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- Product number
- 10051-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10051-1-AP, RRID:AB_2220309
- Product name
- BCRP/ABCG2 antibody
- Antibody type
- Polyclonal
- Description
- BCRP/ABCG2 antibody (Cat. #10051-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references p38 inhibition restores chemosensitivity of tumor cells by disrupting oligomerized breast cancer resistance protein membrane trafficking.
Synergistic mechanisms of Banxia Xiexin decoction in overcoming chemoresistance and enhancing chemosensitivity in colorectal cancer.
Gut-kidney axis modulation by viable and inactivated Akkermansia muciniphila mitigates avian hyperuricemia through microbial-metabolic crosstalk.
The impact of chrysanthemi indici flos-enriched flavonoid part on the model of hyperuricemia based on inhibiting synthesis and promoting excretion of uric acid.
The Anthraquinone Derivative C2 Enhances Oxaliplatin-Induced Cell Death and Triggers Autophagy via the PI3K/AKT/mTOR Pathway.
Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.
Effects of Smilax China L. extracts on Hyperuricemia chicken model via inhibiting xanthine oxidase activity.
Multi-time point metabolomics reveals key metabolic features from the ultra-early stage of intracerebral hemorrhage in mice.
Interaction between CD9 and PI3K‑p85 activates the PI3K/AKT signaling pathway in B‑lineage acute lymphoblastic leukemia.
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Interferon regulatory factor-1 reverses chemoresistance by downregulating the expression of P-glycoprotein in gastric cancer.
MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer.
Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor.
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin.
Enhanced Sensitivity of Cancer Stem Cells to Chemotherapy Using Functionalized Mesoporous Silica Nanoparticles.
PET study on mice bearing human colon adenocarcinoma cells using [11C]GF120918, a dual radioligand for P-glycoprotein and breast cancer resistance protein.
Membrane topology of the human breast cancer resistance protein (BCRP/ABCG2) determined by epitope insertion and immunofluorescence.
Pan Y, Zhu Z, Zhu Y, Hu T, Zhang Z, Fan H, Yu S, Wei Z, Wang A, Lu Y, Chen W
iScience 2026 Jan 16;29(1):114359
iScience 2026 Jan 16;29(1):114359
Synergistic mechanisms of Banxia Xiexin decoction in overcoming chemoresistance and enhancing chemosensitivity in colorectal cancer.
Yue Y, Chen M, Qin Y, Qian Y, Cui T, Liu T, Su L, Li Z, Yan S
Fitoterapia 2025 Sep;185:106711
Fitoterapia 2025 Sep;185:106711
Gut-kidney axis modulation by viable and inactivated Akkermansia muciniphila mitigates avian hyperuricemia through microbial-metabolic crosstalk.
Fu Y, Chen J, Cao Q, Zhu S, Chen W, Luo H, Zhao Y, Bernard LA, Wang X, Tu Q, Zhang Y, Jiang X, Yang L, Wang W
mSystems 2025 Sep 23;10(9):e0077325
mSystems 2025 Sep 23;10(9):e0077325
The impact of chrysanthemi indici flos-enriched flavonoid part on the model of hyperuricemia based on inhibiting synthesis and promoting excretion of uric acid.
Jiao L, Wang R, Dong Y, Su J, Yu J, Yan M, Chen S, Lv G
Journal of ethnopharmacology 2024 Oct 28;333:118488
Journal of ethnopharmacology 2024 Oct 28;333:118488
The Anthraquinone Derivative C2 Enhances Oxaliplatin-Induced Cell Death and Triggers Autophagy via the PI3K/AKT/mTOR Pathway.
Li Y, Yan W, Qin Y, Zhang L, Xiao S
International journal of molecular sciences 2024 Jun 12;25(12)
International journal of molecular sciences 2024 Jun 12;25(12)
Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.
Du J, Wang N, Yu D, He P, Gao Y, Tu Y, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155305
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155305
Effects of Smilax China L. extracts on Hyperuricemia chicken model via inhibiting xanthine oxidase activity.
Yan M, Zheng X, Lin Y, Zheng X, Xi K, Gao Y, Wang H, Li Y, Liu C
Poultry science 2024 Aug;103(8):103887
Poultry science 2024 Aug;103(8):103887
Multi-time point metabolomics reveals key metabolic features from the ultra-early stage of intracerebral hemorrhage in mice.
Xiao Z, Li P, Shen Y, Manaenko A, Yang W, Wang P, Li X, Liu F, Xie P, Li Q
Experimental neurology 2023 Oct;368:114507
Experimental neurology 2023 Oct;368:114507
Interaction between CD9 and PI3K‑p85 activates the PI3K/AKT signaling pathway in B‑lineage acute lymphoblastic leukemia.
Shi YF, Huang ZY, Huang YS, Dong RJ, Xing CY, Yu K, Leung KT, Feng JH
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.
Yadav VK, Huang YJ, George TA, Wei PL, Sumitra MR, Ho CL, Chang TH, Wu ATH, Huang HS
Cancers 2020 Jun 16;12(6)
Cancers 2020 Jun 16;12(6)
Interferon regulatory factor-1 reverses chemoresistance by downregulating the expression of P-glycoprotein in gastric cancer.
Yuan J, Yin Z, Tan L, Zhu W, Tao K, Wang G, Shi W, Gao J
Cancer letters 2019 Aug 10;457:28-39
Cancer letters 2019 Aug 10;457:28-39
MicroRNA-132 and microRNA-212 mediate doxorubicin resistance by down-regulating the PTEN-AKT/NF-κB signaling pathway in breast cancer.
Xie M, Fu Z, Cao J, Liu Y, Wu J, Li Q, Chen Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:286-294
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:286-294
Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor.
Zhu WJ, Yang SD, Qu CX, Zhu QL, Chen WL, Li F, Yuan ZQ, Liu Y, You BG, Zhang XN
International journal of nanomedicine 2017;12:3375-3393
International journal of nanomedicine 2017;12:3375-3393
Knockdown of SALL4 expression using RNA interference induces cell cycle arrest, enhances early apoptosis, inhibits invasion and increases chemosensitivity to temozolomide in U251 glioma cells.
Zhang L, Yan Y, Jiang Y, Qian J, Jiang L, Hu G, Lu Y, Luo C
Oncology letters 2017 Oct;14(4):4263-4269
Oncology letters 2017 Oct;14(4):4263-4269
Promoting tumorigenesis in nasopharyngeal carcinoma, NEDD8 serves as a potential theranostic target.
Xie P, Yang JP, Cao Y, Peng LX, Zheng LS, Sun R, Meng DF, Wang MY, Mei Y, Qiang YY, Cao L, Xiang YQ, Luo DH, Yun JP, Huang BJ, Jia LJ, Qian CN
Cell death & disease 2017 Jun 1;8(6):e2834
Cell death & disease 2017 Jun 1;8(6):e2834
Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin.
He L, Guo Y, Deng Y, Li C, Zuo C, Peng W
Xenobiotica; the fate of foreign compounds in biological systems 2017 Feb;47(2):154-163
Xenobiotica; the fate of foreign compounds in biological systems 2017 Feb;47(2):154-163
Enhanced Sensitivity of Cancer Stem Cells to Chemotherapy Using Functionalized Mesoporous Silica Nanoparticles.
Chen Z, Zhu P, Zhang Y, Liu Y, He Y, Zhang L, Gao Y
Molecular pharmaceutics 2016 Aug 1;13(8):2749-59
Molecular pharmaceutics 2016 Aug 1;13(8):2749-59
PET study on mice bearing human colon adenocarcinoma cells using [11C]GF120918, a dual radioligand for P-glycoprotein and breast cancer resistance protein.
Yamasaki T, Kawamura K, Hatori A, Yui J, Yanamoto K, Yoshida Y, Ogawa M, Nengaki N, Wakisaka H, Fukumura T, Zhang MR
Nuclear medicine communications 2010 Nov;31(11):985-93
Nuclear medicine communications 2010 Nov;31(11):985-93
Membrane topology of the human breast cancer resistance protein (BCRP/ABCG2) determined by epitope insertion and immunofluorescence.
Wang H, Lee EW, Cai X, Ni Z, Zhou L, Mao Q
Biochemistry 2008 Dec 30;47(52):13778-87
Biochemistry 2008 Dec 30;47(52):13778-87
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BCRP/ABCG2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BCRP/ABCG2. This antibody recognizes human, mouse antigen. The BCRP/ABCG2 antibody has been validated for the following applications: ELISA, WB analysis.
