345102

antibody from BioLegend

Targeting: NGFR CD271, p75NTR, TNFRSF16

Western blot

Immunoprecipitation

Immunohistochemistry

Antibody data

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Validation data

Product number: 345102 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#345102, RRID:AB_1937275
Product name: Purified anti-human CD271 (NGFR)
Antibody type: Monoclonal
Antigen: WM245 melanoma cells
Description: CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Vial size: 100 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4 °C.

NGFR protein structure - 345102 shown in red.