Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM00353G - Provider product page
- Provider
- Leading Biology
- Product name
- PAX7 (Rhabdomyosarcoma Marker) Antibody - Without BSA and Azide
- Antibody type
- Monoclonal
- Description
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Zebrafish
- Host
- Mouse
- Antibody clone number
- PAX7/497
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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