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- Antibody Data
- Antigen structure
- References [23]
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- Validations
- Western blot [1]
- Immunoprecipitation [2]
- Immunohistochemistry [2]
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- Product number
- 13930-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13930-1-AP, RRID:AB_2132063
- Product name
- KIF3A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated KIF3A antibody (Cat. #13930-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Enhanced release of ciliary extracellular vesicles suppresses cell migration and promotes cell aggregation.
A type of pancreatic cancer cells form cell clusters from a solitary condition in a primary ciliogenesis-dependent manner.
EMT-ciliary signaling in quasi-mesenchymal-stem-like cells drives therapeutic resistance and is a druggable vulnerability in triple-negative breast cancer.
Prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2.
A primary cilia-autophagy axis in hippocampal neurons is essential to maintain cognitive resilience.
TCTEX1D2 is essential for sperm flagellum formation in mice.
SMOC2 (high) myofibroblastic cancer-associated fibroblast drives primary cilia-associated tumor microenvironment remodeling and poor prognosis in gastric cancer.
Lipid droplets sequester palmitic acid to disrupt endothelial ciliation and exacerbate atherosclerosis in male mice.
Inhibition of primary cilia-hedgehog signaling axis triggers autophagic cell death and suppresses malignant progression of VHL wild-type ccRCC.
Primary cilium participates in radiation-induced bystander effects through TGF-β1 signaling.
Phosphorylation of MIF by PIP4K2a is necessary for cilia biogenesis.
A stress-induced cilium-to-PML-NB route drives senescence initiation.
An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis.
DAB2IP modulates primary cilia formation associated with renal tumorigenesis.
NEK7 promotes gastric cancer progression as a cell proliferation regulator.
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium.
Requirement of NPHP5 in the hierarchical assembly of basal feet associated with basal bodies of primary cilia.
Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development.
Type I collagen-induced YAP nuclear expression promotes primary cilia growth and contributes to cell migration in confluent mouse embryo fibroblast 3T3-L1 cells.
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling.
Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase.
Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
Hara T, Nakazato R, Shirakawa K, Ijaz F, Uemura K, Takahashi S, Ikegami K
Cell structure and function 2026 Feb 20;51(1):67-79
Cell structure and function 2026 Feb 20;51(1):67-79
A type of pancreatic cancer cells form cell clusters from a solitary condition in a primary ciliogenesis-dependent manner.
Shirakawa K, Nakazato R, Hara T, Uemura K, Ijaz F, Takahashi S, Ikegami K
Medical molecular morphology 2025 Sep;58(3):213-226
Medical molecular morphology 2025 Sep;58(3):213-226
EMT-ciliary signaling in quasi-mesenchymal-stem-like cells drives therapeutic resistance and is a druggable vulnerability in triple-negative breast cancer.
Tessier CE, Derrien J, Dupuy AMM, Pelé T, Moquet M, Roul J, Douillard E, El Harrif C, Pinson X, Le Gallo M, Godey F, Tas P, Viel R, Grasset E, Prigent C, Letouzé É, Suzanne P, Dallemagne P, Campone M, Weinberg RA, Lees JA, Juin PP, Guen VJ
EMBO molecular medicine 2025 Oct;17(10):2536-2561
EMBO molecular medicine 2025 Oct;17(10):2536-2561
Prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2.
Lee MD, Hilgendorf KI
Journal of cell science 2025 Oct 15;138(20)
Journal of cell science 2025 Oct 15;138(20)
A primary cilia-autophagy axis in hippocampal neurons is essential to maintain cognitive resilience.
Rivagorda M, Romeo-Guitart D, Blanchet V, Mailliet F, Boitez V, Barry N, Milunov D, Siopi E, Goudin N, Moriceau S, Guerrera C, Leibovici M, Saha S, Codogno P, Morselli E, Morel E, Armand AS, Oury F
Nature aging 2025 Mar;5(3):450-467
Nature aging 2025 Mar;5(3):450-467
TCTEX1D2 is essential for sperm flagellum formation in mice.
Harima R, Hara K, Tanemura K
Scientific reports 2025 Jan 18;15(1):2413
Scientific reports 2025 Jan 18;15(1):2413
SMOC2 (high) myofibroblastic cancer-associated fibroblast drives primary cilia-associated tumor microenvironment remodeling and poor prognosis in gastric cancer.
Xu Q, Yang C, Ning J, Niu Y, Zhao X, Zhao L, Wang C, Wang S, Ye Y, Shen Z
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2025 Aug 30;37(4):603-623
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu 2025 Aug 30;37(4):603-623
Lipid droplets sequester palmitic acid to disrupt endothelial ciliation and exacerbate atherosclerosis in male mice.
Tan Y, Huang Z, Jin Y, Wang J, Fan H, Liu Y, Zhang L, Wu Y, Liu P, Li T, Ran J, Tian H, Lam SM, Liu M, Zhou J, Yang Y
Nature communications 2024 Sep 27;15(1):8273
Nature communications 2024 Sep 27;15(1):8273
Inhibition of primary cilia-hedgehog signaling axis triggers autophagic cell death and suppresses malignant progression of VHL wild-type ccRCC.
