Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13886-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13886-1-AP, RRID:AB_10643374
- Product name
- SIAH1 antibody
- Antibody type
- Polyclonal
- Description
- SIAH1 antibody (Cat. #13886-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TSG101 Promotes SIAH1 Auto-Ubiquitination to Drive Migration and Invasion in Hepatocellular Carcinoma Cells.
XPNPEP2 regulates angiogenesis via modulation of mitochondrial function through SLC25A6.
The E3 ubiquitin ligase SIAH1 targets a bacterial pore-forming toxin to facilitate xenophagy.
Phase separation of ERCC6L2-CtIP regulates the extent of DNA end resection.
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Qiu J, Gu X, Wu K, Wu J, Xu C, Shan W, Shi H
Journal of cellular and molecular medicine 2026 Mar;30(6):e71109
Journal of cellular and molecular medicine 2026 Mar;30(6):e71109
XPNPEP2 regulates angiogenesis via modulation of mitochondrial function through SLC25A6.
Yang C, Lu Y, Xia Y, Wang B, Xu J, Zhang Y, Yan J, Liu M, Chen T, Zhao X, Cang X, Mao J, Jiang P
Frontiers in cell and developmental biology 2025;13:1698651
Frontiers in cell and developmental biology 2025;13:1698651
The E3 ubiquitin ligase SIAH1 targets a bacterial pore-forming toxin to facilitate xenophagy.
Wu M, Hu X, Iibushi J, Murase K, Nozawa T, Nakagawa I
Cell reports 2025 Sep 23;44(9):116257
Cell reports 2025 Sep 23;44(9):116257
Phase separation of ERCC6L2-CtIP regulates the extent of DNA end resection.
Yin Y, Lin J, Cai X, Nie R, Lin J, Li S, Xiang Z, Ling Y, Zhang Y, Zhou J, Chen J, Lin W, Duan J, Zheng X, Xie D, Cai M
Nature cell biology 2025 Oct;27(10):1771-1784
Nature cell biology 2025 Oct;27(10):1771-1784
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
Zhang C, Liu Z, Wang X, Zhang B, Cui L, Hu Q, Hu B, Cao K, Shan W, Shi H, Wang R
iScience 2023 Jun 16;26(6):106852
iScience 2023 Jun 16;26(6):106852
GABA induced by sleep deprivation promotes the proliferation and migration of colon tumors through miR-223-3p endogenous pathway and exosome pathway.
Bao H, Peng Z, Cheng X, Jian C, Li X, Shi Y, Zhu W, Hu Y, Jiang M, Song J, Fang F, Chen J, Shu X
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Journal of experimental & clinical cancer research : CR 2023 Dec 18;42(1):344
Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.
Liu Y, Li Q, Geng L, Zhou X, Zhou X, Dong Y, Zhang Y
Experimental cell research 2022 Oct 1;419(1):113305
Experimental cell research 2022 Oct 1;419(1):113305
Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis.
Zeng Y, Qiu R, Yang Y, Gao T, Zheng Y, Huang W, Gao J, Zhang K, Liu R, Wang S, Hou Y, Yu W, Leng S, Feng D, Liu W, Zhang X, Wang Y
Cell reports 2019 Nov 5;29(6):1482-1498.e4
Cell reports 2019 Nov 5;29(6):1482-1498.e4
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The SIAH1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SIAH1. This antibody recognizes human, mouse antigen. The SIAH1 antibody has been validated for the following applications: ELISA, WB analysis.