10873-1-AP

antibody from Proteintech Group

Targeting: PITX1 BFT, POTX, PTX1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

10873-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10873-1-AP, RRID:AB_10859664

Product name

PITX1 antibody

Antibody type

Polyclonal

Description

PITX1 antibody (Cat. #10873-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Downregulation of MLL1 Promotes Intestinal Epithelial Barrier Repair Through Gata4/Bmp4 Activation to Ameliorate Crohn's Disease-Like Colitis in Mice.

Song X, Li J, Chen Y, Li B, Yang Y, Guan X, Zhang X, Tao L, Geng Z, Zuo L, Wang Y, Wang L, Hu J
Cell proliferation 2026 Feb 24;:e70182

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Characterizations of G-Quadruplex RNA-Protein Interactions in Living Cells.

Tang F, Liang X, Porter DF, Miao W, Maehlmann K, Yuan J, Khavari PA, Wang Y
Analytical chemistry 2026 Apr 28;98(16):12090-12098

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Spatial transcriptome analysis of the human eyelid depicts meibomian gland cell differentiation: A pilot study.

Binder H, Hampel U, Loeffler-Wirth H, Hansmann F, Pfannkuche H, Schmidt M, Schneider MR
Physiological reports 2025 Sep;13(18):e70571

---

Single-cell landscape of the tumour immune microenvironment in human gynaecologic malignancies.

Yin S, Li S, Tu M, Xu J
Clinical and translational medicine 2025 Nov;15(11):e70538

---

Consensus artificial intelligence-driven prognostic signature for predicting the prognosis of hepatocellular carcinoma: a multi-center and large-scale study.

Wen W, Wang R
NPJ precision oncology 2025 Jul 1;9(1):207

---

Identification and Verification of Key Genes Associated with Temozolomide Resistance in Glioblastoma Based on Comprehensive Bioinformatics Analysis.

Hu J, Yang J, Hu N, Shi Z, Hu T, Mi B, Wang H, Chen W
Iranian journal of biotechnology 2024 Oct;22(4):e3892

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Divergent transcriptional regulation of astrocyte reactivity across disorders.

Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV
Nature 2022 Jun;606(7914):557-564

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G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities.

He X, Yuan J, Wang Y
Nucleic acids research 2021 Nov 8;49(19):11323-11336

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Mandibular-pelvic-patellar syndrome is a novel PITX1-related disorder due to alteration of PITX1 transactivation ability.

Morel G, Duhamel C, Boussion S, Frénois F, Lesca G, Chatron N, Labalme A, Sanlaville D, Edery P, Thevenon J, Faivre L, Fassier A, Prodhomme O, Escande F, Manouvrier S, Petit F, Geneviève D, Rossi M
Human mutation 2020 Sep;41(9):1499-1506

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Paired like homeodomain 1 and SAM and SH3 domain-containing 1 in the progression and prognosis of head and neck squamous cell carcinoma.

Jin Y, Qin X
The international journal of biochemistry & cell biology 2020 Oct;127:105846

---

Proton Sensitivity of Corticotropin-Releasing Hormone Receptor 1 Signaling to Proopiomelanocortin in Male Mice.

Kameda H, Yamamoto M, Tone Y, Tone M, Melmed S
Endocrinology 2019 Feb 1;160(2):276-291

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All-trans-retinoid acid (ATRA) may have inhibited chondrogenesis of primary hind limb bud mesenchymal cells by downregulating Pitx1 expression.

Wang YG, Li XD, Liu ZY, Zhang TG, Chen B, Hou GQ, Hong Q, Xie P, Du SX
Toxicology letters 2014 Jan 13;224(2):282-9

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HeLa cells were subjected to SDS PAGE followed by western blot with 10873-1-AP(PITX1 antibody) at dilution of 1:800

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using PITX1 antibody 10873-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human tonsillitis using 10873-1-AP(PITX1 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human tonsillitis using 10873-1-AP(PITX1 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue