Antibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-47965APC - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal NGFR/TNFRSF16/p75NTR Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
- Reactivity
- Human, Mouse, Rat, Feline, Rabbit, Simian
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C in the dark.
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