Antibody data
- Antibody Data
- Antigen structure
- References [93]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- 66142-1-Ig - Provider product page

- Provider
- Proteintech Group
- Product name
- IL-4 antibody
- Antibody type
- Monoclonal
- Description
- IL-4 antibody (Cat. #66142-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G2C5
- Vial size
- 20ul, 150ul
Submitted references Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
Modular alginate-based hydrogels embedding multilayer nanofibers: A synergistic strategy for hemostasis, antibacterial, and immunomodulatory therapy.
Synergistic disruption of the blood-brain barrier in tree shrews by Methamphetamine and HIV-1 Tat via TRPM2-Mediated astrocyte inflammation.
Capsular Polysaccharide of Lactiplantibacillus plantarum DPUL F232 Alleviates Whey Protein Allergy by Regulating Immunity, Gut Microbiota, and Production of SCFAs.
Melatonin alleviates endoplasmic reticulum stress and its mediated inflammation in adipocytes via the PER1/ATF6 signal.
Adiponectin attenuates atherosclerosis via macrophage polarization-mediated T Cell exhaustion by modulating the NF-κB p65/PI3K/Akt signaling pathway.
TNFSF15 alleviates myeloid-derived suppressor cell-mediated cancer immunosuppression in mice.
Pediatric IPEX-Associated Dermatitis Responds To Dupilumab: Evidence from Skin Transcriptomics and Immune Profiling.
Saussurea involucrata oral liquid alleviates joint inflammation in CIA rats by modulating macrophage polarization and glucose metabolism.
Dual-targeted molybdenum nanomedicine treats acute pancreatitis by blocking mitochondrial DNA-triggered cGAS-STING signaling via ROS modulation.
Roles of Catecholamines and Inflammation in Endothelial Dysfunction: a Study Using Takotsubo Syndrome Patient-specific hiPSC-ECs.
CAR-M2 immunotherapy resolves renal fibrosis via revascularization and apoptosis of profibrotic Cxcr2(+) endothelial cells.
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells.
M2-type macrophage nanovesicles regulate the inflammatory response after necrotizing enterocolitis by inducing M1 to M2-like macrophage polarization.
Bacterial cellulose membrane integrating phase-transited lysozyme nanofilm loaded with biguanides for dressing treatment of atopic dermatitis.
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1-Mediated Transactivation of CD47.
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Preclinical study of engineering MSCs promoting diabetic wound healing and other inflammatory diseases through M2 polarization.
Adult Hymenolepis nana and its excretory-secretory products elicit mouse immune responses via tuft/IL-13 and FOXM1 signaling pathways.
Macrophage Changes and High-Throughput Sequencing in Aging Mouse Intervertebral Disks.
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway.
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Reductive Adjuvant Nanosystem for Alleviated Atopic Dermatitis Syndromes.
Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPβ in SAMP8 mice.
Prognostic value of LPAR1 expression and methylation in low-grade gliomas: a meta-analysis of TCGA and CGGA datasets and functional validation.
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma.
Deciphering the Proteomic Landscape of Circulating Extracellular Vesicles in Human Abdominal Aortic Aneurysm.
Targeting to Intensify M2 Macrophage Polarization Ameliorate Podocyte Lipid Accumulation and Damage by Tea Polyphenols via Activating SIRT1 in the Aged Model Rats With DKD.
Mannose-B from Codonopsis pilosula modulates LAMB1 expression to enhance trophoblast function and alleviate subchorionic hematoma.
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Nanomedicine Penetrating Blood-Pancreas Barrier for Effective Treatment of Acute Pancreatitis.
The Role and Mechanism of TRIM13 Regulation of TRAF6 Ubiquitination in the Synergy of Inflammatory Responses and Neurotoxicity Induced by METH and HIV- 1 Tat Protein in Astrocytes.
Emu oil alleviates atopic dermatitis-like responses by inhibiting Cdc42 signaling of keratinocyte.
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats.
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Increased S. aureus colonization and reduced antimicrobial peptide expression in erythrodermic psoriasis.
Cosentyx alleviates psoriasis-induced podocyte injury by inhibiting the tlr/nf-κb signaling pathway.
Marine bromophenols suppressed choroidal neovascularization by targeting HUWE1 through NF-κb signaling pathway.
Sodium-glucose co-transporter 2 inhibitor canagliflozin modulates myocardial metabolism and inflammation in a swine model for chronic myocardial ischemia.
Resatorvid (TAK-242) Ameliorates Ulcerative Colitis by Modulating Macrophage Polarization and T Helper Cell Balance via TLR4/JAK2/STAT3 Signaling Pathway.
CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice.
STAT6 blockade ameliorates thyroid function in Graves' disease via downregulation of the sodium/iodide symporter.
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization.
A Series of 35 Cutaneous Infections Caused by Mycobacterium marinum in Han Chinese Population.
Dupilumab improve acquired reactive perforating collagenosis characterized by type 2 inflammation.
Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model mice.
Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds.
The effect of acupuncture on lateral habenular nucleus and intestinal microflora in depression model rats.
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies.
Investigation of macrophage polarization in herniated nucleus pulposus of patients with lumbar intervertebral disc herniation.
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Induced Overexpression of B Cell-Activating Factor by Triiodothyronine Results in Abnormal B Cell Differentiation in Mice.
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Intrahepatic eosinophilic proliferative phlebitis in Japanese black cattle indicate allergies involving mast cell tryptase-dependent activation.
Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing.
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
IL-4 and CCR7 play an important role in the development of keloids in patients with a family history.
Intravenous AAV9 administration results in safe and widespread distribution of transgene in the brain of mini-pig.
Mesoporous silica nanoparticle-modified electrode arrays of cochlear implants for delivery of siRNA-TGFβ1 into the inner ear.
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia.
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Chitooligosaccharides alleviate hepatic fibrosis by regulating the polarization of M1 and M2 macrophages.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease.
Circular RNA circWWC3 augments breast cancer progression through promoting M2 macrophage polarization and tumor immune escape via regulating the expression and secretion of IL-4.
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D.
STAT6 up-regulation amplifies M2 macrophage anti-inflammatory capacity through mesenchymal stem cells.
Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis.
DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion.
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Neural stem cells induce M2 polarization of macrophages through the upregulation of interleukin-4.
Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic.
Macrophage polarization in human gingival tissue in response to periodontal disease.
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Pre-transplant infusion of donor-derived dendritic cells maintained at the immature stage by sinomenine increases splenic Foxp3(+) Tregs in recipient rats after renal allotransplantation.
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Lu Z, Zhou H, Tang H, Luo S, Wang J, Zheng X, Hu Y, Qin Q, Yang C, Mo S, Huang X, Tang L, Huang B, Xu W, Nong J, Gan G, Qin D, Peng Z, Jian C, Liu X, Li X, Shang J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
Modular alginate-based hydrogels embedding multilayer nanofibers: A synergistic strategy for hemostasis, antibacterial, and immunomodulatory therapy.
Liu H, Lv Y, Li J, Kang L, Chen M, Tan L, Yao X, Wang H, Zhang M, Li J, Zhu J, Zhang C, Yu J, Wu D
Carbohydrate polymers 2026 May 1;379:124977
Carbohydrate polymers 2026 May 1;379:124977
Synergistic disruption of the blood-brain barrier in tree shrews by Methamphetamine and HIV-1 Tat via TRPM2-Mediated astrocyte inflammation.
Teng HX, Huang J, Miao L, Yang X, Xu LS, Zhao YJ, Li J, Zeng XF
Brain, behavior, and immunity 2026 Mar 14;136:106538
Brain, behavior, and immunity 2026 Mar 14;136:106538
Capsular Polysaccharide of Lactiplantibacillus plantarum DPUL F232 Alleviates Whey Protein Allergy by Regulating Immunity, Gut Microbiota, and Production of SCFAs.
Feng L, Guo Z, Li X, Yao W, Mu G, Zhu X
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7499-7515
Journal of agricultural and food chemistry 2026 Mar 11;74(9):7499-7515
Melatonin alleviates endoplasmic reticulum stress and its mediated inflammation in adipocytes via the PER1/ATF6 signal.
Dang LP, Lv R, Zuo YF, Sun C
The international journal of biochemistry & cell biology 2026 Jan;190:106874
The international journal of biochemistry & cell biology 2026 Jan;190:106874
Adiponectin attenuates atherosclerosis via macrophage polarization-mediated T Cell exhaustion by modulating the NF-κB p65/PI3K/Akt signaling pathway.
Qin M, Xu S, Chen Y, Luo X, Tang X, Zhang L, Xu Q
Tissue & cell 2026 Feb;98:103150
Tissue & cell 2026 Feb;98:103150
TNFSF15 alleviates myeloid-derived suppressor cell-mediated cancer immunosuppression in mice.
Zhu YP, Sun J, Cao XY, Ding XY, Wang YY, Han QJ, Wang JY, Li LY, Zhang ZS
Acta pharmacologica Sinica 2026 Feb;47(2):493-503
Acta pharmacologica Sinica 2026 Feb;47(2):493-503
Pediatric IPEX-Associated Dermatitis Responds To Dupilumab: Evidence from Skin Transcriptomics and Immune Profiling.
Yang J, Li G, Zhang J, Wang J, Yang Y, Guo Q, Yan K, Hu H, Xue J, Ma Y, Liang J, Yao Z, Zhang H, Li C
Journal of clinical immunology 2026 Feb 7;46(1)
Journal of clinical immunology 2026 Feb 7;46(1)
Saussurea involucrata oral liquid alleviates joint inflammation in CIA rats by modulating macrophage polarization and glucose metabolism.
