Antibody data
- Antibody Data
- Antigen structure
- References [40]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
Reference
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- Product number
- 55014-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55014-1-AP, RRID:AB_10858484
- Product name
- p75NTR antibody
- Antibody type
- Polyclonal
- Description
- p75NTR antibody (Cat. #55014-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Small extracellular vesicles derived from hair follicle neural crest stem cells enhance perineurial cell proliferation and migration via the TGF-β/SMAD/HAS2 pathway.
Dental pulp stem cell-derived exosomes promote axonal repair in spinal cord injury by suppressing neuroinflammation and apoptosis.
Activation of Nerve Growth Factor signaling limits the response to lenvatinib in hepatocellular carcinoma.
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Single cell deciphering of pruritic keloids: the interaction between fibroblasts and Schwann cells through the Midkine signaling.
Lacking TRPA1 Cation Channel Impairs Primary Closure of a Stromal Incision Injury in a Mouse Cornea.
Bioactive Silk Sericin/Bioceramic Nerve Guidance Conduit for Effective Repair of Long-Gap Transected Peripheral Nerve Injury through Regulating Schwann Cells.
MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway.
Fabrication of GDNF-Gel/HA-Mg nerve conduit and its role in repairing peripheral nerve defects.
Jiawei Kongsheng Zhenzhong Pill (JKZP) Alleviates Chronic Cerebral Hypoperfusion-Induced Hippocampal Synaptic Damage via S100A10/tPA/BDNF Pathway.
A Rapid Method to Immortalize Schwann Cells.
TAK-242 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TLR4/NF-κB pathway in rat experimental autoimmune neuritis.
Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development.
Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats.
RAD21 deficiency drives corneal to scleral differentiation fate switching via upregulating WNT9B.
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Early Clinical Outcomes of the First Commercialized Human Autologous Ex Vivo Cultivated Oral Mucosal Epithelial Cell Transplantation for Limbal Stem Cell Deficiency: Two Case Reports and Literature Review.
Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus.
Identification of the Main Chemical constituents and mechanism of Renshen Guben oral liquid against Renal Fibrosis.
Exosomes from Hair Follicle Epidermal Neural Crest Stem Cells Promote Acellular Nerve Allografts to Bridge Rat Facial Nerve Defects.
LMO1 Plays an Oncogenic Role in Human Glioma Associated With NF-kB Pathway.
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome.
Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation.
Sox10 Is a Specific Biomarker for Neural Crest Stem Cells in Immunohistochemical Staining in Wistar Rats.
MESP2 variants contribute to conotruncal heart defects by inhibiting cardiac neural crest cell proliferation.
Polydopamine/carboxylic graphene oxide-composited polypyrrole films for promoting adhesion and alignment of Schwann cells.
Prolactin (PRL), placenta growth factor (PIGF) and nerve growth factor receptor (NGFR) as biomarkers for early diagnosis and prognosis in patients with esophageal squamous cell carcinoma (ESCC).
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
NT3(P75-2) gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model.
An oleanolic acid derivative reduces denervation-induced muscle atrophy via activation of CNTF-mediated JAK2/STAT3 signaling pathway.
Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.
Astaxanthin Ameliorates Ischemic-Hypoxic-Induced Neurotrophin Receptor p75 Upregulation in the Endothelial Cells of Neonatal Mouse Brains.
CXCR4 regulates Plasmodium development in mouse and human hepatocytes.
PGC-1α-FNDC5-BDNF signaling pathway in skeletal muscle confers resilience to stress in mice subjected to chronic social defeat.
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Relevance of meniscal cell regional phenotype to tissue engineering.
Feasibility of Diffusion Tensor Imaging for Assessing Functional Recovery in Rats with Olfactory Ensheathing Cell Transplantation After Contusive Spinal Cord Injury (SCI).
Conditioned medium of olfactory ensheathing cells promotes the functional recovery and axonal regeneration after contusive spinal cord injury.
Effects of different sera conditions on olfactory ensheathing cells in vitro.
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Neural regeneration research 2026 May 1;21(5):2060-2072
Neural regeneration research 2026 May 1;21(5):2060-2072
Dental pulp stem cell-derived exosomes promote axonal repair in spinal cord injury by suppressing neuroinflammation and apoptosis.
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Tissue & cell 2026 Feb;98:103175
Tissue & cell 2026 Feb;98:103175
Activation of Nerve Growth Factor signaling limits the response to lenvatinib in hepatocellular carcinoma.
Xu M, Zheng Y, Zhao L, Wang S, Chen J, Fu Z, Ma A, Liang B, Huang Y, Xu H, Wang Y, Ai Y, Zeng H, Gao C, Cai J, Ke A, Fan J
Signal transduction and targeted therapy 2026 Apr 5;11(1)
Signal transduction and targeted therapy 2026 Apr 5;11(1)
Hsa_circ_0006834 represses intrahepatic cholangiocarcinoma proliferation through activating AMPK-mTOR pathway and autophagy via has-miR-637-NGFR network.
Wang J, Qi X, Zhao W, Hao Z, Wang K, Li Y, Wang Y, Zhang Y
PloS one 2025;20(8):e0329847
PloS one 2025;20(8):e0329847
Single cell deciphering of pruritic keloids: the interaction between fibroblasts and Schwann cells through the Midkine signaling.
Yang E, Xu R, Tu L, Zhang H, Luo S, Liang H, Liu Y, Gu S, Zhao Y, Huang X, Zan T
Burns & trauma 2025;13:tkaf057
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Lacking TRPA1 Cation Channel Impairs Primary Closure of a Stromal Incision Injury in a Mouse Cornea.
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Laboratory investigation; a journal of technical methods and pathology 2025 Sep;105(9):104193
Laboratory investigation; a journal of technical methods and pathology 2025 Sep;105(9):104193
Bioactive Silk Sericin/Bioceramic Nerve Guidance Conduit for Effective Repair of Long-Gap Transected Peripheral Nerve Injury through Regulating Schwann Cells.
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e07241
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e07241
MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway.
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Experimental hematology & oncology 2025 Mar 22;14(1):43
Experimental hematology & oncology 2025 Mar 22;14(1):43
Fabrication of GDNF-Gel/HA-Mg nerve conduit and its role in repairing peripheral nerve defects.
Cai Y, Chen Y, Li H, Wang Y, Zhang G, Liang J, Lv L, Huang Y, Zhang W, Dang X, Fang X, Wang Y
Materials today. Bio 2025 Jun;32:101764
Materials today. Bio 2025 Jun;32:101764
Jiawei Kongsheng Zhenzhong Pill (JKZP) Alleviates Chronic Cerebral Hypoperfusion-Induced Hippocampal Synaptic Damage via S100A10/tPA/BDNF Pathway.
Wu Q, Zhou Y, Ou C, Gao Z, Wu X, Zhao Y, Wang Y, Wu Z, Yu H
Brain and behavior 2025 Feb;15(2):e70328
Brain and behavior 2025 Feb;15(2):e70328
A Rapid Method to Immortalize Schwann Cells.
Zhang Y, Zheng J, Yao Y, He L, Liang S, Nan G
Pediatric discovery 2025 Dec;3(4):e70034
Pediatric discovery 2025 Dec;3(4):e70034
TAK-242 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TLR4/NF-κB pathway in rat experimental autoimmune neuritis.
Li X, Yang L, Kang X, Wang G, Yuan Y, Yang H, Yang T, Wang Z
International immunopharmacology 2025 Apr 24;153:114429
International immunopharmacology 2025 Apr 24;153:114429
Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development.
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Frontiers in pharmacology 2024;15:1366683
Frontiers in pharmacology 2024;15:1366683
Silencing p75NTR regulates osteogenic differentiation and angiogenesis of BMSCs to enhance bone healing in fractured rats.
Wu Z, Yang Y, Wang M
Journal of orthopaedic surgery and research 2024 Mar 20;19(1):192
Journal of orthopaedic surgery and research 2024 Mar 20;19(1):192
RAD21 deficiency drives corneal to scleral differentiation fate switching via upregulating WNT9B.
Liu H, Qi B, Liu G, Duan H, Li Z, Shi Z, Chen Y, Chu WK, Zhou Q, Zhang BN
iScience 2024 Jun 21;27(6):109875
iScience 2024 Jun 21;27(6):109875
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
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Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Early Clinical Outcomes of the First Commercialized Human Autologous Ex Vivo Cultivated Oral Mucosal Epithelial Cell Transplantation for Limbal Stem Cell Deficiency: Two Case Reports and Literature Review.
