HNRNPLL

HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]). [supplied by OMIM, Aug 2008]

Description

heterogeneous nuclear ribonucleoprotein L-like

Protein family

Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

2:p22.1 (38561978 - 38603586)

Ensembl ID

ENSG00000143889  (ver. 84.38)

Orthologs

Mouse Hnrnpll: ENSMUSG00000024095

UniProt

Q8WVV9

neXtProt

NX_Q8WVV9

Human splice variants
Mouse splice variants