ABIN116944

antibody from antibodies-online

Targeting: CDK9 C-2k, CDC2L4, PITALRE, TAK

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN116944

Provider

antibodies-online

Product name

anti-Cyclin-Dependent Kinase 9 (CDK9) (C-Term), (N-Term) antibody

Antibody type

Polyclonal

Antigen

Multiple synthetic peptides corresponding to C-terminal and N-terminal domains of the protein coded by the Human gene cdk9 (PITALRE). Remarks: The Murine cDNA is shown to be 98% identical with Human.

Description

This product was prepared from monospecific antiserum by Delipidation and Defibrination

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term,N-Term

Vial size

0.1 mL

Concentration

75 mg/mL (by Refractometry)

Storage

Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 2-8°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

[Interferon alfa 2b treatment decreases histological activity in children with chronic hepatitis B].

Castañeda C, García E, Grá B, Nodarse-Cuní H, García W, Andrade M, Martínez G, Trujillo M, Soto G, Amoroto M, Viada C, López-Saura P
Acta gastroenterologica Latinoamericana 2002 May;32(1):35-42

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The ability of positive transcription elongation factor B to transactivate human immunodeficiency virus transcription depends on a functional kinase domain, cyclin T1, and Tat.

Fujinaga K, Cujec TP, Peng J, Garriga J, Price DH, Graña X, Peterlin BM
Journal of virology 1998 Sep;72(9):7154-9

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Increased P-glycoprotein messenger RNA stability in rat liver tumors in vivo.

Lee CH, Bradley G, Ling V
Journal of cellular physiology 1998 Oct;177(1):1-12

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Cloning of murine CDK9/PITALRE and its tissue-specific expression in development.

Bagella L, MacLachlan TK, Buono RJ, Pisano MM, Giordano A, De Luca A
Journal of cellular physiology 1998 Nov;177(2):206-13

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Binding of CDK9 to TRAF2.

MacLachlan TK, Sang N, De Luca A, Puri PL, Levrero M, Giordano A
Journal of cellular biochemistry 1998 Dec 15;71(4):467-78

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Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer.

Bullrich F, MacLachlan TK, Sang N, Druck T, Veronese ML, Allen SL, Chiorazzi N, Koff A, Heubner K, Croce CM
Cancer research 1995 Mar 15;55(6):1199-205

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PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro.

Graña X, De Luca A, Sang N, Fu Y, Claudio PP, Rosenblatt J, Morgan DO, Giordano A
Proceedings of the National Academy of Sciences of the United States of America 1994 Apr 26;91(9):3834-8