Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx015756 - Provider product page
- Provider
- Abbexa
- Product name
- Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) Antibody
- Antibody type
- Monoclonal
- Description
- The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance.It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure.Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta.Low expression in small intestine, liver and colon.
- Reactivity
- Human, Mouse, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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