Maimaitituersun S, Mijiti W, Cong S, Zhao X, Zhou Z, Ji P, Luo L
BMC immunology 2026 Feb 3;27(1)
BMC immunology 2026 Feb 3;27(1)
Dual-targeted molybdenum nanomedicine treats acute pancreatitis by blocking mitochondrial DNA-triggered cGAS-STING signaling via ROS modulation.
Liu J, Wang D, Wang S, Shi X, Xiong T, Lu Y, Yang J, Wei W, Gong X, Huang Q, Ji L, Ai K
Journal of controlled release : official journal of the Controlled Release Society 2026 Feb 10;390:114549
Journal of controlled release : official journal of the Controlled Release Society 2026 Feb 10;390:114549
Roles of Catecholamines and Inflammation in Endothelial Dysfunction: a Study Using Takotsubo Syndrome Patient-specific hiPSC-ECs.
Yang G, Zhong L, Wang J, Yang C, Cyganek L, Hamdani N, Zhou X, Fan X, El-Battrawy I, Akin I
Stem cell reviews and reports 2026 Apr;22(3):1460-1476
Stem cell reviews and reports 2026 Apr;22(3):1460-1476
CAR-M2 immunotherapy resolves renal fibrosis via revascularization and apoptosis of profibrotic Cxcr2(+) endothelial cells.
Zhao W, Zhou X, Zhao X, Tian H, Su Y, Zhao S, Liu M, Zhang Q, Chen L, Li X, Liu D, Li J, Li L, Wang Y, Li X, Yan J, Chen W, Liu B, Zhu C, Zeng W
Cell reports. Medicine 2026 Apr 21;7(4):102698
Cell reports. Medicine 2026 Apr 21;7(4):102698
TGF-β-Smad2/3 signaling in high-altitude pulmonary hypertension in rats: Role and mechanisms via macrophage M2 polarization.
Ma W, Ma Y, Bai Y, Guo C, Zhang Q, Su X
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Open medicine (Warsaw, Poland) 2025;20(1):20251279
Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells.
Tang J, Hu Y, Fang J, Zhu W, Xu W, Yu D, Zheng Z, Zhou Q, Fu H, Zhang W
Drug design, development and therapy 2025;19:303-324
Drug design, development and therapy 2025;19:303-324
M2-type macrophage nanovesicles regulate the inflammatory response after necrotizing enterocolitis by inducing M1 to M2-like macrophage polarization.
Liu C, Gong J, Zhang L, Wang Y, Huang Y, Ju R
Frontiers in cellular and infection microbiology 2025;15:1664897
Frontiers in cellular and infection microbiology 2025;15:1664897
Bacterial cellulose membrane integrating phase-transited lysozyme nanofilm loaded with biguanides for dressing treatment of atopic dermatitis.
Lin J, Yu H, Huang Y, Yuan J, Wang C, Bai B
International journal of biological macromolecules 2025 Sep;323(Pt 1):147047
International journal of biological macromolecules 2025 Sep;323(Pt 1):147047
Phase-adapted metal ion supply for spinal cord repair with a Mg-Zn incorporated chimeric microsphere.
Liu X, Ma B, Hu S, Li D, Pan C, Xu Z, Chen H, Wang Y, Wang H
Biomaterials 2025 Sep;320:123253
Biomaterials 2025 Sep;320:123253
SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1-Mediated Transactivation of CD47.
Liu Z, Zhao X, Zang M, Yuan H, Qin X, Li X, Zhao S, Tan R, Yan K, Liu L, Fan Y, Zhang N, Shi B, Han B, Chen S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e04200
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e04200
Anemarrhena asphodeloides Bunge and Phellodendri Chinensis Cortex inhibits the PTGS2/EP2/cAMP/Epac1 signaling pathway to reduce microglial M1 polarization, thereby blocking chronic stress-induced depression-like behavior.
Zhao DP, Xue A, Yuan K, Zuo K, Li Y, Bian ZH, Xu HD, Cheng SM, Yang M, Zhao HM, Ma X, Lei X, Zhang N
Journal of ethnopharmacology 2025 May 12;347:119792
Journal of ethnopharmacology 2025 May 12;347:119792
Exploring the active components and potential mechanisms of Zhimu-Huangbai herb-pair in the treatment of depression.
Lei X, Zhao D, Chen T, Li Q, Xue A, Hu Z, Jia F, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Mar;138:156365
Preclinical study of engineering MSCs promoting diabetic wound healing and other inflammatory diseases through M2 polarization.
Wu D, Liu R, Cen X, Dong W, Chen Q, Lin J, Wang X, Ling Y, Mao R, Sun H, Huang R, Su H, Xu H, Qin D
Stem cell research & therapy 2025 Mar 5;16(1):113
Stem cell research & therapy 2025 Mar 5;16(1):113
Adult Hymenolepis nana and its excretory-secretory products elicit mouse immune responses via tuft/IL-13 and FOXM1 signaling pathways.
