Antibody data
- Antibody Data
- Antigen structure
- References [98]
- Comments [0]
- Validations [0]
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- Product number
- 17373-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- PADI4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PADI4 antibody (Cat. #17373-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Itaconate Modulates Neutrophil Homeostasis to Ameliorate Airway Inflammation in Diesel Exhaust Particles-exacerbated Asthma via Inhibiting NETs Formation.
Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry.
Targeting peptidyl-arginine deiminase 4 suppresses SARS-CoV-2 replication and modulates the inflammatory response.
Overexpression of Soluble Fibrinogen-like Protein 2 in MSCs Ameliorates Renal Ischemia-Reperfusion Injury in Mice by Modulating Neutrophils.
Ezrin, radixin, and moesin are novel citrullinated proteins in the decidua during pregnancy†.
Targeting the TLR4/PAD4-mediated formation of macrophage extracellular traps by curcumin attenuates plaque destabilization in ulcerative colitis-associated atherosclerosis.
Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.
Interleukin-33 Promotes Neutrophil Extracellular Trap Formation To Aggravate Renal Ischemia-Reperfusion Injury Through ST2/PI3K/Akt and ST2/PAD4 Pathways.
Neutrophil extracellular traps induce hepatocyte pyroptosis via CCDC25 in sepsis-associated liver injury.
Inhibition of neutrophil infiltration and NETosis ameliorates sepsis-induced cardiac injury and reduces myocardial inflammation and apoptosis.
Quercetin alleviates atherosclerosis associated with reduced lysophosphatidylcholine-induced macrophage extracellular traps formation and modulation of the JNK/Sp1/PAD4 pathway.
Cl-amidine confers organ protection and improves survival in hemorrhagic shock rats via the PAD4-CitH3-NETs axis.
Suppression of Inflammation by Si Miao San in Experimental Rheumatoid Arthritis Through Modulation of the AKT/ROS/Autophagy Axis.
Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling.
S100A8/S100A9 through PAD4 activation of neutrophil extracellular traps promotes granulomatous lobular mastitis.
STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.
Anti-Peptidylarginine Deiminase 4 Autoantibodies Derived From Patients With Rheumatoid Arthritis Exert Pathogenic Effects by Activating Monocytes and Exacerbating Inflammatory Arthritis.
Er Miao San and its main components phellodendrine and atractylenolide-I exert anti-rheumatoid arthritis effects by inhibiting PAD4 and thereby reducing the formation of NETs.
Fuhu Lijie Tang treats rheumatoid arthritis through multitarget therapy from autoantigen formation to bone destruction.
High‑dose X‑ray irradiation induces NETosis via the eCIRP/TREM‑1 axis in mouse neutrophils.
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
Cancer Cell-Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA.
An oncogenotype-immunophenotype paradigm governing the myeloid landscape in genetically engineered mouse models of prostate cancer.
Targeted citrullination enables p53 binding to non-canonical sites.
Targeting Inflammation: Cytosporone B Modulates Imatinib-Driven Biochemical Alterations in Rat Heart.
Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia-Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling-Mediated Neutrophil Extracellular Traps Formation.
Elimination of a neutrophil Pad4 byproduct restores stem cell-mediated bone regeneration in hyperglycemia.
Shen Yuan Yi Qi Huo Xue capsules inhibit neutrophil NETosis by regulating the PAD4/NLRP3 signaling pathway to prevent heart failure after myocardial infarction.
Repurposing zafirlukast confers renal protection in ischemia-reperfusion injury via suppressing macrophage METosis.
Forsythiaside A Alleviates Ulcerative Colitis and Inhibits Neutrophil Extracellular Traps Formation in the Mice.
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Cardiac PDK4 promotes neutrophilic PFKL methylation and drives the innate immune response in diabetic myocardial infarction.
Quercetin protected the gut barrier in ulcerative colitis by activating aryl hydrocarbon receptor.
PADI4 facilitates stem-like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma.
Ferrostatin-1 reduces the inflammatory response of rheumatoid arthritis by decreasing the antigen presenting function of fibroblast-like synoviocytes.
C-FOS promotes the formation of neutrophil extracellular traps and the recruitment of neutrophils in lung metastasis of triple-negative breast cancer.
A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination.
Fe-Doped Carbon Dots Alleviated Rheumatoid Arthritis by Inhibiting Neutrophil NETosis and Autophagy.
Targeting PAD4: A Promising Strategy to Combat β-Cell Loss in Type 1 Diabetes.
Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets.
IDH1/MDH1 deacetylation activates the cGAS-STING pathway by promoting NETosis in acute liver failure.
Sinomenine-glycyrrhizic acid self-assembly enhanced the anti-inflammatory effect of sinomenine in the treatment of rheumatoid arthritis.
Ferroptosis Induces gut microbiota and metabolic dysbiosis in Collagen-Induced arthritis mice via PAD4 enzyme.
NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression.
S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis.
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Probing tau citrullination in Alzheimer's disease brains and mouse models of tauopathy.
Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux.
CircIRAK3 Promotes Neutrophil Extracellular Trap Formation by Improving the Stability of ELANE mRNA in Sepsis.
Integration analysis of transcriptomics revealed NETosis heterogeneity and Ncf1 as a prognostic biomarker in neutrophil asthma.
PAD2 disturbs cardiomyocyte calcium homeostasis by citrullinating SERCA2a protein in hemorrhagic shock induced arrhythmia.
Down-regulation of SHP2 promotes neutrophil autophagy and inhibits neutrophil extracellular trap formation to alleviate asthma through the ERK5 pathway.
Peptide BG From Bitter Gourd (Momordica Charantia) Improves Adjuvant-Induced Arthritis by Modulating the Necroptosis/Neutrophil Extracellular Traps/Inflammation Axis and the Gut Microbiota.
Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.
Colchicine prevents perioperative myocardial injury in cardiac surgery by inhibiting the formation of neutrophil extracellular traps: evidence from rat models.
Exploration of novel human neutrophil elastase inhibitors from natural compounds: Virtual screening, in vitro, molecular dynamics simulation and in vivo study.
Dihydroartemisinin is an inhibitor of trained immunity through Akt/mTOR/HIF1α signaling pathway.
Reciprocal regulation of protein arginine deiminase 2 and 4 expression in the colonic mucosa of ulcerative colitis.
SHED-exos promote saliva secretion by suppressing p-ERK1/2-mediated apoptosis in glandular cells.
Salmonella spvC gene suppresses macrophage/neutrophil antibacterial defense mediated by gasdermin D.
IDH1/MDH1 deacetylation promotes acute liver failure by regulating NETosis.
Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats.
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.
Targeting PADI2 as a potential therapeutic strategy against metastasis in oral cancer via suppressing EMT-mediated migration and invasion and CCL3/5-induced angiogenesis.
Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway.
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Effects of the N-Butanol Extract of Pulsatilla Decoction on Neutrophils in a Mouse Model of Ulcerative Colitis.
The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression.
The role of protein arginine deiminase 4-dependent neutrophil extracellular traps formation in ulcerative colitis.
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Small molecule activates citrullination through targeting PAD2.
Sinomenine ameliorates adjuvant-induced arthritis by inhibiting the autophagy/NETosis/inflammation axis.
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Voluntary Exercise-Mediated Protection in TNBS-Induced Rat Colitis: The Involvement of NETosis and Prdx Antioxidants.
Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis.
Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities.
FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis.
Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.
Neutrophil Extracellular Traps may be a Potential Target for Treating Early Brain Injury in Subarachnoid Hemorrhage.
Inhibition of PAD4-mediated NET formation by cl-amidine prevents diabetes development in nonobese diabetic mice.
Extracellular trap can be trained as a memory response.
TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps via Interaction With SYK in Experimental Subarachnoid Hemorrhage.
Neutrophil Extracellular Traps Caused by Gut Leakage Trigger the Autoimmune Response in Nonobese Diabetic Mice.
Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)-NF-κB signalling.
Investigation of H(2)S Donor Treatment on Neutrophil Extracellular Traps in Experimental Colitis.
Citrullinated inter-alpha-trypsin inhibitor heavy chain 4 in arthritic joints and its potential effect in the neutrophil migration.
Innate and Autoimmunity in the Pathogenesis of Inherited Retinal Dystrophy.
Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages.
IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis.
Increased Protein Citrullination as a Trigger for Resident Immune System Activation, Intraretinal Inflammation, and Promotion of Anti-retinal Autoimmunity: Intersecting Paths in Retinal Degenerations of Potential Therapeutic Relevance.
Thioredoxin Modulates Protein Arginine Deiminase 4 (PAD4)-Catalyzed Citrullination.
Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsis.
Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4).
BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway.
Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.
Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice.
Zhu G, Ye L, Song Y, Chen Y, Cai H, Abuduxukuer Z, Zhu L, Zeng Y, Zhu W, Ye D, Song Y, Wang P, Jin M, Wang J
International journal of biological sciences 2026;22(5):2603-2621
International journal of biological sciences 2026;22(5):2603-2621
Gancao decoction ameliorated senecionine-induced Hepatic Sinusoidal Obstruction Syndrome in mice by inhibiting NET formation and senecionine bioactivation in liver.
Zhang S, Yan D, Cheng S, Jin J, Cui J, Liu C, Li Y, Qiu F
Journal of ethnopharmacology 2026 May 10;362:121356
Journal of ethnopharmacology 2026 May 10;362:121356
Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry.
Indeglia A, Tang HY
STAR protocols 2026 Mar 20;7(1):104326
STAR protocols 2026 Mar 20;7(1):104326
Targeting peptidyl-arginine deiminase 4 suppresses SARS-CoV-2 replication and modulates the inflammatory response.
Pasquero S, Penna A, Signorini L, Villani S, Gugliesi F, Caneparo V, Favero F, Camille W, Green RM, Frasson I, Tosi A, Genova B, Pietà AD, Verin R, Tomasoni S, Del Grosso E, Delbue S, Richter SN, Thompson PR, Rosato A, De Andrea M
iScience 2026 Mar 20;29(3):115038
iScience 2026 Mar 20;29(3):115038
Overexpression of Soluble Fibrinogen-like Protein 2 in MSCs Ameliorates Renal Ischemia-Reperfusion Injury in Mice by Modulating Neutrophils.
Chen GS, Xiong WH, Li DZ, Zhang PH, Wang YT, Zhang YC, Qi F
Balkan medical journal 2026 Mar 2;43(3):136-150
Balkan medical journal 2026 Mar 2;43(3):136-150
Ezrin, radixin, and moesin are novel citrullinated proteins in the decidua during pregnancy†.
Yamashita K, Ito S, Satoh J, Takaori-Kondo A, Mizugishi K
Biology of reproduction 2026 Mar 16;114(3):1018-1029
Biology of reproduction 2026 Mar 16;114(3):1018-1029
Targeting the TLR4/PAD4-mediated formation of macrophage extracellular traps by curcumin attenuates plaque destabilization in ulcerative colitis-associated atherosclerosis.
Li X, Qiu T, Wei Y, Li Q, Qiu J, Du R
International immunopharmacology 2026 Jun 15;179:116616
International immunopharmacology 2026 Jun 15;179:116616
Berberine inhibits protein citrullination of fibroblast-like synoviocytes by suppressing autophagy via STAT3/PAD4 pathway.
Song YN, Zhang F, He Y, Li YH, Hu FY, Gao Y, Zong SY, Wang Y, Gao XY, Tang Q, Jiang XM, Tong FZ, Yan LP, Wei F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157706
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jan;150:157706
Interleukin-33 Promotes Neutrophil Extracellular Trap Formation To Aggravate Renal Ischemia-Reperfusion Injury Through ST2/PI3K/Akt and ST2/PAD4 Pathways.
Zhang F, Wu J, Li Z, Gan L, Cao H, Chen C, Sun Z, Zhang J, Li H, Zhang X, Wang W
Inflammation 2026 Jan 20;49(1):56
Inflammation 2026 Jan 20;49(1):56
Neutrophil extracellular traps induce hepatocyte pyroptosis via CCDC25 in sepsis-associated liver injury.
Li Z, Xiao Y, Yang L, Liang F, Xu H, Gao F
International immunopharmacology 2026 Jan 15;169:115991
International immunopharmacology 2026 Jan 15;169:115991
Inhibition of neutrophil infiltration and NETosis ameliorates sepsis-induced cardiac injury and reduces myocardial inflammation and apoptosis.
Xue J, Ren Y, Chen Y, Zhu H, Wang Y
International immunopharmacology 2026 Jan 1;168(Pt 1):115862
International immunopharmacology 2026 Jan 1;168(Pt 1):115862
Quercetin alleviates atherosclerosis associated with reduced lysophosphatidylcholine-induced macrophage extracellular traps formation and modulation of the JNK/Sp1/PAD4 pathway.
Liang N, Ying L, Huang X, Wei Z, Su Y, Yang S, Luo G, Xiao L
The Journal of nutritional biochemistry 2026 Aug;154:110358
The Journal of nutritional biochemistry 2026 Aug;154:110358
Cl-amidine confers organ protection and improves survival in hemorrhagic shock rats via the PAD4-CitH3-NETs axis.
Yun H, Chi Y, Wei B, Bai H, Cao W, Zhang Z, Zhang Y, Zhang Q, Duan H
PloS one 2025;20(7):e0327085
PloS one 2025;20(7):e0327085
Suppression of Inflammation by Si Miao San in Experimental Rheumatoid Arthritis Through Modulation of the AKT/ROS/Autophagy Axis.
Zhang H, Jiang H, Wei Q, Xu J, Zhao Z, Sun Y, Lu Q
Journal of inflammation research 2025;18:9459-9476
Journal of inflammation research 2025;18:9459-9476
Kuiyangling Enema Alleviates Ulcerative Colitis Mice by Reducing Levels of Intestinal NETs and Promoting HuR/VDR Signaling.
Zhang D, Zhu Z, He Z, Duan S, Yi Q, Qiu M, Dai X, Su G, Li K, Xu L, Liu D, Wu Y, Gao Y, Li R, Guo S
Journal of inflammation research 2025;18:381-403
Journal of inflammation research 2025;18:381-403
S100A8/S100A9 through PAD4 activation of neutrophil extracellular traps promotes granulomatous lobular mastitis.
Zhu T, Yu H, Wang W, Sun Y, Wang S, Ma D, Yao Y
Frontiers in immunology 2025;16:1672538
Frontiers in immunology 2025;16:1672538
STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.
Huang R, Chen R, Xing L, Wu L, Zhu W, Jing J, Zhou T, Wu Y, Zhang S, You Z
Frontiers in immunology 2025;16:1598902
Frontiers in immunology 2025;16:1598902
Anti-Peptidylarginine Deiminase 4 Autoantibodies Derived From Patients With Rheumatoid Arthritis Exert Pathogenic Effects by Activating Monocytes and Exacerbating Inflammatory Arthritis.
Won T, Naik P, Wood MK, Wang H, Talor MV, Shi J, Bracamonte-Baran W, Thomas MA, Jaime CM, Jo W, Ray S, Foss CA, Andrade F, Čiháková D, Darrah E
Arthritis & rheumatology (Hoboken, N.J.) 2025 Sep;77(9):1150-1165
Arthritis & rheumatology (Hoboken, N.J.) 2025 Sep;77(9):1150-1165
Er Miao San and its main components phellodendrine and atractylenolide-I exert anti-rheumatoid arthritis effects by inhibiting PAD4 and thereby reducing the formation of NETs.
Tang R, Qin ZF, Yin JH, Wang JY, Su WR, Xuan ZH, Chen B, Jia XY
Fitoterapia 2025 Sep;185:106771
Fitoterapia 2025 Sep;185:106771
Fuhu Lijie Tang treats rheumatoid arthritis through multitarget therapy from autoantigen formation to bone destruction.
Yao Z, He J, Hu M, Yan P, Xu Q, Zhang Q, Lin Y, Liao J, Cai X, Liu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157086
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157086
High‑dose X‑ray irradiation induces NETosis via the eCIRP/TREM‑1 axis in mouse neutrophils.
Yamaga S, Murao A, Aziz M, Wang P, Brenner M
International journal of molecular medicine 2025 Oct;56(4)
International journal of molecular medicine 2025 Oct;56(4)
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
Wang Z, Shi R, Shi Y, Sun T, Shen Y, Wu C, Yang Y, Fan H, Wu J
Pharmacological research 2025 Oct;220:107933
Pharmacological research 2025 Oct;220:107933
Cancer Cell-Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA.
Li X, Ju Y, Xu C, Ma S, Sun L, Guo Q, Liu M, Xie Y, Min L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e07867
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(37):e07867
An oncogenotype-immunophenotype paradigm governing the myeloid landscape in genetically engineered mouse models of prostate cancer.
Zhang Y, Li Y, Gan D, Liu Y, Lu X
bioRxiv : the preprint server for biology 2025 Oct 22;
bioRxiv : the preprint server for biology 2025 Oct 22;
Targeted citrullination enables p53 binding to non-canonical sites.
Indeglia A, Valdespino A, Pantella G, Offley S, Hill C, Foster M, Casey K, Tang HY, Faustino AM, Gardini A, Murphy ME
Molecular cell 2025 Oct 2;85(19):3588-3604.e11
Molecular cell 2025 Oct 2;85(19):3588-3604.e11
Targeting Inflammation: Cytosporone B Modulates Imatinib-Driven Biochemical Alterations in Rat Heart.
Börzsei D, Nagy A, Kiss V, Virág Z, Kis G, Almási N, Török S, Veszelka M, Varga C, Szabó R
International journal of molecular sciences 2025 Oct 15;26(20)
International journal of molecular sciences 2025 Oct 15;26(20)
Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia-Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling-Mediated Neutrophil Extracellular Traps Formation.
Tian H, Xiong Y, Zhan J, Lu Z, Zhang Y, Leng Y, Huang Q, Xia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09952
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(44):e09952
Elimination of a neutrophil Pad4 byproduct restores stem cell-mediated bone regeneration in hyperglycemia.
Zhang L, Li J, Wei X, Yang W, He W, Liu W
Nature communications 2025 Nov 28;16(1):11720
Nature communications 2025 Nov 28;16(1):11720
Shen Yuan Yi Qi Huo Xue capsules inhibit neutrophil NETosis by regulating the PAD4/NLRP3 signaling pathway to prevent heart failure after myocardial infarction.
Lian YJ, Zhang HY, Liu HX, Shang JJ, Lai XL, Xing WL, Li SN
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157462
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157462
Repurposing zafirlukast confers renal protection in ischemia-reperfusion injury via suppressing macrophage METosis.
Ye X, Dong Y, Han J, Huang Y, Wen M, Zheng R, Wang P, Chen R, Zhao L
International immunopharmacology 2025 Nov 14;165:115459
International immunopharmacology 2025 Nov 14;165:115459
Forsythiaside A Alleviates Ulcerative Colitis and Inhibits Neutrophil Extracellular Traps Formation in the Mice.
Wang Z, Yan W, Lin X, Qin G, Li K, Jiang L, Li X, Xiao X, Luo T, Hou Y
Phytotherapy research : PTR 2025 May;39(5):2165-2179
Phytotherapy research : PTR 2025 May;39(5):2165-2179
Pad2 deletion induces anxiety‑like behaviors and memory deficits in mice.
Lv X, Deng H, Li C, Gao W, Zhang Y, Gao Y, Zhao B, Shi C, Gao J, Liu Z
Brain research bulletin 2025 May;224:111327
Brain research bulletin 2025 May;224:111327
Cardiac PDK4 promotes neutrophilic PFKL methylation and drives the innate immune response in diabetic myocardial infarction.
Yang S, Yan L, Chen L, Su G, Yang L, Gong L, Liu L
Pharmacological research 2025 May;215:107731
Pharmacological research 2025 May;215:107731
Quercetin protected the gut barrier in ulcerative colitis by activating aryl hydrocarbon receptor.
Wei Q, Jiang H, Zeng J, Xu J, Zhang H, Xiao E, Lu Q, Huang G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156633
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156633
PADI4 facilitates stem-like properties and cisplatin resistance through upregulating PRMT2/IDs family in oesophageal squamous cell carcinoma.
Wang Z, Wu H, Li Z, Chen Z, Feng A, Chu Y, Fang K, Zhang Z, Zhao Z, Leng Z, Zhang S, Wang X, He L, Chen T, Xu M
Clinical and translational medicine 2025 Mar;15(3):e70272
Clinical and translational medicine 2025 Mar;15(3):e70272
Ferrostatin-1 reduces the inflammatory response of rheumatoid arthritis by decreasing the antigen presenting function of fibroblast-like synoviocytes.
Zhu X, Lu H, Jia H, Wei X, Xue J, Li W, Zhang J, Wang Y, Yan J, Sun H, Ge Y, Zhang Z
Journal of translational medicine 2025 Mar 6;23(1):280
Journal of translational medicine 2025 Mar 6;23(1):280
C-FOS promotes the formation of neutrophil extracellular traps and the recruitment of neutrophils in lung metastasis of triple-negative breast cancer.
Yan S, Zhao W, Du J, Teng L, Yu T, Xu P, Liu J, Yang R, Dong Y, Wang H, Lu L, Tao W
Journal of experimental & clinical cancer research : CR 2025 Mar 28;44(1):108
Journal of experimental & clinical cancer research : CR 2025 Mar 28;44(1):108
A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination.
Li L, Jiao Q, Yang Q, Lu H, Zhou X, Zhang Q, Zhang F, Li H, Tian Z, Zeng Z
Immunity 2025 Mar 11;58(3):568-584.e6
Immunity 2025 Mar 11;58(3):568-584.e6
Fe-Doped Carbon Dots Alleviated Rheumatoid Arthritis by Inhibiting Neutrophil NETosis and Autophagy.
Wang H, Yan A, Xia C, Zhang Y, Zhou Y, Huang H, Gong X, Yuan K, Huang G
ACS biomaterials science & engineering 2025 Jun 9;11(6):3666-3681
ACS biomaterials science & engineering 2025 Jun 9;11(6):3666-3681
Targeting PAD4: A Promising Strategy to Combat β-Cell Loss in Type 1 Diabetes.
Kang HL, Szász A, Valkusz Z, Várkonyi T, Pósa A, Kupai K
International journal of molecular sciences 2025 Jun 25;26(13)
International journal of molecular sciences 2025 Jun 25;26(13)
Macrophage extracellular traps as key mediators of scleral remodeling in myopia induced by hypoxia and activated platelets.
Feng Q, Yuan J, Hu Y, Feng C, Lin X, Liu S, Ji S, Mao X, Lin X, Cong J, Li X, Li X, Li H, Yan D, Dai J
Cell reports 2025 Jun 24;44(6):115771
Cell reports 2025 Jun 24;44(6):115771
IDH1/MDH1 deacetylation activates the cGAS-STING pathway by promoting NETosis in acute liver failure.
Wang Y, Guo J, Zhang D, Zhang X, Luo K, Gong Z
International immunopharmacology 2025 Jun 17;158:114884
International immunopharmacology 2025 Jun 17;158:114884
Sinomenine-glycyrrhizic acid self-assembly enhanced the anti-inflammatory effect of sinomenine in the treatment of rheumatoid arthritis.
Jiang H, Lu Q, Huang X, Zhang H, Zeng J, Wang M, Xu J, Yuan Z, Wei Q, Xiao E, Wang P, Huang G, Xu A
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113718
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113718
Ferroptosis Induces gut microbiota and metabolic dysbiosis in Collagen-Induced arthritis mice via PAD4 enzyme.
Zhu X, Lu H, Li W, Niu S, Xue J, Sun H, Zhang J, Zhang Z
Gene 2025 Feb 5;936:149106
Gene 2025 Feb 5;936:149106
NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression.
Xu W, Liu J, Liu Q, Xu J, Zhou L, Liang Z, Huang H, Huang B, Xiao GG, Guo J
Cell reports 2025 Feb 25;44(2):115226
Cell reports 2025 Feb 25;44(2):115226
S100A12 triggers NETosis to aggravate myocardial infarction injury via the Annexin A5-calcium axis.
Zhang X, Song H, Liu D, Cai Y, Liu Z, Zhang X, Zhao X, Zhang Y, Jing Q, Yan C, Han Y
Nature communications 2025 Feb 18;16(1):1746
Nature communications 2025 Feb 18;16(1):1746
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Zhou Z, Miao X, Shen Y, Wang P, Shi R, Fan H, Yang Y, Guo M, Wu J
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Probing tau citrullination in Alzheimer's disease brains and mouse models of tauopathy.
Liang H, Hunt JB Jr, Ma C, Kovalenko A, Calahatian J, Pedersen C, Liu H, Li J, Serrano M, Blazier D, Watler M, Rocha-Rangel P, Saunders C, Blair LJ, Breydo L, Nash K, Quadri Z, Kraemer B, Nelson P, Norris C, Abner EL, Uversky VN, Chaput D, Selenica MB, Lee DC
Acta neuropathologica 2025 Dec 5;150(1):61
Acta neuropathologica 2025 Dec 5;150(1):61
Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux.
Nie M, Lei D, Liu Z, Zeng K, Liang X, Huang P, Wang Y, Sun P, Yang H, Liu P, Nie R, Huang S, Song E, Jiang W, Li Z, Yang Y, Xia Y, Yang L
Nature cancer 2025 Aug;6(8):1400-1418
Nature cancer 2025 Aug;6(8):1400-1418
CircIRAK3 Promotes Neutrophil Extracellular Trap Formation by Improving the Stability of ELANE mRNA in Sepsis.
Lu Y, Wu H, Luo Y, Xia W, Sun D, Chen R, Miao Z, Zhang W, Yu Y, Wen A
Inflammation 2025 Aug;48(4):2503-2515
Inflammation 2025 Aug;48(4):2503-2515
Integration analysis of transcriptomics revealed NETosis heterogeneity and Ncf1 as a prognostic biomarker in neutrophil asthma.
Yan Q, Zhang M, Yang J, Ye B, Zheng W, Huang H, Liao G, Jiang Y, Zhan S, Huang X
International immunopharmacology 2025 Aug 28;161:115004
International immunopharmacology 2025 Aug 28;161:115004
PAD2 disturbs cardiomyocyte calcium homeostasis by citrullinating SERCA2a protein in hemorrhagic shock induced arrhythmia.
Gan L, Li R, Wang Q, Zhou J, Zhang M, Leng M, Zhao J, Yang F, Jia S, Huang W, Ye J, Zheng M, Wang T
The journal of trauma and acute care surgery 2025 Aug 1;99(2):219-232
The journal of trauma and acute care surgery 2025 Aug 1;99(2):219-232
Down-regulation of SHP2 promotes neutrophil autophagy and inhibits neutrophil extracellular trap formation to alleviate asthma through the ERK5 pathway.
Shi D, Huang J, Wu J
Central-European journal of immunology 2024;49(3):252-272
Central-European journal of immunology 2024;49(3):252-272
Peptide BG From Bitter Gourd (Momordica Charantia) Improves Adjuvant-Induced Arthritis by Modulating the Necroptosis/Neutrophil Extracellular Traps/Inflammation Axis and the Gut Microbiota.
Han W, Xu Y, Qimuge S, Wang C, Su X
Mediators of inflammation 2024;2024:1995952
Mediators of inflammation 2024;2024:1995952
Lipopolysaccharide in Bile Promotes the Neutrophil Extracellular Traps-Induced Gallstone Formation by Activating the Gallbladder Immune Barrier.
Yu J, Meng Z, Liu X, Zheng Y, Xue D, Hao C, Wang L
ImmunoTargets and therapy 2024;13:789-803
ImmunoTargets and therapy 2024;13:789-803
Colchicine prevents perioperative myocardial injury in cardiac surgery by inhibiting the formation of neutrophil extracellular traps: evidence from rat models.
Pan HD, Kong YR, Xu L, Liu MY, Lv ZK, Matniyaz Y, Zhang HT, Tang YX, Su WX, Jiang CY, Zhu YF, Wang DJ, Jiao XL, Pan T
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2024 Oct 1;66(4)
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2024 Oct 1;66(4)
Exploration of novel human neutrophil elastase inhibitors from natural compounds: Virtual screening, in vitro, molecular dynamics simulation and in vivo study.
Zhang S, Liu Y, Jin S, Xia T, Song H, Cao C, Liao Y, Pan R, Yan M, Chang Q
European journal of pharmacology 2024 Nov 5;982:176825
European journal of pharmacology 2024 Nov 5;982:176825
Dihydroartemisinin is an inhibitor of trained immunity through Akt/mTOR/HIF1α signaling pathway.
Gao Y, Liu ZZ, Zhang JB, Zhou CK, Zhang JG, Lin XQ, Yin Q, Chen W, Yang YJ
Experimental cell research 2024 May 1;438(1):114052
Experimental cell research 2024 May 1;438(1):114052
Reciprocal regulation of protein arginine deiminase 2 and 4 expression in the colonic mucosa of ulcerative colitis.
Otsuka Y, Masuta Y, Minaga K, Okai N, Hara A, Takada R, Masaki S, Kamata K, Honjo H, Yamashita K, Kudo M, Watanabe T
Journal of clinical biochemistry and nutrition 2024 Jul;75(1):46-53
Journal of clinical biochemistry and nutrition 2024 Jul;75(1):46-53
SHED-exos promote saliva secretion by suppressing p-ERK1/2-mediated apoptosis in glandular cells.
Chu WX, Ding C, Du ZH, Wei P, Wang YX, Ge XJ, Yu GY
Oral diseases 2024 Jul;30(5):3066-3080
Oral diseases 2024 Jul;30(5):3066-3080
Salmonella spvC gene suppresses macrophage/neutrophil antibacterial defense mediated by gasdermin D.
Zhou L, Li Y, You J, Wu C, Zuo L, Chen Y, Kang L, Zhou Z, Huang R, Wu S
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jan;73(1):19-33
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jan;73(1):19-33
IDH1/MDH1 deacetylation promotes acute liver failure by regulating NETosis.
Wang Y, Shi C, Guo J, Zhang D, Zhang Y, Zhang L, Gong Z
Cellular & molecular biology letters 2024 Jan 3;29(1):8
Cellular & molecular biology letters 2024 Jan 3;29(1):8
Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats.
Mead AJ, Ahluwalia K, Ebright B, Zhang Z, Dave P, Li Z, Zhou E, Naik AA, Ngu R, Chester C, Lu A, Asante I, Pollalis D, Martinez JC, Humayun M, Louie S
International journal of molecular sciences 2024 Feb 15;25(4)
International journal of molecular sciences 2024 Feb 15;25(4)
hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50.
Osei-Amponsa V, Chandravanshi M, Lu X, Magidson V, Das S, Andresson T, Dyba M, Sabbasani VR, Swenson RE, Fromont C, Shrestha B, Zhao Y, Clapp ME, Chari R, Walters KJ
Molecular cell 2024 Feb 1;84(3):522-537.e8
Molecular cell 2024 Feb 1;84(3):522-537.e8
Targeting PADI2 as a potential therapeutic strategy against metastasis in oral cancer via suppressing EMT-mediated migration and invasion and CCL3/5-induced angiogenesis.
Hung SK, Yu CC, Lin HY, Chiou WY, Lee MS, Lin RI, Lu MC
Clinical & experimental metastasis 2024 Dec;41(6):925-935
Clinical & experimental metastasis 2024 Dec;41(6):925-935
Neutrophil extracellular traps induce barrier dysfunction in DSS-induced ulcerative colitis via the cGAS-STING pathway.
Sun T, Wang P, Zhai X, Wang Z, Miao X, Yang Y, Wu J
International immunopharmacology 2024 Dec 25;143(Pt 1):113358
International immunopharmacology 2024 Dec 25;143(Pt 1):113358
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy.
Wang Y, Guo J, Zhang D, Shi C, Zhang X, Gong Z
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
International immunopharmacology 2024 Dec 25;143(Pt 1):113270
Effects of the N-Butanol Extract of Pulsatilla Decoction on Neutrophils in a Mouse Model of Ulcerative Colitis.
Wang Y, Wu H, Sun J, Li C, Fang Y, Shi G, Ma K, Wu D, Shao J, Song H, Wang T, Wang C
Pharmaceuticals (Basel, Switzerland) 2024 Aug 16;17(8)
Pharmaceuticals (Basel, Switzerland) 2024 Aug 16;17(8)
The m6A methyltransferase METTL5 promotes neutrophil extracellular trap network release to regulate hepatocellular carcinoma progression.
Wang Q, Huang Y, Zhu Y, Zhang W, Wang B, Du X, Dai Q, Zhang F, Fang Z
Cancer medicine 2024 Apr;13(7):e7165
Cancer medicine 2024 Apr;13(7):e7165
The role of protein arginine deiminase 4-dependent neutrophil extracellular traps formation in ulcerative colitis.
Wang P, Liu D, Zhou Z, Liu F, Shen Y, You Q, Lu S, Wu J
Frontiers in immunology 2023;14:1144976
Frontiers in immunology 2023;14:1144976
Fasting-mimicking diet alleviates inflammatory pain by inhibiting neutrophil extracellular traps formation and neuroinflammation in the spinal cord.
Li T, Yue Y, Ma Y, Zhong Z, Guo M, Zhang J, Wang Z, Miao C
Cell communication and signaling : CCS 2023 Sep 21;21(1):250
Cell communication and signaling : CCS 2023 Sep 21;21(1):250
Small molecule activates citrullination through targeting PAD2.
Zhang X, Shen M, Zhu H, Zhang J, Yang M, Su K, Zhang Y, Fu W, Ke X, Qu Y
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220248
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2023 Nov 20;378(1890):20220248
Sinomenine ameliorates adjuvant-induced arthritis by inhibiting the autophagy/NETosis/inflammation axis.
Jiang H, Lu Q, Xu J, Huo G, Cai Y, Geng S, Xu H, Zhang J, Li H, Yuan K, Huang G
Scientific reports 2023 Mar 9;13(1):3933
Scientific reports 2023 Mar 9;13(1):3933
An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.
Indeglia A, Leung JC, Miller SA, Leu JI, Dougherty JF, Clarke NL, Kirven NA, Shao C, Ke L, Lovell S, Barnoud T, Lu DY, Lin C, Kannan T, Battaile KP, Yang THL, Batista Oliva I, Claiborne DT, Vogel P, Liu L, Liu Q, Nefedova Y, Cassel J, Auslander N, Kossenkov AV, Karanicolas J, Murphy ME
Cancer discovery 2023 Jul 7;13(7):1696-1719
Cancer discovery 2023 Jul 7;13(7):1696-1719
Voluntary Exercise-Mediated Protection in TNBS-Induced Rat Colitis: The Involvement of NETosis and Prdx Antioxidants.
Almási N, Török S, Al-Awar A, Veszelka M, Király L, Börzsei D, Szabó R, Varga C
Antioxidants (Basel, Switzerland) 2023 Jul 30;12(8)
Antioxidants (Basel, Switzerland) 2023 Jul 30;12(8)
Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis.
Han Y, Tomita T, Kato M, Ashihara N, Higuchi Y, Matoba H, Wang W, Hayashi H, Itoh Y, Takahashi S, Kurita H, Nakayama J, Okumura N, Hiratsuka S
Nature communications 2023 Aug 24;14(1):4960
Nature communications 2023 Aug 24;14(1):4960
Tetrandrine Ameliorates Rheumatoid Arthritis in Mice by Alleviating Neutrophil Activities.
Lu Q, Jiang H, Zhu Q, Xu J, Cai Y, Huo G, Yuan K, Huang G, Xu A
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8589121
Evidence-based complementary and alternative medicine : eCAM 2022;2022:8589121
FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis.
Li X, Gao Q, Wu W, Hai S, Hu J, You J, Huang D, Wang H, Wu D, Han M, Xi D, Yan W, Chen T, Luo X, Ning Q, Wang X
Cellular and molecular gastroenterology and hepatology 2022;14(5):1077-1101
Cellular and molecular gastroenterology and hepatology 2022;14(5):1077-1101
Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.
He W, Xi Q, Cui H, Zhang P, Huang R, Wang T, Wang D
Frontiers in pharmacology 2022;13:1022985
Frontiers in pharmacology 2022;13:1022985
Neutrophil Extracellular Traps may be a Potential Target for Treating Early Brain Injury in Subarachnoid Hemorrhage.
Zeng H, Fu X, Cai J, Sun C, Yu M, Peng Y, Zhuang J, Chen J, Chen H, Yu Q, Xu C, Zhou H, Cao Y, Hu L, Li J, Cao S, Gu C, Yan F, Chen G
Translational stroke research 2022 Feb;13(1):112-131
Translational stroke research 2022 Feb;13(1):112-131
Inhibition of PAD4-mediated NET formation by cl-amidine prevents diabetes development in nonobese diabetic mice.
