66412-1-Ig

antibody from Proteintech Group

Targeting: SNCA NACP, PARK1, PARK4, PD1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66412-1-Ig

Provider

Proteintech Group

Product name

Alpha Synuclein antibody

Antibody type

Monoclonal

Description

Alpha Synuclein antibody (Cat. #66412-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1B10E9

Vial size

20ul, 150ul

References

Submitted references

Activation of mitophagy via miR-223/NLRP3 axis ameliorates dopaminergic neuronal damage in parkinson's disease.

Wu Y, Fan X, Wang D, Yang H
Metabolic brain disease 2026 Mar 23;41(1)

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Reliable repurposing of the antibody interactome inside the cell.

O'Shea CM, Shahzad R, Aghasoleimani K, Newman S, Panmanee J, Schalkwyk LC, Brooke GN, Benson FE, Trimmer JS, Bosco DA, Fujisawa T, Ichijo H, Cashman NR, Engel S, Wright GSA
Nature communications 2026 Jan 31;17(1)

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DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases.

Ge R, Chen M, Wu S, Huang S, Zhou P, Cao M, Zhang F, Zang J, Zhu Y, Li J, Ni G, Yang Z, Li Q, Pan W, Zhang L, Liu M, Xuan C, Yu H, Zhou J, Xie S
Nature communications 2025 May 20;16(1):4683

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Systematic identification of SNCA as a key gene in ischemic cardiomyopathy via integrated weighted gene co-expression network analysis and experimental validation.

Zhu Y, Cao B, Huang K, Liu J
Biochemical and biophysical research communications 2025 Jul 30;772:152063

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Dopaminergic Neuron-Specific Tfam Knockout Links Inter-Organelle Miscommunication to Early-Onset Parkinsonism.

Shen W, Zheng M, Zhao Y, Ni F, Zhu X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Aug 15;39(15):e70900

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Urea cycle dysregulation drives metabolic stress and neurodegeneration in Parkinson's disease.

Zhang S, Wan G, Qiu Y, Zhang M, Deng H, Wang Q, Hu J, Gui J, Chen D, Huang B, Ran J
NPJ Parkinson's disease 2025 Aug 11;11(1):237

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The alteration of intestinal mucosal α-synuclein expression and mucosal microbiota in Parkinson's disease.

Shi J, Wang Y, Chen D, Xu X, Li W, Li K, He J, Su W, Luo Q
Applied microbiology and biotechnology 2023 Mar;107(5-6):1917-1929

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Nardosinone regulates the slc38a2 gene to alleviate Parkinson's symptoms in rats through the GABAergic synaptic and cAMP pathways.

Bian LH, Yao ZW, Wang ZY, Wang XM, Li QY, Yang X, Li JY, Wei XJ, Wan GH, Wang YQ, Shi JL, Guo JY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113269

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Regular Aerobic Exercise-Alleviated Dysregulation of CAMKIIα Carbonylation to Mitigate Parkinsonism via Homeostasis of Apoptosis With Autophagy.

Liu W, Fu R, Wang Z, Liu S, Tang C, Li L, Yin D
Journal of neuropathology and experimental neurology 2020 Jan 1;79(1):46-61