Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 17361-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- LY6D antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LY6D antibody (Cat. #17361-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells.
FOSL2 deficiency delays nonalcoholic steatohepatitis progression by regulating LY6D-mediated NLRP3 activation.
LY6D marks pre-existing resistant basosquamous tumor subpopulations.
Construction of ceRNA network to identify the lncRNA and mRNA related to non-small cell lung cancer.
c-FOS drives reversible basal to squamous cell carcinoma transition.
Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis.
AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma.
RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development.
Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d.
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ERα/HGF/Met Pathway.
Steiner I, Flores-Tellez TDNJ, Mevel R, Ali A, Wang P, Schofield P, Behan C, Forsythe N, Ashton G, Taylor C, Mills IG, Oliveira P, McDade SS, Zaiss DM, Choudhury A, Lacaud G, Baena E
Cell reports 2023 Apr 25;42(4):112377
Cell reports 2023 Apr 25;42(4):112377
FOSL2 deficiency delays nonalcoholic steatohepatitis progression by regulating LY6D-mediated NLRP3 activation.
Hu PX, Sheng MY, Liu YP, Zhang CQ
Human cell 2022 Nov;35(6):1752-1765
Human cell 2022 Nov;35(6):1752-1765
LY6D marks pre-existing resistant basosquamous tumor subpopulations.
Haensel D, Gaddam S, Li NY, Gonzalez F, Patel T, Cloutier JM, Sarin KY, Tang JY, Rieger KE, Aasi SZ, Oro AE
Nature communications 2022 Dec 6;13(1):7520
Nature communications 2022 Dec 6;13(1):7520
Construction of ceRNA network to identify the lncRNA and mRNA related to non-small cell lung cancer.
Xiao K, Wang Y, Zhou L, Wang J, Wang Y, Tong D, Zhu Z, Jiang J
PloS one 2021;16(10):e0259091
PloS one 2021;16(10):e0259091
c-FOS drives reversible basal to squamous cell carcinoma transition.
Kuonen F, Li NY, Haensel D, Patel T, Gaddam S, Yerly L, Rieger K, Aasi S, Oro AE
Cell reports 2021 Oct 5;37(1):109774
Cell reports 2021 Oct 5;37(1):109774
Investigation of Candidate Genes and Pathways in Basal/TNBC Patients by Integrated Analysis.
Liu Q, Song X, Liu Z, Yu Z
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211019506
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211019506
AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma.
Yao CD, Haensel D, Gaddam S, Patel T, Atwood SX, Sarin KY, Whitson RJ, McKellar S, Shankar G, Aasi S, Rieger K, Oro AE
Nature communications 2020 Oct 8;11(1):5079
Nature communications 2020 Oct 8;11(1):5079
RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development.
Mevel R, Steiner I, Mason S, Galbraith LC, Patel R, Fadlullah MZ, Ahmad I, Leung HY, Oliveira P, Blyth K, Baena E, Lacaud G
eLife 2020 Oct 7;9
eLife 2020 Oct 7;9
Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d.
Semba T, Sato R, Kasuga A, Suina K, Shibata T, Kohno T, Suzuki M, Saya H, Arima Y
Cancers 2020 Dec 17;12(12)
Cancers 2020 Dec 17;12(12)
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration.
Pepe-Mooney BJ, Dill MT, Alemany A, Ordovas-Montanes J, Matsushita Y, Rao A, Sen A, Miyazaki M, Anakk S, Dawson PA, Ono N, Shalek AK, van Oudenaarden A, Camargo FD
Cell stem cell 2019 Jul 3;25(1):23-38.e8
Cell stem cell 2019 Jul 3;25(1):23-38.e8
Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ERα/HGF/Met Pathway.
Zhang YY, Li C, Yao GF, Du LJ, Liu Y, Zheng XJ, Yan S, Sun JY, Liu Y, Liu MZ, Zhang X, Wei G, Tong W, Chen X, Wu Y, Sun S, Liu S, Ding Q, Yu Y, Yin H, Duan SZ
Diabetes 2017 Jun;66(6):1535-1547
Diabetes 2017 Jun;66(6):1535-1547
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse spleen tissue were subjected to SDS PAGE followed by western blot with 17361-1-AP( LY6D Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LY6D antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human LY6D. This antibody recognizes human, mouse antigen. The LY6D antibody has been validated for the following applications: ELISA, WB, IHC analysis.