Mou R, Cui XY, Luo YS, Cheng Y, Luo QY, Zhang ZF, Wu WL, Li JF, Zhang K
Parasites & vectors 2025 Mar 11;18(1):100
Parasites & vectors 2025 Mar 11;18(1):100
Macrophage Changes and High-Throughput Sequencing in Aging Mouse Intervertebral Disks.
Wang W, Jiang C, Chen JH, Chen YL, Zhang ZW, Yang ZC, Li J, Li XC
JOR spine 2025 Jun;8(2):e70061
JOR spine 2025 Jun;8(2):e70061
Activation of GPER1 alleviates white matter injury by promoting microglia M2 polarization through EGFR/Stat3 pathway in intracerebral hemorrhage mice.
Zhang X, Mao J, Li H, Zhang C, Ge H, Zhong J
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 Jun;34(6):108315
Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway.
Liu Y, Li T, Niu C, Yuan Z, Sun S, Liu D
Molecular medicine (Cambridge, Mass.) 2025 Jan 3;31(1):1
Molecular medicine (Cambridge, Mass.) 2025 Jan 3;31(1):1
ZIP8 Regulates Inflammation and Macrophage Polarisation in Intervertebral Disc Degeneration via the Wnt/β-Catenin Pathway.
Xu J, Gu H, Zhou K, Wu L, Zhang Y, Bian C, Huang Z, Chen G, Cheng X, Yin X
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Journal of cellular and molecular medicine 2025 Feb;29(4):e70431
Reductive Adjuvant Nanosystem for Alleviated Atopic Dermatitis Syndromes.
Lu Y, Shan X, Huang J, Zhou H, Zhu Y, Wang S, Luo Z, Liu X, Guo X, Shi Y, Hu Y, Liu H, Zhang J, Huang P, Luo L, You J
ACS nano 2025 Feb 4;19(4):4195-4212
ACS nano 2025 Feb 4;19(4):4195-4212
Effects of electroacupuncture on microglia phenotype and epigenetic modulation of C/EBPβ in SAMP8 mice.
Wang L, Li W, Wu W, Liu Q, You M, Liu X, Ye C, Chen J, Tan Q, Liu G, Du Y
Brain research 2025 Feb 15;1849:149339
Brain research 2025 Feb 15;1849:149339
Prognostic value of LPAR1 expression and methylation in low-grade gliomas: a meta-analysis of TCGA and CGGA datasets and functional validation.
Chen H, Liang W, Li Z, Bian C, Wang H, Luo S, Xin Y, Feng W, Liang L
BMC cancer 2025 Dec 30;26(1):161
BMC cancer 2025 Dec 30;26(1):161
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Fan Y, Ge P, Wang X, Xu J, Wang J, Li H, Gu Q, Xie H, Lin Y, Lu Y, Wang C, Xie P, Hu Z
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Journal of nanobiotechnology 2025 Dec 29;24(1):101
A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma.
Qiu S, Ma L, Yu K, Xu X, Zhang X, Yu W, Wang K, Tian X, Miao Y, Wang Y, Guo W, Xue X, Cui J, Yu X, Kang R, Zhou Q, Yu Y, Tang D, Wang J
Developmental cell 2025 Dec 1;60(23):3321-3338.e12
Developmental cell 2025 Dec 1;60(23):3321-3338.e12
Deciphering the Proteomic Landscape of Circulating Extracellular Vesicles in Human Abdominal Aortic Aneurysm.
Yu C, Zhang G, Pei S, Zhang Y, Yuan P, Miao R, Kadier K, Zhang P, Gu T, Wu R, Zhang H, Zhang S, Yang B, Wu H, Xu Y, Hu K, Xu Q, Chen Y, Wang J, Cai Z, Tang J, Li T, Song Y
Journal of cellular and molecular medicine 2025 Aug;29(15):e70725
Journal of cellular and molecular medicine 2025 Aug;29(15):e70725
Targeting to Intensify M2 Macrophage Polarization Ameliorate Podocyte Lipid Accumulation and Damage by Tea Polyphenols via Activating SIRT1 in the Aged Model Rats With DKD.
Chen S, Wang X, Li C, Cheng L, Lv C, Xue L, Zhang C, Li X, Li M, Guo Q, Zhao Y, Zhao H
Food science & nutrition 2025 Aug;13(8):e70736
Food science & nutrition 2025 Aug;13(8):e70736
Mannose-B from Codonopsis pilosula modulates LAMB1 expression to enhance trophoblast function and alleviate subchorionic hematoma.
