 2025 Dec;242(Pt 3):117341
Protein arginine methyltransferase 1 stimulates basal cell proliferation and migration to maintain corneal epithelial homeostasis.
Yang J, Hu M, Yang M, Ni H, Zhou J, Li D, Ran J, Liu M
Cell death discovery 2025 Aug 15;11(1):385
Cell death discovery 2025 Aug 15;11(1):385
Sclareol improves the pathology of Alzheimer's disease by inhibiting microglial inflammation via interacting with CDK9.
Tang H, Li L, Yu Q, Chen L, Xu X, Meng Z, Zeng Y, Chen F, Muzaffar H, Wang W, Zhao X, Liang G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156504
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156504
IGF2BP3 recruits NUDT21 to regulate SPTBN1 alternative polyadenylation and drive ovarian cancer progression.
Luo X, Xie L, Ma X, Chen N, Xu J, Jiang X, Liu X, Yang Y, Liu T, Yi P, Xu J
Communications biology 2025 Apr 29;8(1):680
Communications biology 2025 Apr 29;8(1):680
Integrating cryo-OrbiSIMS with computational modelling and metadynamics simulations enhances RNA structure prediction at atomic resolution.
Ward S, Childs A, Staley C, Waugh C, Watts JA, Kotowska AM, Bhosale R, Borkar AN
Nature communications 2024 May 22;15(1):4367
Nature communications 2024 May 22;15(1):4367
Inherited blood cancer predisposition through altered transcription elongation.
Zhao J, Cato LD, Arora UP, Bao EL, Bryant SC, Williams N, Jia Y, Goldman SR, Nangalia J, Erb MA, Vos SM, Armstrong SA, Sankaran VG
Cell 2024 Feb 1;187(3):642-658.e19
Cell 2024 Feb 1;187(3):642-658.e19
Cartilage stem/progenitor cells-derived exosomes facilitate knee cartilage repair in a subacute osteoarthritis rat model.
Chen J, Ni X, Yang J, Yang H, Liu X, Chen M, Sun C, Wang Y
Journal of cellular and molecular medicine 2024 Apr;28(8):e18327
Journal of cellular and molecular medicine 2024 Apr;28(8):e18327
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
Zhou X, Liu C, Xia D
Clinical and experimental pharmacology & physiology 2023 Jul;50(7):541-553
Clinical and experimental pharmacology & physiology 2023 Jul;50(7):541-553
DNA framework-engineered chimeras platform enables selectively targeted protein degradation.
Zhou L, Yu B, Gao M, Chen R, Li Z, Gu Y, Bian J, Ma Y
Nature communications 2023 Jul 27;14(1):4510
Nature communications 2023 Jul 27;14(1):4510
Antinuclear antibodies in individuals with COVID-19 reflect underlying disease: Identification of new autoantibodies in systemic sclerosis (CDK9) and malignancy (RNF20, RCC1, TRIP13).
Bossuyt X, Vulsteke JB, Van Elslande J, Boon L, Wuyts G, Willebrords S, Frans G, Geukens N, Carpentier S, Tejpar S, Wildiers H, Blockmans D, De Langhe E, Vermeersch P, Derua R
Autoimmunity reviews 2023 Apr;22(4):103288
Autoimmunity reviews 2023 Apr;22(4):103288
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Li X, Ding K, Li X, Yuan B, Wang Y, Yao Z, Wang S, Huang H, Xu B, Xie L, Deng T, Chen XW, Chen Z
Nature communications 2022 Aug 4;13(1):4549
Nature communications 2022 Aug 4;13(1):4549
CSN6 promotes melanoma proliferation and metastasis by controlling the UBR5-mediated ubiquitination and degradation of CDK9.
Zhang Y, Hou J, Shi S, Du J, Liu Y, Huang P, Li Q, Liu L, Hu H, Ji Y, Guo L, Shi Y, Liu Y, Cui H
Cell death & disease 2021 Jan 22;12(1):118
Cell death & disease 2021 Jan 22;12(1):118
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression.
Li X, Yuan B, Lu M, Wang Y, Ding N, Liu C, Gao M, Yao Z, Zhang S, Zhao Y, Xie L, Chen Z
Nature communications 2021 Dec 10;12(1):7213
Nature communications 2021 Dec 10;12(1):7213
A Simplified Thermal Proteome Profiling Approach to Screen Protein Targets of a Ligand.
Zhang X, Ruan C, Zhu H, Li K, Zhang W, Wang K, Hu L, Ye M
Proteomics 2020 Aug;20(15-16):e1900372
Proteomics 2020 Aug;20(15-16):e1900372
Menin enhances c-Myc-mediated transcription to promote cancer progression.
Wu G, Yuan M, Shen S, Ma X, Fang J, Zhu L, Sun L, Liu Z, He X, Huang D, Li T, Li C, Wu J, Hu X, Li Z, Song L, Qu K, Zhang H, Gao P
Nature communications 2017 May 5;8:15278
Nature communications 2017 May 5;8:15278
Synthesis, structure-activity relationship studies and biological evaluation of novel 2,5-disubstituted indole derivatives as anticancer agents.
Hu H, Wu J, Ao M, Wang H, Zhou T, Xue Y, Qiu Y, Fang M, Wu Z
Chemical biology & drug design 2016 Nov;88(5):766-778
Chemical biology & drug design 2016 Nov;88(5):766-778
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 11705-1-AP(CDK9 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CDK9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CDK9. This antibody recognizes human,mouse,rat antigen. The CDK9 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
