orb1467379

antibody from Biorbyt
Targeting: CLEC4A CD367, CLECSF6, DCIR, DDB27
Provider product page for orb1467379
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb1467379 - Provider product page
Provider
Biorbyt
Product name
Anti-Hu CD367 Purified
Antibody type
Monoclonal
Description
CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose, fucose, and weakly also to N-acetylglucosamine. It is expressed on dendritic cells, macrophages, monocytes, B cells, and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering, it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.
Reactivity
Human, Simian
Conjugate
Unconjugated
Antibody clone number
9E8
Vial size
0.1 mg
Concentration
1 mg/ml
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
CLEC4A protein structure - orb1467379 shown in red.