Sun Q, Gao Y, Asan K, Ji J, Xu J, Wu X, Ren J, Feng W, Song M, Wang S, Zhang B, Zhou Y, Han C, Liu S, Yang W
Scientific reports 2025 Aug 11;15(1):29297
Scientific reports 2025 Aug 11;15(1):29297
Autophagy Regulation Attenuates Neuroinflammation and Cognitive Decline in an Alzheimer's Disease Mouse Model with Chronic Cerebral Hypoperfusion.
Yang Q, Yang C, Lv H, Zheng X, Mao S, Liu N, Mo S, Liao B, Yang M, Lu Z, Tang L, Huang X, Jian C, Shang J
Inflammation 2025 Apr;48(2):541-556
Inflammation 2025 Apr;48(2):541-556
Nanomedicine Penetrating Blood-Pancreas Barrier for Effective Treatment of Acute Pancreatitis.
Wang D, Wang S, Liu J, Shi X, Xiong T, Li R, Wei W, Ji L, Huang Q, Gong X, Ai K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2413925
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Apr;12(13):e2413925
The Role and Mechanism of TRIM13 Regulation of TRAF6 Ubiquitination in the Synergy of Inflammatory Responses and Neurotoxicity Induced by METH and HIV- 1 Tat Protein in Astrocytes.
Tan Y, Miao L, Wang C, Wang H, Li Y, Huang Y, Teng H, Tian Y, Yang G, Zeng X, Li J
Neurotoxicity research 2025 Apr 7;43(2):21
Neurotoxicity research 2025 Apr 7;43(2):21
Emu oil alleviates atopic dermatitis-like responses by inhibiting Cdc42 signaling of keratinocyte.
Bu L, Wang M, Liu X, Zhang M, Zhang Y, Zhang X, Liang F, Huang B, Huang J, Wu S, Tang X, Wang X, Zhang L
International immunopharmacology 2024 Sep 30;139:112706
International immunopharmacology 2024 Sep 30;139:112706
IGF-1 inhibits inflammation and accelerates angiogenesis via Ras/PI3K/IKK/NF-κB signaling pathways to promote wound healing.
Zhang X, Hu F, Li J, Chen L, Mao YF, Li QB, Nie CY, Lin C, Xiao J
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Sep 1;200:106847
A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.
Wang Y, Chen Y, Zhou T, Li J, Zhang N, Liu N, Zhou P, Mao Y
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Journal of nanobiotechnology 2024 Nov 13;22(1):702
Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats.
Luo J, Liang C, Chen K, Zeng K, Bai R, Tang C, Li J, Nong X
BMC oral health 2024 Mar 20;24(1):356
BMC oral health 2024 Mar 20;24(1):356
[Aqueous extract of Chuan Xiong Rhizoma enhances inhibitory effect of temozolomide against brain metastasis of melanoma in mice].
Zhao Q, Zhang Z, Zhou X, Rong X, Liu X, Zhao X, Wang H, Pang J, Li S, Li X
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Jun 20;44(6):1088-1097
Myeloid-derived growth factor ameliorates dextran sodium sulfate-induced colitis by regulating macrophage polarization.
Yang Y, Zhao C, Yang Z, Du C, Chang Z, Wen X, Zhang X, Liu Y, Hu L, Gao Z
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Journal of molecular medicine (Berlin, Germany) 2024 Jul;102(7):875-886
Increased S. aureus colonization and reduced antimicrobial peptide expression in erythrodermic psoriasis.
Liu Y, Wu X, Song P, Liu L, Zhong X, He Q, Zhang Z
International immunopharmacology 2024 Jan 25;127:111343
International immunopharmacology 2024 Jan 25;127:111343
Cosentyx alleviates psoriasis-induced podocyte injury by inhibiting the tlr/nf-κb signaling pathway.
Aixue W, Feng W, Huanhuan Z, Xixing M, Yanling L
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Feb;30(2):e13562
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2024 Feb;30(2):e13562
Marine bromophenols suppressed choroidal neovascularization by targeting HUWE1 through NF-κb signaling pathway.
Ou K, Li Y, Wang Y, Liu J, Luo Y, Jiang J, Dan J, Tang D, Chen Z, Wu J
International journal of biological macromolecules 2024 Feb;257(Pt 1):128620
International journal of biological macromolecules 2024 Feb;257(Pt 1):128620
Sodium-glucose co-transporter 2 inhibitor canagliflozin modulates myocardial metabolism and inflammation in a swine model for chronic myocardial ischemia.
Harris DD, Sabe SA, Xu CM, Sabra M, Broadwin M, Malhotra A, Li JW, Abid MR, Sellke FW
Surgery 2024 Feb;175(2):265-270
Surgery 2024 Feb;175(2):265-270
Resatorvid (TAK-242) Ameliorates Ulcerative Colitis by Modulating Macrophage Polarization and T Helper Cell Balance via TLR4/JAK2/STAT3 Signaling Pathway.
