Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [7]
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Validation data
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- Product number
- HPA021191 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA021191, RRID:AB_1856395
- Product name
- Anti-CROCC
- Antibody type
- Polyclonal
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
VKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAA
LETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSER
TADASNGS- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Submitted references Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia
DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites
Wallmeier J, Al-Mutairi D, Chen C, Loges N, Pennekamp P, Menchen T, Ma L, Shamseldin H, Olbrich H, Dougherty G, Werner C, Alsabah B, Köhler G, Jaspers M, Boon M, Griese M, Schmitt-Grohé S, Zimmermann T, Koerner-Rettberg C, Horak E, Kintner C, Alkuraya F, Omran H
Nature Genetics 2014 April;46(6):646-651
Nature Genetics 2014 April;46(6):646-651
DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites
Löffler H, Fechter A, Liu F, Poppelreuther S, Krämer A
Oncogene 2012 July;32(24):2963-2972
Oncogene 2012 July;32(24):2963-2972
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis in human cell line SCLC-21H.
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, centrosome & actin filaments.
- Sample type
- HUMAN
Enhanced validation
Enhanced validation
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human fallopian tube and liver tissues using Anti-CROCC antibody. Corresponding CROCC RNA-seq data are presented for the same tissues.
- Sample type
- HUMAN
Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Independent antibody validation
- Main image
- Experimental details
- Immunohistochemical staining of human cerebral cortex, fallopian tube, lymph node and testis using Anti-CROCC antibody HPA021191 (A) shows similar protein distribution across tissues to independent antibody HPA021762 (B).
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human fallopian tube shows high expression.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human liver shows low expression as expected.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human lymph node using Anti-CROCC antibody HPA021191.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human cerebral cortex using Anti-CROCC antibody HPA021191.
- Sample type
- HUMAN
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human testis using Anti-CROCC antibody HPA021191.
- Sample type
- HUMAN