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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Immunohistochemistry [2]
- Flow cytometry [2]
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- Product number
- DDX0180P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal DCIR/CLEC4A Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references New insights into the phenotype of human dendritic cell populations.
Differentiation of human monocytes and derived subsets of macrophages and dendritic cells by the HLDA10 monoclonal antibody panel.
The Consequences of Multiple Simultaneous C-Type Lectin-Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN.
Profiling of primary peripheral blood- and monocyte-derived dendritic cells using monoclonal antibodies from the HLDA10 Workshop in Wollongong, Australia.
Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain.
Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells.
Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion.
Semi mature blood dendritic cells exist in patients with ductal pancreatic adenocarcinoma owing to inflammatory factors released from the tumor.
APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif.
Clark GJ, Kupresanin F, Fromm PD, Ju X, Muusers L, Silveira PA, Elgundi Z, Gasiorowski RE, Papadimitrious MS, Bryant C, Lee KM, Clarke CJ, Young JW, Chan A, Harman A, Botting R, Cabezón R, Benitez-Ribas D, Brooks AE, Dunbar PR, Hart DN
Clinical & translational immunology 2016 Jan;5(1):e61
Clinical & translational immunology 2016 Jan;5(1):e61
Differentiation of human monocytes and derived subsets of macrophages and dendritic cells by the HLDA10 monoclonal antibody panel.
Ohradanova-Repic A, Machacek C, Fischer MB, Stockinger H
Clinical & translational immunology 2016 Jan;5(1):e55
Clinical & translational immunology 2016 Jan;5(1):e55
The Consequences of Multiple Simultaneous C-Type Lectin-Ligand Interactions: DCIR Alters the Endo-Lysosomal Routing of DC-SIGN.
García-Vallejo JJ, Bloem K, Knippels LM, Garssen J, van Vliet SJ, van Kooyk Y
Frontiers in immunology 2015;6:87
Frontiers in immunology 2015;6:87
Profiling of primary peripheral blood- and monocyte-derived dendritic cells using monoclonal antibodies from the HLDA10 Workshop in Wollongong, Australia.
Autenrieth SE, Grimm S, Rittig SM, Grünebach F, Gouttefangeas C, Bühring HJ
Clinical & translational immunology 2015 Nov;4(11):e50
Clinical & translational immunology 2015 Nov;4(11):e50
Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain.
Bloem K, Vuist IM, van der Plas AJ, Knippels LM, Garssen J, García-Vallejo JJ, van Vliet SJ, van Kooyk Y
PloS one 2013;8(6):e66266
PloS one 2013;8(6):e66266
Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to T Cells.
Bloem K, García-Vallejo JJ, Vuist IM, Cobb BA, van Vliet SJ, van Kooyk Y
Frontiers in immunology 2013;4:103
Frontiers in immunology 2013;4:103
Targeting uptake receptors on human plasmacytoid dendritic cells triggers antigen cross-presentation and robust type I IFN secretion.
Tel J, Sittig SP, Blom RA, Cruz LJ, Schreibelt G, Figdor CG, de Vries IJ
Journal of immunology (Baltimore, Md. : 1950) 2013 Nov 15;191(10):5005-12
Journal of immunology (Baltimore, Md. : 1950) 2013 Nov 15;191(10):5005-12
Semi mature blood dendritic cells exist in patients with ductal pancreatic adenocarcinoma owing to inflammatory factors released from the tumor.
Tjomsland V, Spångeus A, Sandström P, Borch K, Messmer D, Larsson M
PloS one 2010 Oct 15;5(10):e13441
PloS one 2010 Oct 15;5(10):e13441
APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif.
Bates EE, Fournier N, Garcia E, Valladeau J, Durand I, Pin JJ, Zurawski SM, Patel S, Abrams JS, Lebecque S, Garrone P, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 1999 Aug 15;163(4):1973-83
Journal of immunology (Baltimore, Md. : 1950) 1999 Aug 15;163(4):1973-83
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DCIR/CLEC4A Antibody (111F8.04) [DDX0180P-100] - C-type lectin with a tyrosine based inhibitory motif
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: DCIR/CLEC4A Antibody (111F8.04) [DDX0180P-100] - IHC staining of human tonsil frozen section with 111F8 (X1000)
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow (Cell Surface): DCIR/CLEC4A Antibody (111F8.04) [DDX0180P-100] - Analysis using the PE conjugate of DDX0180P-100. Staining of DCIR (shaded histogram) in human PBMCs using the monocyte population gated using forward and side scatter with DDX0180PE at 1ug/ml (A) and 3 ug/ml (B). Open histogram is isotype control.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: DCIR/CLEC4A Antibody (111F8.04) [DDX0180P-100] - FACS staining of monocytederivedDCs (GM+IL4) with 111F8