Huang X, Lin R, Liu H, Dai M, Guo J, Hui W, Liu W, Haerken M, Zheng R, Yushanjiang T, Gao F
Inflammation 2024 Dec;47(6):2108-2128
Inflammation 2024 Dec;47(6):2108-2128
CASIN exerts anti-aging effects through RPL4 on the skin of naturally aging mice.
Zhang Y, Wang X, Huang J, Zhang X, Bu L, Zhang Y, Liang F, Wu S, Zhang M, Zhang L, Zhang L
Aging cell 2024 Dec;23(12):e14333
Aging cell 2024 Dec;23(12):e14333
STAT6 blockade ameliorates thyroid function in Graves' disease via downregulation of the sodium/iodide symporter.
Yang Q, Zhang Q, Pan F, Zha B
Endocrine connections 2024 Dec 1;13(12)
Endocrine connections 2024 Dec 1;13(12)
Alleviation of allergic asthma by rosmarinic acid via gut-lung axis.
Guo HH, Han YX, Rong XJ, Shen Z, Shen HR, Kong LF, Guo YD, Li JZ, Xu B, Gao TL, Wang LL, Tie C, Jiang JD
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155470
Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization.
Zhang R, Jiang Q, Gao S, Zhang H, Xia Q, Liu B, Zhu J, Jiang H, Zhao R, Dong H, Li X, Zhang Y, Yang C, Gu X, Sun L, Zhou H
International immunopharmacology 2024 Apr 20;131:111774
International immunopharmacology 2024 Apr 20;131:111774
A Series of 35 Cutaneous Infections Caused by Mycobacterium marinum in Han Chinese Population.
Chen W, Bao F, Pan Q, Liu T, Xue X, Liu H, Zhang F
Journal of tropical medicine 2023;2023:5514275
Journal of tropical medicine 2023;2023:5514275
Dupilumab improve acquired reactive perforating collagenosis characterized by type 2 inflammation.
Liu B, Wu Y, Wu X, Zhong X, Xue R, Zhang Z
Frontiers in immunology 2023;14:1240262
Frontiers in immunology 2023;14:1240262
Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model mice.
Li X, Ye H, Su T, Hu C, Huang Y, Fu X, Zhong Z, Du X, Zheng Y
Frontiers in immunology 2023;14:1185921
Frontiers in immunology 2023;14:1185921
Antimicrobial peptide-modified AIE visual composite wound dressing for promoting rapid healing of infected wounds.
Chen Y, Qian H, Peng D, Jiang Y, Liu Q, Tan Y, Feng L, Cheng B, Li G
Frontiers in bioengineering and biotechnology 2023;11:1338172
Frontiers in bioengineering and biotechnology 2023;11:1338172
The effect of acupuncture on lateral habenular nucleus and intestinal microflora in depression model rats.
Chen W, Chen Y, Aslam MS, Shen J, Tong T, Yan S, Cheng W, Huang Z, Li J, Liu S, Li J, Zeng J, Li M, You Z, Meng X
Behavioural brain research 2023 Oct 18;455:114627
Behavioural brain research 2023 Oct 18;455:114627
PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.
Yu M, Tang W, Liang W, Xie B, Gao R, Ding P, Gu X, Wang M, Wen S, Sun P
International immunopharmacology 2023 Nov;124(Pt B):110962
International immunopharmacology 2023 Nov;124(Pt B):110962
Expression pattern analysis of m6A regulators reveals IGF2BP3 as a key modulator in osteoarthritis synovial macrophages.
Lu Y, Zhang H, Pan H, Zhang Z, Zeng H, Xie H, Yin J, Tang W, Lin R, Zeng C, Cai D
Journal of translational medicine 2023 May 22;21(1):339
Journal of translational medicine 2023 May 22;21(1):339
Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies.
Shi W, Wang Y, Zhao Y, Kim JJ, Li H, Meng C, Chen F, Zhang J, Mak DH, Van V, Leo J, St Croix B, Aparicio A, Zhao D
Science translational medicine 2023 May 10;15(695):eadf6724
Science translational medicine 2023 May 10;15(695):eadf6724
Investigation of macrophage polarization in herniated nucleus pulposus of patients with lumbar intervertebral disc herniation.
Li XC, Luo SJ, Wu F, Mu QC, Yang JH, Jiang C, Wang W, Zhou TL, Qin TD, Tan RX, Jian-Li, Huang CM, Wang MS, Bai XC
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Jun;41(6):1335-1347
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2023 Jun;41(6):1335-1347
Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.
Sun W, Wang Q, Zhang R, Zhang N
Food & function 2023 Jul 31;14(15):7247-7269
Food & function 2023 Jul 31;14(15):7247-7269
Induced Overexpression of B Cell-Activating Factor by Triiodothyronine Results in Abnormal B Cell Differentiation in Mice.
Liu S, Li GQ, Gu QW, Wang J, Sun Q, Gu WS, Mao XM
Cell transplantation 2023 Jan-Dec;32:9636897231204075
Cell transplantation 2023 Jan-Dec;32:9636897231204075
Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia.
