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- References [3]
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- Product number
- MAB1748 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human DCIR/CLEC4A Monoclonal Antibody (Clone 216110)
- Antibody type
- Monoclonal
- Antigen
- Mouse myeloma cell line NS0-derived recombinant human DCIR isoform 1, Gln70-Leu237
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q9UMR7- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Analysis of HLDA9 mAbs on plasmacytoid dendritic cells.
DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production.
Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production.
Cabezón R, Sintes J, Llinàs L, Benitez-Ribas D
Immunology letters 2011 Jan 30;134(2):167-73
Immunology letters 2011 Jan 30;134(2):167-73
DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production.
Meyer-Wentrup F, Cambi A, Joosten B, Looman MW, de Vries IJ, Figdor CG, Adema GJ
Journal of leukocyte biology 2009 Mar;85(3):518-25
Journal of leukocyte biology 2009 Mar;85(3):518-25
Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-alpha production.
Meyer-Wentrup F, Benitez-Ribas D, Tacken PJ, Punt CJ, Figdor CG, de Vries IJ, Adema GJ
Blood 2008 Apr 15;111(8):4245-53
Blood 2008 Apr 15;111(8):4245-53
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