abx015756

antibody from Abbexa

Targeting: ABCG2 ABCP, BCRP, CD338, EST157481, MXR

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

abx015756

Provider

Abbexa

Product name

Broad Substrate Specificity ATP-Binding Cassette Transporter ABCG2 (ABCG2) Antibody

Antibody type

Monoclonal

Description

The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance.It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure.Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta.Low expression in small intestine, liver and colon.

Reactivity

Human, Mouse, Simian

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.