Liu H, Yu L, Ding Y, Peng M, Deng Y
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Cell transplantation 2023 Jan-Dec;32:9636897221145682
Intrahepatic eosinophilic proliferative phlebitis in Japanese black cattle indicate allergies involving mast cell tryptase-dependent activation.
Konnai M, Takahashi K, Machida Y, Michishita M, Ohkusu-Tsukada K
Frontiers in veterinary science 2022;9:972180
Frontiers in veterinary science 2022;9:972180
Neuroprotection of cannabidiol in epileptic rats: Gut microbiome and metabolome sequencing.
Gong X, Liu L, Li X, Xiong J, Xu J, Mao D, Liu L
Frontiers in nutrition 2022;9:1028459
Frontiers in nutrition 2022;9:1028459
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.
Fan R, Dai F, Zhang C, Zhou L, Qiu X, Li Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2112359
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2112359
IL-4 and CCR7 play an important role in the development of keloids in patients with a family history.
Shan M, Liu H, Hao Y, Meng T, Feng C, Song K, Wang Y
American journal of translational research 2022;14(5):3381-3394
American journal of translational research 2022;14(5):3381-3394
Intravenous AAV9 administration results in safe and widespread distribution of transgene in the brain of mini-pig.
Lin Y, Li C, Wang W, Li J, Huang C, Zheng X, Liu Z, Song X, Chen Y, Gao J, Wu J, Wu J, Tu Z, Lai L, Li XJ, Li S, Yan S
Frontiers in cell and developmental biology 2022;10:1115348
Frontiers in cell and developmental biology 2022;10:1115348
Mesoporous silica nanoparticle-modified electrode arrays of cochlear implants for delivery of siRNA-TGFβ1 into the inner ear.
Chen A, Chen Y, Liu S, Ma D, Tang J, Zhang H
Colloids and surfaces. B, Biointerfaces 2022 Oct;218:112753
Colloids and surfaces. B, Biointerfaces 2022 Oct;218:112753
Schisandra chinensis Lignans Exert Antidepressant Effects by Promoting BV2 Microglia Polarization toward the M2 Phenotype through the Activation of the Cannabinoid Receptor Type-2-Signal Transducer and Activator of Transcription 6 Pathway.
Wang J, Zhang G, Yang Y, Zhang X, Shi K, Zhang X, Yan T, Jia Y
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
Journal of agricultural and food chemistry 2022 Nov 9;70(44):14157-14169
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Fan TW, Daneshmandi S, Cassel TA, Uddin MB, Sledziona J, Thompson PT, Lin P, Higashi RM, Lane AN
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Journal of immunology (Baltimore, Md. : 1950) 2022 Nov 1;209(9):1674-1690
Quercetin Alleviates Demyelination Through Regulating Microglial Phenotype Transformation to Mitigate Neuropsychiatric Symptoms in Mice with Vascular Dementia.
Tan Z, Yang G, Qiu J, Yan W, Liu Y, Ma Z, Li J, Liu J, Shan N
Molecular neurobiology 2022 May;59(5):3140-3158
Molecular neurobiology 2022 May;59(5):3140-3158
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Han Y, Yao R, Yang Z, Li S, Meng W, Zhang Y, Zhang Y, Luo H
Experimental cell research 2022 Mar 1;412(1):113002
Experimental cell research 2022 Mar 1;412(1):113002
Chitooligosaccharides alleviate hepatic fibrosis by regulating the polarization of M1 and M2 macrophages.
Liu P, Li H, Gong J, Geng Y, Jiang M, Xu H, Xu Z, Shi J
Food & function 2022 Jan 24;13(2):753-768
Food & function 2022 Jan 24;13(2):753-768
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease.
Hai YP, Saeed MEM, Ponto KA, Elflein HM, Lee ACH, Fang S, Zhou H, Frommer L, Längericht J, Efferth T, Kahaly GJ
Thyroid : official journal of the American Thyroid Association 2022 Dec;32(12):1547-1558
Thyroid : official journal of the American Thyroid Association 2022 Dec;32(12):1547-1558
Circular RNA circWWC3 augments breast cancer progression through promoting M2 macrophage polarization and tumor immune escape via regulating the expression and secretion of IL-4.
Zheng Y, Ren S, Zhang Y, Liu S, Meng L, Liu F, Gu L, Ai N, Sang M
Cancer cell international 2022 Aug 22;22(1):264
Cancer cell international 2022 Aug 22;22(1):264
Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization.
Cui X, Qin T, Zhao Z, Yang G, Sanches JGP, Zhang Q, Fan S, Cao L, Hu X
Journal of Cancer 2021;12(15):4686-4697
Journal of Cancer 2021;12(15):4686-4697
Nuclear factor erythroid 2-related factor 2 potentiates the generation of inflammatory cytokines by intestinal epithelial cells during hyperoxia by inducing the expression of interleukin 17D.
