APR00183G

antibody from Leading Biology

Targeting: SMC2 CAP-E, hCAP-E, SMC2L1

Western blot (Recommended by provider)

Antibody Data

Product number

APR00183G

Provider

Leading Biology

Product name

SMC2 Antibody

Antibody type

Polyclonal

Description

Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.