Shen Y, You Q, Wu Y, Wu J
European journal of pharmacology 2022 Feb 5;916:174623
European journal of pharmacology 2022 Feb 5;916:174623
Extracellular trap can be trained as a memory response.
Gao Y, Zhang JG, Liu ZZ, Ma K, Lin XQ, Zhang JB, Chen W, Yang YJ
Virulence 2022 Dec;13(1):471-482
Virulence 2022 Dec;13(1):471-482
TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps via Interaction With SYK in Experimental Subarachnoid Hemorrhage.
Wu X, Zeng H, Xu C, Chen H, Fan L, Zhou H, Yu Q, Fu X, Peng Y, Yan F, Yu X, Chen G
Frontiers in immunology 2021;12:766178
Frontiers in immunology 2021;12:766178
Neutrophil Extracellular Traps Caused by Gut Leakage Trigger the Autoimmune Response in Nonobese Diabetic Mice.
You Q, Shen Y, Wu Y, Li Y, Liu C, Huang F, Gu HF, Wu J
Frontiers in immunology 2021;12:711423
Frontiers in immunology 2021;12:711423
Neutrophil elastase promotes neointimal hyperplasia by targeting toll-like receptor 4 (TLR4)-NF-κB signalling.
Yang M, Chen Q, Mei L, Wen G, An W, Zhou X, Niu K, Liu C, Ren M, Sun K, Xiao Q, Zhang L
British journal of pharmacology 2021 Oct;178(20):4048-4068
British journal of pharmacology 2021 Oct;178(20):4048-4068
Investigation of H(2)S Donor Treatment on Neutrophil Extracellular Traps in Experimental Colitis.
Török S, Almási N, Valkusz Z, Pósa A, Varga C, Kupai K
International journal of molecular sciences 2021 Nov 25;22(23)
International journal of molecular sciences 2021 Nov 25;22(23)
Citrullinated inter-alpha-trypsin inhibitor heavy chain 4 in arthritic joints and its potential effect in the neutrophil migration.
Osada A, Matsumoto I, Mikami N, Ohyama A, Kurata I, Kondo Y, Tsuboi H, Ishigami A, Sano Y, Arai T, Ise N, Sumida T
Clinical and experimental immunology 2021 Mar;203(3):385-399
Clinical and experimental immunology 2021 Mar;203(3):385-399
Innate and Autoimmunity in the Pathogenesis of Inherited Retinal Dystrophy.
Hollingsworth TJ, Gross AK
Cells 2020 Mar 5;9(3)
Cells 2020 Mar 5;9(3)
Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages.
Trimova G, Yamagata K, Iwata S, Hirata S, Zhang T, Uemura F, Satoh M, Biln N, Nakayamada S, Maksymowych WP, Tanaka Y
Arthritis research & therapy 2020 Feb 12;22(1):24
Arthritis research & therapy 2020 Feb 12;22(1):24
IL-6-PAD4 axis in the earliest phase of arthritis in knock-in gp130F759 mice, a model for rheumatoid arthritis.
Yahagi A, Saika T, Hirano H, Takai-Imamura M, Tsuji F, Aono H, Iseki M, Morita Y, Igarashi H, Saeki Y, Ishihara K
RMD open 2019;5(2):e000853
RMD open 2019;5(2):e000853
Increased Protein Citrullination as a Trigger for Resident Immune System Activation, Intraretinal Inflammation, and Promotion of Anti-retinal Autoimmunity: Intersecting Paths in Retinal Degenerations of Potential Therapeutic Relevance.
Iannaccone A, Radic MZ
Advances in experimental medicine and biology 2019;1185:175-179
Advances in experimental medicine and biology 2019;1185:175-179
Thioredoxin Modulates Protein Arginine Deiminase 4 (PAD4)-Catalyzed Citrullination.
Nagar M, Tilvawala R, Thompson PR
Frontiers in immunology 2019;10:244
Frontiers in immunology 2019;10:244
Cold-inducible RNA-binding Protein Induces Neutrophil Extracellular Traps in the Lungs during Sepsis.
Ode Y, Aziz M, Jin H, Arif A, Nicastro JG, Wang P
Scientific reports 2019 Apr 18;9(1):6252
Scientific reports 2019 Apr 18;9(1):6252
Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Zhao JY, Duan XL, Yang L, Liu JP, He YT, Guo Z, Hu XD, Suo ZW
Neuroscience 2018 Sep 15;388:1-10
Neuroscience 2018 Sep 15;388:1-10
Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4).
Hollingsworth TJ, Radic MZ, Beranova-Giorgianni S, Giorgianni F, Wang Y, Iannaccone A
Investigative ophthalmology & visual science 2018 Aug 1;59(10):3808-3815
Investigative ophthalmology & visual science 2018 Aug 1;59(10):3808-3815
BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway.
Ledet MM, Anderson R, Harman R, Muth A, Thompson PR, Coonrod SA, Van de Walle GR
BMC cancer 2018 Apr 12;18(1):412
BMC cancer 2018 Apr 12;18(1):412
Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase-deficient mice on 129Sv/C57BL/6 background.
Mizugishi K, Yamashita K
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5577-5591
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Dec;31(12):5577-5591
Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice.
Suzuki A, Kochi Y, Shoda H, Seri Y, Fujio K, Sawada T, Yamada R, Yamamoto K
BMC musculoskeletal disorders 2016 May 5;17:205
BMC musculoskeletal disorders 2016 May 5;17:205
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