Liu X, Li T, Liu Y, Sun S, Liu D
Toxicology 2021 Jun 15;457:152820
Toxicology 2021 Jun 15;457:152820
STAT6 up-regulation amplifies M2 macrophage anti-inflammatory capacity through mesenchymal stem cells.
Li Y, Sheng Q, Zhang C, Han C, Bai H, Lai P, Fan Y, Ding Y, Dou X
International immunopharmacology 2021 Feb;91:107266
International immunopharmacology 2021 Feb;91:107266
Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis.
Han Z, Wang H, Guo D, Zhang J
Aging 2021 Feb 1;13(4):5087-5103
Aging 2021 Feb 1;13(4):5087-5103
DJ-1 Regulates Microglial Polarization Through P62-Mediated TRAF6/IRF5 Signaling in Cerebral Ischemia-Reperfusion.
Wang T, Zhao N, Peng L, Li Y, Huang X, Zhu J, Chen Y, Yu S, Zhao Y
Frontiers in cell and developmental biology 2020;8:593890
Frontiers in cell and developmental biology 2020;8:593890
Interleukin-4 Restores Insulin Sensitivity in Insulin-Resistant Osteoblasts by Increasing the Expression of Insulin Receptor Substrate 1.
Chao R, Li D, Yue Z, Huang C, Kou Y, Zhou Q, Gao Y, Hasegawa T, Guo J, Li M
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343
Biochemistry. Biokhimiia 2020 Mar;85(3):334-343
Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats.
Zhou S, Chen S, Xie W, Guo X, Zhao J
Neuropeptides 2020 Jun;81:102006
Neuropeptides 2020 Jun;81:102006
Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity.
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, Tucker L, Zhao N, Brann DW, Yan X, Hu S, Zhang Q
Translational stroke research 2020 Jun;11(3):450-467
Translational stroke research 2020 Jun;11(3):450-467
Neural stem cells induce M2 polarization of macrophages through the upregulation of interleukin-4.
Ji Z, Jiang X, Li Y, Song J, Chai C, Lu X
Experimental and therapeutic medicine 2020 Dec;20(6):148
Experimental and therapeutic medicine 2020 Dec;20(6):148
Comparative Immunopathology of Cetacean morbillivirus Infection in Free-Ranging Dolphins From Western Mediterranean, Northeast-Central, and Southwestern Atlantic.
Díaz-Delgado J, Groch KR, Ressio R, Riskallah IPJ, Sierra E, Sacchini S, Quesada-Canales Ó, Arbelo M, Fernández A, Santos-Neto E, Ikeda J, de Carvalho RR, Azevedo AF, Lailson-Brito J Jr, Flach L, Kanamura CT, Fernandes NCCA, Cogliati B, Centelleghe C, Mazzariol S, Di Renzo L, Di Francesco G, Di Guardo G, Catão-Dias JL
Frontiers in immunology 2019;10:485
Frontiers in immunology 2019;10:485
Macrophage polarization in human gingival tissue in response to periodontal disease.
Zhou LN, Bi CS, Gao LN, An Y, Chen F, Chen FM
Oral diseases 2019 Jan;25(1):265-273
Oral diseases 2019 Jan;25(1):265-273
Juxtaposition of IL-1β and IFN-γ expression and apoptosis of keratinocytes in adult-onset Still's disease.
Rao S, Li Q, Wu H, Zhao M, Wang A, Zhang G, Li J, Lu L, Shi W, Lu Q
Expert review of clinical immunology 2019 Dec;15(12):1341-1350
Expert review of clinical immunology 2019 Dec;15(12):1341-1350
Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells.
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, Zhang J, Liu TC, Zhang Q
Experimental neurology 2018 Jan;299(Pt A):86-96
Experimental neurology 2018 Jan;299(Pt A):86-96
Pre-transplant infusion of donor-derived dendritic cells maintained at the immature stage by sinomenine increases splenic Foxp3(+) Tregs in recipient rats after renal allotransplantation.
Li L, Luo Z, Song Z, Zheng L, Chen T
Transplant immunology 2017 Dec;45:22-28
Transplant immunology 2017 Dec;45:22-28
Upregulated Expression of microRNA-16 Correlates with Th17/Treg Cell Imbalance in Patients with Rheumatoid Arthritis.
Wu YH, Liu W, Xue B, Zhang L, Liu XY, Liu B, Wang Y, Cai Y, Duan R
DNA and cell biology 2016 Dec;35(12):853-860
DNA and cell biology 2016 Dec;35(12):853-860
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Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The IL-4 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human IL-4. This antibody recognizes human antigen. The IL-4 antibody has been validated for the following applications: ELISA, WB analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 66142-1-Ig( IL4 Antibody) at dilution of 1:1000
- Sample type
- cell line