12770-1-AP

antibody from Proteintech Group

Targeting: HNRNPD AUF1, HNRPD

Provider product page for 12770-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [13]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]
Immunohistochemistry [2]

Submit

Product number: 12770-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#12770-1-AP, RRID:AB_2117318
Product name: HNRNPD antibody
Antibody type: Polyclonal
Description: KD/KO validated HNRNPD antibody (Cat. #12770-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

HNRNPD protein structure - 12770-1-AP shown in red.

Submitted references Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.

Wang C, Huang H
Biochemical and biophysical research communications 2021 Nov 19;579:181-187

Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.

Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, Chen Z, Yin X, Sun C, Mao Y, Zhou F, Shao Y, Liu Q, Xu J, Cheng L, Yu D, Li P, Yi P, He J, Geng G, Guo Q, Si Y, Zhao H, Li H, Banes GL, Liu H, Nakamura Y, Kurita R, Huang Y, Wang X, Wang F, Fang G, Engel JD, Shi L, Zhang YE, Yu J
Developmental cell 2021 Feb 22;56(4):478-493.e11

hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.

Akinyemi AR, Li D, Zhang J, Liu Q
Neuroscience letters 2021 Apr 23;751:135824

Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates.

Aarum J, Cabrera CP, Jones TA, Rajendran S, Adiutori R, Giovannoni G, Barnes MR, Malaspina A, Sheer D
EMBO reports 2020 Oct 5;21(10):e49585

A Comparative Quantitative Proteomic Analysis of HCMV-Infected Cells Highlights pUL138 as a Multifunctional Protein.

Li Y, Shang W, Xiao G, Zhang LK, Zheng C
Molecules (Basel, Switzerland) 2020 May 28;25(11)

lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.

Liu C, Peng Z, Li P, Fu H, Feng J, Zhang Y, Liu T, Liu Y, Liu Q, Liu Q, Li D, Wu M
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208

Angiotensin II contributes to intratumoral immunosuppressionvia induction of PD-L1 expression in non-small cell lung carcinoma.

Yang K, Zhou J, Chen Y, Chen Y, Chen L, Zhang P, Ma L, Jiang Z, Bian J, Yin W
International immunopharmacology 2020 Jul;84:106507

Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.

Bai Y, Wang J, Gao Z, Dai E
Pathology oncology research : POR 2020 Apr;26(2):967-976

Acetylation of Cytidine in mRNA Promotes Translation Efficiency.

Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, Fox SD, Zengeya TT, Andresson T, Meier JL, Coller J, Oberdoerffer S
Cell 2018 Dec 13;175(7):1872-1886.e24

Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis.

Dai P, Wang Q, Wang W, Jing R, Wang W, Wang F, Azadzoi KM, Yang JH, Yan Z
International journal of molecular sciences 2016 Jan 21;17(1)

Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection.

Chai F, Li HY, Wang W, Zhu XJ, Li Y, Wang S, Guo L, Zhang LK, Xiao G
Biochimica et biophysica acta 2015 Aug;1854(8):967-78

Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.

Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM, Shaw PJ
Brain : a journal of neurology 2014 Jul;137(Pt 7):2040-51

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Neumann M, Valori CF, Ansorge O, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ishihara K, Ang LC, Bilbao JM, Mackenzie IR
Acta neuropathologica 2012 Nov;124(5):705-16

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 12770-1-AP(HNRNPD antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using HNRNPD antibody 12770-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human cervical cancer using 12770-1-AP(HNRNPD antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human cervical cancer using 12770-1-AP(HNRNPD antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue