332018

ABCG2 antibody from BioLegend
ABCP, BCRP, CD338, EST157481, MXR

Antibody data

Product number
332018
Provider
BioLegend
Proper citation
BioLegend Cat#332018, RRID:AB_1186121
Product name
PerCP/Cy5.5 anti-human CD338 (ABCG2)
Provider product page
BioLegend - 332018
Antibody type
Monoclonal
Antigen
CD338 (ABCG2)
Description
CD338, known as ABCG2 (BCRP1), is a multi-drug resistance (MDR) family protein that is a member of ATP binding cassette (ABC) transporters. It is highly expressed on primitive ‘side population’ (SP) stem cells. This SP phenotype is based on the efflux of fluorescent dyes such as Rhodamine 123 and Hoechst 33342. The SP cells express low or undetectable levels of CD34.  In the bone marrow, about 0.05% population of cells displays the low fluorescence and are highly enriched for repopulating cells.  The highest levels of BCRP1 mRNA expression have been seen in KDR+ human stem cells.  The expression of ABCG2 appears to be highly conserved as it has been identified in various species.
Reactivity
Human
Host
Mouse
Conjugate
Far-Red dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -