Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN350386 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN350386, RRID:AB_10787505
- Product name
- anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the c-terminal region of human KCNJ11 (Kir6.2) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 94% identity with rat and mouse sequence.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Prevalence of permanent neonatal diabetes in Slovakia and successful replacement of insulin with sulfonylurea therapy in KCNJ11 and ABCC8 mutation carriers.
Congenital hyperinsulinism: molecular basis of a heterogeneous disease.
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis.
Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro.
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
Stanik J, Gasperikova D, Paskova M, Barak L, Javorkova J, Jancova E, Ciljakova M, Hlava P, Michalek J, Flanagan SE, Pearson E, Hattersley AT, Ellard S, Klimes I
The Journal of clinical endocrinology and metabolism 2007 Apr;92(4):1276-82
The Journal of clinical endocrinology and metabolism 2007 Apr;92(4):1276-82
Congenital hyperinsulinism: molecular basis of a heterogeneous disease.
Meissner T, Beinbrech B, Mayatepek E
Human mutation 1999;13(5):351-61
Human mutation 1999;13(5):351-61
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis.
Halushka MK, Fan JB, Bentley K, Hsie L, Shen N, Weder A, Cooper R, Lipshutz R, Chakravarti A
Nature genetics 1999 Jul;22(3):239-47
Nature genetics 1999 Jul;22(3):239-47
Sequence variations in the human Kir6.2 gene, a subunit of the beta-cell ATP-sensitive K-channel: no association with NIDDM in while Caucasian subjects or evidence of abnormal function when expressed in vitro.
Sakura H, Wat N, Horton V, Millns H, Turner RC, Ashcroft FM
Diabetologia 1996 Oct;39(10):1233-6
Diabetologia 1996 Oct;39(10):1233-6
Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor.
Inagaki N, Gonoi T, Clement JP 4th, Namba N, Inazawa J, Gonzalez G, Aguilar-Bryan L, Seino S, Bryan J
Science (New York, N.Y.) 1995 Nov 17;270(5239):1166-70
Science (New York, N.Y.) 1995 Nov 17;270(5239):1166-70
No comments: Submit comment
No validations: Submit validation data