FNab00197

antibody from FineTest Biotech

Targeting: AFF4 AF5Q31, MCEF

Western blot

ELISA

Immunoprecipitation

Antibody data

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Validation data

Product number: FNab00197 - Provider product page
Provider: FineTest Biotech
Product name: AFF4 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AF4/FMR2 family, member 4
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

AFF4 protein structure - FNab00197 shown in red.