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International journal of molecular sciences 2023 May 18;24(10)
International journal of molecular sciences 2023 May 18;24(10)
Direct Enhancement Effect of Hippocampal Cholinergic Neurostimulating Peptide on Cholinergic Activity in the Hippocampus.
Madokoro Y, Kato D, Tsuda Y, Arakawa I, Suzuki K, Sato T, Mizuno M, Uchida Y, Ojika K, Matsukawa N
International journal of molecular sciences 2023 May 17;24(10)
International journal of molecular sciences 2023 May 17;24(10)
Identification of the Main Chemical constituents and mechanism of Renshen Guben oral liquid against Renal Fibrosis.
Zhang J, Peng J, Zhang T, Jiang H, Qin Y, Chen H, Deng X, Ren J, Wang P, Xu H
Chinese medicine 2023 May 17;18(1):56
Chinese medicine 2023 May 17;18(1):56
Exosomes from Hair Follicle Epidermal Neural Crest Stem Cells Promote Acellular Nerve Allografts to Bridge Rat Facial Nerve Defects.
Pan Y, Tang L, Dong S, Xu M, Li Q, Zhu G
Stem cells and development 2023 Jan;32(1-2):1-11
Stem cells and development 2023 Jan;32(1-2):1-11
LMO1 Plays an Oncogenic Role in Human Glioma Associated With NF-kB Pathway.
Gao L, Wu J, Wang H, Yang Y, Zheng Z, Ni B, Wang X, Peng Y, Li Y
Frontiers in oncology 2022;12:770299
Frontiers in oncology 2022;12:770299
Combined cell grafting and VPA administration facilitates neural repair through axonal regeneration and synaptogenesis in traumatic brain injury.
Liu S, Tian H, Niu Y, Yu C, Xie L, Jin Z, Niu W, Ren J, Fu L, Yao Z
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1289-1300
Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome.
Zhang Y, Chen D, Wang D, Wang L, Weng Y, Wang H, Wu X, Wang Y
Journal of clinical medicine 2022 Sep 23;11(19)
Journal of clinical medicine 2022 Sep 23;11(19)
Lidocaine prevents breast cancer growth by targeting neuronatin to inhibit nerve fibers formation.
Li B, Xu H, He C, Zou W, Tu Y
The Journal of toxicological sciences 2021;46(7):329-339
The Journal of toxicological sciences 2021;46(7):329-339
Sox10 Is a Specific Biomarker for Neural Crest Stem Cells in Immunohistochemical Staining in Wistar Rats.
Yang LN, Huang WK, Li XL, Bai YZ, Zhang SC
Disease markers 2020;2020:8893703
Disease markers 2020;2020:8893703
MESP2 variants contribute to conotruncal heart defects by inhibiting cardiac neural crest cell proliferation.
Zhang E, Yang J, Liu Y, Hong N, Xie H, Fu Q, Li F, Chen S, Yu Y, Sun K
Journal of molecular medicine (Berlin, Germany) 2020 Jul;98(7):1035-1048
Journal of molecular medicine (Berlin, Germany) 2020 Jul;98(7):1035-1048
Polydopamine/carboxylic graphene oxide-composited polypyrrole films for promoting adhesion and alignment of Schwann cells.
Li Y, Huang Z, Pu X, Chen X, Yin G, Wang Y, Miao D, Fan J, Mu J
Colloids and surfaces. B, Biointerfaces 2020 Jul;191:110972
Colloids and surfaces. B, Biointerfaces 2020 Jul;191:110972
Prolactin (PRL), placenta growth factor (PIGF) and nerve growth factor receptor (NGFR) as biomarkers for early diagnosis and prognosis in patients with esophageal squamous cell carcinoma (ESCC).
Ai X, Zhu X, Zuo J
Translational cancer research 2020 Feb;9(2):647-656
Translational cancer research 2020 Feb;9(2):647-656
Involvement of neurotrophic signaling in doxorubicin-induced cardiotoxicity.
Liao D, Zhang C, Liu N, Cao L, Wang C, Feng Q, Yao D, Long M, Jiang P
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135
Experimental and therapeutic medicine 2020 Feb;19(2):1129-1135
NT3(P75-2) gene-modified bone mesenchymal stem cells improve neurological function recovery in mouse TBI model.
