22144-1-AP

antibody from Proteintech Group

Targeting: LY6E RIG-E, SCA-2, TSA-1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

22144-1-AP

Provider

Proteintech Group

Product name

LY6E antibody

Antibody type

Polyclonal

Description

KD/KO validated LY6E antibody (Cat. #22144-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, Mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Glycosylphosphatidylinositol biosynthesis functions as a conserved host defense pathway against coronaviruses via regulation of LY6E.

Ma Y, Feng F, Feng H, Ma X, Wang Z, Han Y, Zhu Y, Wang Y, Gao Z, Zhang Y, Ding Q, Zhao J, Zhang R
PLoS pathogens 2025 Sep;21(9):e1013441

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Nuclear PD-L1 drives IFN-γ-promoted lung metastasis of triple-negative breast cancer via POLR2A-mediated transcriptional activation of LY6E.

Wang X, Zhou Q, Wang P, Bao S, Wei X, Zhao X, Hou R, Li S, Guan Z, Ma W, Zheng J, Liu D, Shi M
Breast cancer research : BCR 2025 Dec 12;28(1):14

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Characterization of CCoV-HuPn-2018 spike protein-mediated viral entry.

Liu Y, Chen D, Wang Y, Li X, Qiu Y, Zheng M, Song Y, Li G, Song C, Liu T, Zhang Y, Guo JT, Lin H, Zhao X
Journal of virology 2023 Sep 28;97(9):e0060123

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LY6E protein facilitates adeno-associated virus crossing in a biomimetic chip model of the human blood-brain barrier.

Liu D, Zhu M, Lin Y, Li M, Huang R, Yang L, Song Y, Diao Y, Yang C
Lab on a chip 2022 Oct 25;22(21):4180-4190

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α5-nAChR associated with Ly6E modulates cell migration via TGF-β1/Smad signaling in non-small cell lung cancer.

Zhang Q, Jia Y, Pan P, Zhang X, Jia Y, Zhu P, Chen X, Jiao Y, Kang G, Zhang L, Ma X
Carcinogenesis 2022 May 19;43(4):393-404

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LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2.

Zhao X, Zheng S, Chen D, Zheng M, Li X, Li G, Lin H, Chang J, Zeng H, Guo JT
Journal of virology 2020 Aug 31;94(18)