Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN307036 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- Syn 211
- Vial size
- 100 µg
- Storage
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Submitted references Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions.
A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease.
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM
Science (New York, N.Y.) 2000 Nov 3;290(5493):985-9
Science (New York, N.Y.) 2000 Nov 3;290(5493):985-9
A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease.
Giasson BI, Jakes R, Goedert M, Duda JE, Leight S, Trojanowski JQ, Lee VM
Journal of neuroscience research 2000 Feb 15;59(4):528-33
Journal of neuroscience research 2000 Feb 15;59(4):528-33
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Supportive validation
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- Experimental details
- Extracts of SHSY-5Y human neuroblastoma cells were resolved by SDS PAGE and transferred to a PVDF membrane. Membranes were incubated with 1 ?g/mL of the anti-? synuclein antibody (Syn 211). After washing, membranes were incubated with goat F(ab?)2 anti-mouse IgG alkaline phosphatase . The membrane was then exposed to Kodak BioMax film. Human.