Tian S, Du S, Wang C, Zhang Y, Wang H, Fan Y, Gao Y, Gu L, Huang Q, Wang B, Ma X, Zhang X, Huang Y
Cell death & disease 2024 Oct 10;15(10):739
Cell death & disease 2024 Oct 10;15(10):739
Primary cilium participates in radiation-induced bystander effects through TGF-β1 signaling.
Qu P, Shao Z, Zhang Y, He J, Lu D, Wei W, Hua J, Wang W, Wang J, Ding N
Journal of cellular physiology 2024 Feb;239(2):e31163
Journal of cellular physiology 2024 Feb;239(2):e31163
Phosphorylation of MIF by PIP4K2a is necessary for cilia biogenesis.
Zhang L, Zhang H, Agborbesong E, Zhou JX, Li X
Cell death & disease 2023 Dec 5;14(12):795
Cell death & disease 2023 Dec 5;14(12):795
A stress-induced cilium-to-PML-NB route drives senescence initiation.
Ma X, Zhang Y, Zhang Y, Zhang X, Huang Y, He K, Chen C, Hao J, Zhao D, LeBrasseur NK, Kirkland JL, Chini EN, Wei Q, Ling K, Hu J
Nature communications 2023 Apr 3;14(1):1840
Nature communications 2023 Apr 3;14(1):1840
An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis.
Wilson MM, Callens C, Le Gallo M, Mironov S, Ding Q, Salamagnon A, Chavarria TE, Viel R, Peasah AD, Bhutkar A, Martin S, Godey F, Tas P, Kang HS, Juin PP, Jetten AM, Visvader JE, Weinberg RA, Attanasio M, Prigent C, Lees JA, Guen VJ
Science advances 2021 Oct 29;7(44):eabf6063
Science advances 2021 Oct 29;7(44):eabf6063
DAB2IP modulates primary cilia formation associated with renal tumorigenesis.
Lin CJ, Dang A, Hernandez E, Hsieh JT
Neoplasia (New York, N.Y.) 2021 Jan;23(1):169-180
Neoplasia (New York, N.Y.) 2021 Jan;23(1):169-180
NEK7 promotes gastric cancer progression as a cell proliferation regulator.
Li YK, Zhu XR, Zhan Y, Yuan WZ, Jin WL
Cancer cell international 2021 Aug 21;21(1):438
Cancer cell international 2021 Aug 21;21(1):438
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium.
Boukhalfa A, Roccio F, Dupont N, Codogno P, Morel E
Cell reports 2021 Apr 27;35(4):109045
Cell reports 2021 Apr 27;35(4):109045
Requirement of NPHP5 in the hierarchical assembly of basal feet associated with basal bodies of primary cilia.
Hossain D, Barbelanne M, Tsang WY
Cellular and molecular life sciences : CMLS 2020 Jan;77(1):195-212
Cellular and molecular life sciences : CMLS 2020 Jan;77(1):195-212
Roles for IFT172 and Primary Cilia in Cell Migration, Cell Division, and Neocortex Development.
Pruski M, Hu L, Yang C, Wang Y, Zhang JB, Zhang L, Huang Y, Rajnicek AM, St Clair D, McCaig CD, Lang B, Ding YQ
Frontiers in cell and developmental biology 2019;7:287
Frontiers in cell and developmental biology 2019;7:287
Type I collagen-induced YAP nuclear expression promotes primary cilia growth and contributes to cell migration in confluent mouse embryo fibroblast 3T3-L1 cells.
Xu Q, Liu X, Liu W, Hayashi T, Yamato M, Fujisaki H, Hattori S, Tashiro SI, Onodera S, Ikejima T
Molecular and cellular biochemistry 2019 Jan;450(1-2):87-96
Molecular and cellular biochemistry 2019 Jan;450(1-2):87-96
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY
Nature communications 2018 Dec 11;9(1):5277
Nature communications 2018 Dec 11;9(1):5277
EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling.
Guen VJ, Chavarria TE, Kröger C, Ye X, Weinberg RA, Lees JA
Proceedings of the National Academy of Sciences of the United States of America 2017 Dec 5;114(49):E10532-E10539
Proceedings of the National Academy of Sciences of the United States of America 2017 Dec 5;114(49):E10532-E10539
Arborization of dendrites by developing neocortical neurons is dependent on primary cilia and type 3 adenylyl cyclase.
Guadiana SM, Semple-Rowland S, Daroszewski D, Madorsky I, Breunig JJ, Mykytyn K, Sarkisian MR
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Feb 6;33(6):2626-38
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Feb 6;33(6):2626-38
Kif3a interacts with Dynactin subunit p150 Glued to organize centriole subdistal appendages.
Kodani A, Salomé Sirerol-Piquer M, Seol A, Garcia-Verdugo JM, Reiter JF
The EMBO journal 2013 Feb 20;32(4):597-607
The EMBO journal 2013 Feb 20;32(4):597-607
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human cerebellum tissue were subjected to SDS PAGE followed by western blot with 13930-1-AP(KIF3A antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- WB and IP result of the antibdoy anti-KIF3A (13930-1-AP) in mouse cell from Corbit, Kevin.
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-KIF3A (IP:13930-1-AP, 4ug; Detection:13930-1-AP 1:500) with mouse brain tissue lysate 8000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 13930-1-AP(KIF3A antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KIF3A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human KIF3A. This antibody recognizes human, mouse antigen. The KIF3A antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
