Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN2841942 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-LIM Domain Kinase 1 (LIMK1) (AA 1-30), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 1-30, N-Term
- Antibody clone number
- RB3078
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop.
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.
Structural features of LIM kinase that control effects on the actin cytoskeleton.
LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition.
Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, Mizuno K
The Journal of biological chemistry 2000 Feb 4;275(5):3577-82
The Journal of biological chemistry 2000 Feb 4;275(5):3577-82
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase.
Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, Obinata T, Ohashi K, Mizuno K, Narumiya S
Science (New York, N.Y.) 1999 Aug 6;285(5429):895-8
Science (New York, N.Y.) 1999 Aug 6;285(5429):895-8
Structural features of LIM kinase that control effects on the actin cytoskeleton.
Edwards DC, Gill GN
The Journal of biological chemistry 1999 Apr 16;274(16):11352-61
The Journal of biological chemistry 1999 Apr 16;274(16):11352-61
LIM-kinase1 hemizygosity implicated in impaired visuospatial constructive cognition.
Frangiskakis JM, Ewart AK, Morris CA, Mervis CB, Bertrand J, Robinson BF, Klein BP, Ensing GJ, Everett LA, Green ED, Pröschel C, Gutowski NJ, Noble M, Atkinson DL, Odelberg SJ, Keating MT
Cell 1996 Jul 12;86(1):59-69
Cell 1996 Jul 12;86(1):59-69
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC