BS3722

antibody from Bioworld Technology, Inc

Targeting: PRKCA PKCA, PKCα

Western blot (Data presented on provider website)

Antibody Data

Product number

BS3722

Provider

Bioworld Technology, Inc

Proper citation

Bioworld Technology Cat#BS3722, RRID:AB_1914287

Product name

PKC Ï« (E653) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 620-670 of Human PKC Ï«.

Description

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (Ï«, ÉÇI, ÉÇII and ÎÛ) and novel (n) PKC isoforms (Ñ´, š÷, šø, »Ò and IJ). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC Ñ´ and š÷ are independent of Ca2+.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.