APR03858G
antibody from Leading Biology
Targeting: IL13
ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- APR03858G - Provider product page
- Provider
- Leading Biology
- Product name
- IL13 Antibody (C-term)
- Antibody type
- Polyclonal
- Description
- This gene encodes an immunoregulatory cytokine producedprimarily by activated Th2 cells. This cytokine is involved inseveral stages of B-cell maturation and differentiation. Itup-regulates CD23 and MHC class II expression, and promotes IgEisotype switching of B cells. This cytokine down-regulatesmacrophage activity, thereby inhibits the production ofpro-inflammatory cytokines and chemokines. This cytokine is foundto be critical to the pathogenesis of allergen-induced asthma butoperates through mechanisms independent of IgE and eosinophils.This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster onchromosome 5q, with this gene particularly close to IL4. [providedby RefSeq].
- Reactivity
- Human
- Host
- Rabbit
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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