Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF-204-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-4 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-4 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse IL-4 and recombinant rat IL-4 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Thymic stromal lymphopoietin from trophoblasts induces dendritic cell-mediated regulatory TH2 bias in the decidua during early gestation in humans.
IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.
Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue.
Peripheral expansion of circulating T-helper 1 cells predicts coronary endothelial dysfunction after cardiac transplantation.
Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression.
T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta.
T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta.
Guo PF, Du MR, Wu HX, Lin Y, Jin LP, Li DJ
Blood 2010 Sep 23;116(12):2061-9
Blood 2010 Sep 23;116(12):2061-9
IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.
Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK
Immunology letters 2010 Jan 4;127(2):150-6
Immunology letters 2010 Jan 4;127(2):150-6
Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
European journal of immunology 2008 Apr;38(4):1012-23
European journal of immunology 2008 Apr;38(4):1012-23
T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue.
Withers DR, Fiorini C, Fischer RT, Ettinger R, Lipsky PE, Grammer AC
Blood 2007 Jun 1;109(11):4856-64
Blood 2007 Jun 1;109(11):4856-64
Peripheral expansion of circulating T-helper 1 cells predicts coronary endothelial dysfunction after cardiac transplantation.
Methe H, Wiegand D, Welsch U, Krombach F, Meiser B, Nabauer M, Koglin J
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 Jul;24(7):833-40
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005 Jul;24(7):833-40
Suppressive properties of human CD4+CD25+ regulatory T cells are dependent on CTLA-4 expression.
Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, Beauplet A, Robillard N, Semana G
European journal of immunology 2004 Dec;34(12):3485-96
European journal of immunology 2004 Dec;34(12):3485-96
T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta.
Hakonarson H, Whelan R, Leiter J, Kim C, Chen M, Campbell D, Grunstein MM
The Journal of allergy and clinical immunology 2002 Oct;110(4):624-33
The Journal of allergy and clinical immunology 2002 Oct;110(4):624-33
T lymphocyte-mediated changes in airway smooth muscle responsiveness are attributed to induced autocrine release and actions of IL-5 and IL-1beta.
Hakonarson H, Whelan R, Leiter J, Kim C, Chen M, Campbell D, Grunstein MM
The Journal of allergy and clinical immunology 2002 Oct;110(4):624-33
The Journal of allergy and clinical immunology 2002 Oct;110(4):624-33
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by IL-4 and Neutralization by Human IL-4 Antibody. Cell Proliferation Induced by IL-4 and Neutralization by Human IL-4 Antibody.