Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB10383 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB10383, RRID:AB_1713964
- Product name
- SIAH1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SIAH1.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins.
p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1.
Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway.
Hu G, Fearon ER
Molecular and cellular biology 1999 Jan;19(1):724-32
Molecular and cellular biology 1999 Jan;19(1):724-32
p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1.
Matsuzawa S, Takayama S, Froesch BA, Zapata JM, Reed JC
The EMBO journal 1998 May 15;17(10):2736-47
The EMBO journal 1998 May 15;17(10):2736-47
Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway.
Hu G, Zhang S, Vidal M, Baer JL, Xu T, Fearon ER
Genes & development 1997 Oct 15;11(20):2701-14
Genes & development 1997 Oct 15;11(20):2701-14
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot using SIAH1 polyclonal antibody (Cat # PAB10383) at 1 ug/mL on human brain lysate (20 ug/lane).