Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 55195-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55195-1-AP, RRID:AB_10858797
- Product name
- CPSF7 antibody
- Antibody type
- Polyclonal
- Description
- CPSF7 antibody (Cat. #55195-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Mediator regulates transcriptional termination through crosstalk with pre-mRNA 3' end processing factors.
E3 ligase SYVN1-mediated polyubiquitination of CPSF6 promotes alternative polyadenylation and antivirus effects of macrophages.
2'-O-methylation at internal sites on mRNA promotes mRNA stability.
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation.
U1 snRNP proteins promote proximal alternative polyadenylation sites by directly interacting with 3' end processing core factors.
Lu C, Bai X, Zhang H, Zhang Y, Yang M, Zheng Y, Jin Z, Yang W, Guo G, Huang Q, Huang Y, Wu L, Fu XD, Zhang Z, Wang G
Molecular cell 2025 Jun 5;85(11):2147-2164.e10
Molecular cell 2025 Jun 5;85(11):2147-2164.e10
E3 ligase SYVN1-mediated polyubiquitination of CPSF6 promotes alternative polyadenylation and antivirus effects of macrophages.
Lu X, Liu C, Wu R, Hu Z, Liu S, Li X, Liu Y, Li M, Liang J, Huang Y, Han Y, Ou X, Deng K, Liang C, Chen S, Fu Y, Xu A
Cell reports 2025 Feb 25;44(2):115276
Cell reports 2025 Feb 25;44(2):115276
2'-O-methylation at internal sites on mRNA promotes mRNA stability.
Li Y, Yi Y, Gao X, Wang X, Zhao D, Wang R, Zhang LS, Gao B, Zhang Y, Zhang L, Cao Q, Chen K
Molecular cell 2024 Jun 20;84(12):2320-2336.e6
Molecular cell 2024 Jun 20;84(12):2320-2336.e6
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Ge Y, Huang J, Chen R, Fu Y, Ling T, Ou X, Rong X, Cheng Y, Lin Y, Zhou F, Lu C, Yuan S, Xu A
PLoS pathogens 2024 Feb;20(2):e1012061
PLoS pathogens 2024 Feb;20(2):e1012061
CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation.
Liu S, Wu R, Chen L, Deng K, Ou X, Lu X, Li M, Liu C, Chen S, Fu Y, Xu A
Cell reports 2023 Oct 31;42(10):113197
Cell reports 2023 Oct 31;42(10):113197
U1 snRNP proteins promote proximal alternative polyadenylation sites by directly interacting with 3' end processing core factors.
Hu Z, Li M, Huo Z, Chen L, Liu S, Deng K, Lu X, Chen S, Fu Y, Xu A
Journal of molecular cell biology 2022 Dec 26;14(8)
Journal of molecular cell biology 2022 Dec 26;14(8)
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 55195-1-AP(CPSF7 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CPSF7 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human CPSF7. This antibody recognizes human,mouse,rat antigen. The CPSF7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
