BS8077

antibody from Bioworld Technology, Inc
Targeting: ILF2 NF45
Provider product page for BS8077
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8077 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ILF2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human ILF2.
Description
NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ILF2 protein structure - BS8077 shown in red.