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antibody from antibodies-online
Targeting: TRPV4
CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN351289 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN351289, RRID:AB_10782351
- Product name
- anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) (Trp12), (Cytoplasmic Loop) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the 1t cytoplasmic loop of human TRPV4 (VRL-2, VRL2, OTRPC4, TRP12) conjugated to an immunogenic carrier protein was used as the immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Trp12,Cytoplasmic Loop
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking.
Impaired pressure sensation in mice lacking TRPV4.
Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor.
Arniges M, Fernández-Fernández JM, Albrecht N, Schaefer M, Valverde MA
The Journal of biological chemistry 2006 Jan 20;281(3):1580-6
The Journal of biological chemistry 2006 Jan 20;281(3):1580-6
Impaired pressure sensation in mice lacking TRPV4.
Suzuki M, Mizuno A, Kodaira K, Imai M
The Journal of biological chemistry 2003 Jun 20;278(25):22664-8
The Journal of biological chemistry 2003 Jun 20;278(25):22664-8
Ca2+-dependent potentiation of the nonselective cation channel TRPV4 is mediated by a C-terminal calmodulin binding site.
Strotmann R, Schultz G, Plant TD
The Journal of biological chemistry 2003 Jul 18;278(29):26541-9
The Journal of biological chemistry 2003 Jul 18;278(29):26541-9
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.
Strotmann R, Harteneck C, Nunnenmacher K, Schultz G, Plant TD
Nature cell biology 2000 Oct;2(10):695-702
Nature cell biology 2000 Oct;2(10):695-702
Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor.
Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S
Cell 2000 Oct 27;103(3):525-35
Cell 2000 Oct 27;103(3):525-35
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