Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP1-81647 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-81647, RRID:AB_11013536
- Product name
- Rabbit Polyclonal Cytokeratin, HMW Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Cytokeratin, HMW antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Keratin 76 is required for tight junction function and maintenance of the skin barrier.
Downregulation of keratin 76 expression during oral carcinogenesis of human, hamster and mouse.
DiTommaso T, Cottle DL, Pearson HB, Schlüter H, Kaur P, Humbert PO, Smyth IM
PLoS genetics 2014 Oct;10(10):e1004706
PLoS genetics 2014 Oct;10(10):e1004706
Downregulation of keratin 76 expression during oral carcinogenesis of human, hamster and mouse.
Ambatipudi S, Bhosale PG, Heath E, Pandey M, Kumar G, Kane S, Patil A, Maru GB, Desai RS, Watt FM, Mahimkar MB
PloS one 2013;8(7):e70688
PloS one 2013;8(7):e70688
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Cytokeratin, HMW Antibody [NBP1-81647] - Staining of human skin shows positivity in keratinized layer and basal cells of epidermis.