Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- HPA049407 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA049407, RRID:AB_2680750
- Product name
- Anti-SEC61B
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SEC61B, Gene description: Sec61 beta subunit, Validated applications: ICC, IHC, Uniprot ID: P60468, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.05 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Nonvesicular lipid transfer drives myelin growth in the central nervous system
Homotypic SCOTIN assemblies form ERāendosome membrane contacts and regulate endosome dynamics
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
Wu J, Kislinger G, Duschek J, Durmaz A, Wefers B, Feng R, Nalbach K, Wurst W, Behrends C, Schifferer M, Simons M
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
Homotypic SCOTIN assemblies form ERāendosome membrane contacts and regulate endosome dynamics
Yun H, Jung M, Lee H, Jung S, Kim T, Kim N, Park S, Kim W, Mun J, Yoo J
EMBO reports 2023;24(8)
EMBO reports 2023;24(8)
SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores
Lee J, Kim N, Jung M, Mun J, Yoo J
Autophagy 2021;18(7):1613-1628
Autophagy 2021;18(7):1613-1628
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
Neggers J, Paolella B, Asfaw A, Rothberg M, Skipper T, Yang A, Kalekar R, Krill-Burger J, Dharia N, Kugener G, Kalfon J, Yuan C, Dumont N, Gonzalez A, Abdusamad M, Li Y, Spurr L, Wu W, Durbin A, Wolpin B, Piccioni F, Root D, Boehm J, Cherniack A, Tsherniak A, Hong A, Hahn W, Stegmaier K, Golub T, Vazquez F, Aguirre A
Cell Reports 2020;33(11):108493
Cell Reports 2020;33(11):108493
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line PC-3 shows localization to endoplasmic reticulum.
- Sample type
- Human