14464-1-AP

antibody from Proteintech Group

Targeting: TCF7 TCF-1

Provider product page for 14464-1-AP

Western blot

ELISA

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
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Validations
Western blot [1]

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Product number: 14464-1-AP - Provider product page
Provider: Proteintech Group
Product name: TCF7 antibody
Antibody type: Polyclonal
Description: TCF7 antibody (Cat. #14464-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

TCF7 protein structure - 14464-1-AP shown in red.

Submitted references Wnt/β-Catenin Activation by iCRT3 Enhanced the Pluripotency of Bovine Expanded Pluripotent Stem Cells.

Liu D, Qu B, Wang J, Han X, Su M, Li X, Li Y, Li X
Animals : an open access journal from MDPI 2026 Feb 9;16(4)

miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway.

Sun Q, Chen W, Zhang S, Zhong X, Wu Y, Qian Y, Zhu L, Zhang T, Li W
Molecular medicine reports 2026 Apr;33(4)

Gut microbiota-derived metabolite phenylacetylglutamine inhibits the progression of prostate cancer by suppressing the Wnt/β-catenin signaling pathway.

Lv J, Jin S, Zhou Y, Fu C, Shen Y, Liu B, Li J, Li M, Zhang Y, Feng N
Frontiers in pharmacology 2025;16:1528058

Targeting BATF2-RGS2 axis reduces T-cell exhaustion and restores anti-tumor immunity.

Gu X, Gao C, Su X, Zhu Y, Fang Q, Yu J, Wang Z, Zhao D, Zhang W
Molecular cancer 2025 May 30;24(1):157

RBBP8 Is a Prognostic Biomarker Associated With Response to Immune Checkpoint Inhibitors in Advanced Gastric Cancer.

Nakashima T, Matsumoto R, Tanoue K, Nakayama C, Sameshima K, Hozaka Y, Arigami T, Matsushita D, Shimonosono M, Tsuruda Y, Sasaki K, Mataki Y, Ohtsuka T
Journal of immunotherapy (Hagerstown, Md. : 1997) 2025 May 1;48(4):147-158

TMEM176B inhibits ovarian cancer progression by regulating EMT via the Wnt/β-catenin signaling pathway.

Yan L, Song Z, Yi L, Tian C, Zhang R, Qin X, Wang X, Ren S, Ma X, Wang X, Zhao X, Wang F, Wei J, Jia X, Gu M, Yuan F, Jia D
Journal of translational medicine 2025 Mar 19;23(1):350

Correlation between TCF7 and bladder cancer and feasibility of Erlotinib targeting in bladder cancer: Molecular mechanism and expression of TCF7 recombinant protein.

Mo Z, Gai S, Qin X, Meng D, Wu J, Ya W, Sun S, Huang Q
International journal of biological macromolecules 2025 Apr;301:140438

YTHDF1 Promotes Proliferation and Inhibits Apoptosis of Gastric Cancer Cells via Upregulating TCF7 mRNA Translation.

Li Y, Guo X, Liang X, Wang Z
Frontiers in bioscience (Landmark edition) 2024 Mar 20;29(3):117

Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition.

Zhu S, Meng L, Wei P, Gu G, Duan K
Translational cancer research 2024 Jan 31;13(1):348-362

The transcriptional cofactor Tle3 reciprocally controls effector and central memory CD8(+) T cell fates.

Zhao X, Hu W, Park SR, Zhu S, Hu SS, Zang C, Peng W, Shan Q, Xue HH
Nature immunology 2024 Feb;25(2):294-306

Increased Wnt5a/ROR2 signaling is associated with chondrogenesis in meniscal degeneration.

Inoue Y, Kumagai K, Ishikawa K, Kato I, Kusaba Y, Naka T, Nagashima K, Choe H, Ike H, Kobayashi N, Inaba Y
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Aug;42(8):1880-1889

DNA hypo-methylation and expression of GBP4 induces T cell exhaustion in pancreatic cancer.

Tasiheng Y, Lin X, Wang X, Zou X, Chen Y, Yan Y, Ma M, Dai Z, Wang X, Yu X, Cheng H, Liu C
Cancer immunology, immunotherapy : CII 2024 Aug 7;73(10):208

Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway.

Zhu M, Han Y, Gu T, Wang R, Si X, Kong D, Zhao P, Wang X, Li J, Zhai X, Yu Z, Lu H, Li J, Huang H, Qian P
Cell reports 2024 Apr 23;43(4):114065

TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.

Li S, Wang J, Chen H, Hou J, Shen T, Li J, Zhou B, Zhang B, Liu H, Jiang DK
Molecular carcinogenesis 2023 Nov;62(11):1686-1699

TRIM27 maintains gut homeostasis by promoting intestinal stem cell self-renewal.

Wang J, Zhao D, Lei Z, Ge P, Lu Z, Chai Q, Zhang Y, Qiang L, Yu Y, Zhang X, Li B, Zhu S, Zhang L, Liu CH
Cellular & molecular immunology 2023 Feb;20(2):158-174

Hydrogel-based miR-192 delivery inhibits the development of hepatocellular carcinoma by suppressing the GSK3β/Wnt/β-catenin pathway.

Yang Q, Zhuge X, Lin W, Yu W, Zhu Y, Shi C, Shi Z
Neoplasma 2023 Aug;70(4):555-565

Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8(+) T cell exhaustion via TRIM14-IFN-β axis.

Ma X, Wang Q, Sun C, Agarwal I, Wu H, Chen J, Zhao C, Qi G, Teng Q, Yuan C, Yan S, Peng J, Li R, Song K, Zhang Q, Kong B
Cell reports 2023 Aug 29;42(8):112944

Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity.

He T, Wang S, Li S, Shen H, Hou L, Liu Y, Wei Y, Xie F, Zhang Z, Zhao Z, Mo C, Guo H, Huang Q, Zhang R, Shen D, Li B
iScience 2023 Apr 21;26(4):106289

IL-7-Treated Periodontal Ligament Cells Regulate Local Immune Homeostasis by Modulating Treg/Th17 Cell Polarization.

Yu XY, Zhang ZQ, Huang JC, Lin JY, Cai XP, Liu CF
Frontiers in medicine 2022;9:754341

Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.

Mehmood A, Althobaiti F, Zhao L, Usman M, Chen X, Alharthi F, Soliman MM, Shah AA, Murtaza MA, Nadeem M, Ranjha MMAN, Wang C
Journal of food biochemistry 2022 Oct;46(10):e14286

Forkhead Box S1 mediates epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway to regulate colorectal cancer progression.

Zhang L, Ren CF, Yang Z, Gong LB, Wang C, Feng M, Guan WX
Journal of translational medicine 2022 Jul 21;20(1):327

Tcf1-CTCF cooperativity shapes genomic architecture to promote CD8(+) T cell homeostasis.

Shan Q, Zhu S, Chen X, Liu J, Yuan S, Li X, Peng W, Xue HH
Nature immunology 2022 Aug;23(8):1222-1235

Long noncoding RNA LINC01606 protects colon cancer cells from ferroptotic cell death and promotes stemness by SCD1-Wnt/β-catenin-TFE3 feedback loop signalling.

Luo Y, Huang S, Wei J, Zhou H, Wang W, Yang J, Deng Q, Wang H, Fu Z
Clinical and translational medicine 2022 Apr;12(4):e752

Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.

Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, Leng Q, Guo Y, Jia G
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278

Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway.

Liu X, Liu C, Chen C, Sun W, Ci Y, Li Q, Song Y
OncoTargets and therapy 2020;13:3223-3235

Therapeutic effects of β-elemene via attenuation of the Wnt/β-catenin signaling pathway in cervical cancer cells.

Wang L, Zhao Y, Wu Q, Guan Y, Wu X
Molecular medicine reports 2018 Mar;17(3):4299-4306

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse thymus tissue were subjected to SDS PAGE followed by western blot with 14464-1-AP( TCF7 Antibody) at dilution of 1:600
Validation comment: WB
Appendix: 14464-1-AP.pdf

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