Wu K, Huang D, Zhu C, Kasanga EA, Zhang Y, Yu E, Zhang H, Ni Z, Ye S, Zhang C, Hu J, Zhuge Q, Yang J
Stem cell research & therapy 2019 Oct 24;10(1):311
Stem cell research & therapy 2019 Oct 24;10(1):311
An oleanolic acid derivative reduces denervation-induced muscle atrophy via activation of CNTF-mediated JAK2/STAT3 signaling pathway.
Cui W, Liu CX, Wang J, Zhang YC, Shen Q, Feng ZH, Wu J, Li JX
European journal of pharmacology 2019 Oct 15;861:172612
European journal of pharmacology 2019 Oct 15;861:172612
Chipmunk Brain Is Resistant to Injury from Deep Hypothermic Circulatory Arrest During Cardiopulmonary Bypass.
Jiang X, Gu T, Liu Y, Gao S, Shi E, Zhang G
Therapeutic hypothermia and temperature management 2019 Jun;9(2):118-127
Therapeutic hypothermia and temperature management 2019 Jun;9(2):118-127
Astaxanthin Ameliorates Ischemic-Hypoxic-Induced Neurotrophin Receptor p75 Upregulation in the Endothelial Cells of Neonatal Mouse Brains.
Kuo MH, Lee HF, Tu YF, Lin LH, Cheng YY, Lee HT
International journal of molecular sciences 2019 Dec 6;20(24)
International journal of molecular sciences 2019 Dec 6;20(24)
CXCR4 regulates Plasmodium development in mouse and human hepatocytes.
Bando H, Pradipta A, Iwanaga S, Okamoto T, Okuzaki D, Tanaka S, Vega-Rodríguez J, Lee Y, Ma JS, Sakaguchi N, Soga A, Fukumoto S, Sasai M, Matsuura Y, Yuda M, Jacobs-Lorena M, Yamamoto M
The Journal of experimental medicine 2019 Aug 5;216(8):1733-1748
The Journal of experimental medicine 2019 Aug 5;216(8):1733-1748
PGC-1α-FNDC5-BDNF signaling pathway in skeletal muscle confers resilience to stress in mice subjected to chronic social defeat.
Zhan G, Huang N, Li S, Hua D, Zhang J, Fang X, Yang N, Luo A, Yang C
Psychopharmacology 2018 Nov;235(11):3351-3358
Psychopharmacology 2018 Nov;235(11):3351-3358
Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways.
Dai C, Ciccotosto GD, Cappai R, Wang Y, Tang S, Hoyer D, Schneider EK, Velkov T, Xiao X
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
ACS chemical neuroscience 2018 Apr 18;9(4):824-837
Relevance of meniscal cell regional phenotype to tissue engineering.
Grogan SP, Pauli C, Lotz MK, D'Lima DD
Connective tissue research 2017 May-Jul;58(3-4):259-270
Connective tissue research 2017 May-Jul;58(3-4):259-270
Feasibility of Diffusion Tensor Imaging for Assessing Functional Recovery in Rats with Olfactory Ensheathing Cell Transplantation After Contusive Spinal Cord Injury (SCI).
Gu M, Gao Z, Li X, Zhao F, Guo L, Liu J, He X
Medical science monitor : international medical journal of experimental and clinical research 2017 Jun 17;23:2961-2971
Medical science monitor : international medical journal of experimental and clinical research 2017 Jun 17;23:2961-2971
Conditioned medium of olfactory ensheathing cells promotes the functional recovery and axonal regeneration after contusive spinal cord injury.
Gu M, Gao Z, Li X, Guo L, Lu T, Li Y, He X
Brain research 2017 Jan 1;1654(Pt A):43-54
Brain research 2017 Jan 1;1654(Pt A):43-54
Effects of different sera conditions on olfactory ensheathing cells in vitro.
Lu M, Dong J, Lu T, Lv H, Yang P, Cheng Z, Li J, Liang B, Xu J, Li H, He X
International journal of molecular sciences 2014 Dec 26;16(1):420-38
International journal of molecular sciences 2014 Dec 26;16(1):420-38
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 55014-1-AP(NGFR antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- IP Result of anti-NGFR (IP:55014-1-AP, 3ug; Detection:55014-1-AP 1:300) with mouse brain tissue lysate 5000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 55014-1-AP(NGFR antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 55014-1-AP(NGFR antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The p75NTR antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human p75NTR. This antibody recognizes human,mouse,rat antigen. The p75NTR antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.