ABIN967584

antibody from antibodies-online

Targeting: SNCA NACP, PARK1, PARK4, PD1

Western blot (Data presented on provider website)

Antibody Data

Product number

ABIN967584

Provider

antibodies-online

Product name

anti-Synuclein, alpha (Non A4 Component of Amyloid Precursor) (SNCA) (Tyr125) antibody

Antibody type

Monoclonal

Antigen

Phosphorylated peptide corresponding to the region including the Tyrosine 125 residue of alpha-Synuclein

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

I57-628

Vial size

0.1 mg

Concentration

0.5 mg/ml

Storage

Store undiluted at 4°C.

References

Submitted references

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs.

Forman MS, Trojanowski JQ, Lee VM
Nature medicine 2004 Oct;10(10):1055-63

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Tyrosine 125 of alpha-synuclein plays a critical role for dimerization following nitrative stress.

Takahashi T, Yamashita H, Nakamura T, Nagano Y, Nakamura S
Brain research 2002 May 31;938(1-2):73-80

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Activation of Pyk2/RAFTK induces tyrosine phosphorylation of alpha-synuclein via Src-family kinases.

Nakamura T, Yamashita H, Nagano Y, Takahashi T, Avraham S, Avraham H, Matsumoto M, Nakamura S
FEBS letters 2002 Jun 19;521(1-3):190-4

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alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases.

Ellis CE, Schwartzberg PL, Grider TL, Fink DW, Nussbaum RL
The Journal of biological chemistry 2001 Feb 9;276(6):3879-84

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Activated Fyn phosphorylates alpha-synuclein at tyrosine residue 125.

Nakamura T, Yamashita H, Takahashi T, Nakamura S
Biochemical and biophysical research communications 2001 Feb 2;280(4):1085-92