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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Chromatin Immunoprecipitation [1]
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- Product number
- HPA008743 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA008743, RRID:AB_1855413
- Product name
- Anti-PITX1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PITX1, Gene description: paired-like homeodomain 1, Alternative Gene Names: BFT, POTX, PTX1, Validated applications: ICC, ChIP, Uniprot ID: P78337, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references The single-cell transcriptomic atlas and RORA-mediated 3D epigenomic remodeling in driving corneal epithelial differentiation
PITX1 Is a Regulator of TERT Expression in Prostate Cancer with Prognostic Power
DNA hypermethyation and silencing ofPITX1correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma
Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse
Li M, Guo H, Wang B, Han Z, Wu S, Liu J, Huang H, Zhu J, An F, Lin Z, Mo K, Tan J, Liu C, Wang L, Deng X, Li G, Ji J, Ouyang H
Nature Communications 2024;15(1)
Nature Communications 2024;15(1)
PITX1 Is a Regulator of TERT Expression in Prostate Cancer with Prognostic Power
Poos A, Schroeder C, Jaishankar N, Röll D, Oswald M, Meiners J, Braun D, Knotz C, Frank L, Gunkel M, Spilger R, Wollmann T, Polonski A, Makrypidi-Fraune G, Fraune C, Graefen M, Chung I, Stenzel A, Erfle H, Rohr K, Baniahmad A, Sauter G, Rippe K, Simon R, Koenig R
Cancers 2022;14(5):1267
Cancers 2022;14(5):1267
DNA hypermethyation and silencing ofPITX1correlated with advanced stage and poor postoperative prognosis of esophageal squamous cell carcinoma
Otsubo T, Yamada K, Hagiwara T, Oshima K, Iida K, Nishikata K, Toyoda T, Igari T, Nohara K, Yamashita S, Hattori M, Dohi T, Kawamura Y
Oncotarget 2017;8(48):84434-84448
Oncotarget 2017;8(48):84434-84448
Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse
Chen Y, Xu H, Lin G
Cell Discovery 2017;3(1)
Cell Discovery 2017;3(1)
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli.
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-PITX1 (HPA008743, Lot 000048743) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
