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- References [2]
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- Western blot [1]
- Flow cytometry [1]
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- Product number
- PAB3158 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3158, RRID:AB_1570824
- Product name
- ABCG2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human ABCG2.
- Reactivity
- Human
- Host
- Rabbit
- Vial size
- 400 µl
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The 44-kDa Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells.
In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs.
Xie Y, Xu K, Linn DE, Yang X, Guo Z, Shimelis H, Nakanishi T, Ross DD, Chen H, Fazli L, Gleave ME, Qiu Y
The Journal of biological chemistry 2008 Feb 8;283(6):3349-56
The Journal of biological chemistry 2008 Feb 8;283(6):3349-56
In vitro evaluation of photosensitivity risk related to genetic polymorphisms of human ABC transporter ABCG2 and inhibition by drugs.
Tamura A, Onishi Y, An R, Koshiba S, Wakabayashi K, Hoshijima K, Priebe W, Yoshida T, Kometani S, Matsubara T, Mikuriya K, Ishikawa T
Drug metabolism and pharmacokinetics 2007 Dec;22(6):428-40
Drug metabolism and pharmacokinetics 2007 Dec;22(6):428-40
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of ABCG2 polyclonal antibody (Cat # PAB3158) in HepG2 cell line lysates (35 ug/lane). ABCG2 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Validation comment
- Western Blot (Cell lysate)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of HepG2 cells using ABCG2 polyclonal antibody (Cat # PAB3158)(bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry
