20987-1-AP
antibody from Proteintech Group
Targeting: TRPV4
CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC
Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 20987-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20987-1-AP, RRID:AB_10926386
- Product name
- TRPV4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TRPV4 antibody (Cat. #20987-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Decrease in AQP4 expression level in atrophied skeletal muscles with innervation.
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Exposure to both formaldehyde and high relative humidity exacerbates allergic asthma by activating the TRPV4-p38 MAPK pathway in Balb/c mice.
Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term.
The mechanosensitive ion channel TRPV4 is a regulator of lung development and pulmonary vasculature stabilization.
Expressions of TRPVs in the cholesteatoma epithelium.
Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.
Huang T, Xu T, Wang Y, Zhou Y, Yu D, Wang Z, He L, Chen Z, Zhang Y, Davidson D, Dai Y, Hang C, Liu X, Yan C
Autophagy 2021 Nov;17(11):3592-3606
Autophagy 2021 Nov;17(11):3592-3606
Decrease in AQP4 expression level in atrophied skeletal muscles with innervation.
Ishido M, Yoshikado T
Physiological reports 2021 May;9(9):e14856
Physiological reports 2021 May;9(9):e14856
TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model.
Li W, Xu Y, Liu Z, Shi M, Zhang Y, Deng Y, Zhong X, Chen L, He J, Zeng J, Luo M, Cao W, Wan W
Neuropharmacology 2021 Dec 15;201:108834
Neuropharmacology 2021 Dec 15;201:108834
Exposure to both formaldehyde and high relative humidity exacerbates allergic asthma by activating the TRPV4-p38 MAPK pathway in Balb/c mice.
Duan J, Xie J, Deng T, Xie X, Liu H, Li B, Chen M
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113375
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113375
Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term.
Ducza E, Csányi A, Szőke É, Pohóczky K, Hajagos-Tóth J, Kothencz A, Tiszai Z, Gáspár R
Heliyon 2019 Oct;5(10):e02697
Heliyon 2019 Oct;5(10):e02697
The mechanosensitive ion channel TRPV4 is a regulator of lung development and pulmonary vasculature stabilization.
Morgan JT, Stewart WG, McKee RA, Gleghorn JP
Cellular and molecular bioengineering 2018 Oct;11(5):309-320
Cellular and molecular bioengineering 2018 Oct;11(5):309-320
Expressions of TRPVs in the cholesteatoma epithelium.
Do BH, Koizumi H, Ohbuchi T, Kawaguchi R, Suzuki H
Acta oto-laryngologica 2017 Oct;137(10):1039-1045
Acta oto-laryngologica 2017 Oct;137(10):1039-1045
Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.
Ahmad F, Chung YW, Tang Y, Hockman SC, Liu S, Khan Y, Huo K, Billings E, Amar MJ, Remaley AT, Manganiello VC
Scientific reports 2016 Jun 20;6:28056
Scientific reports 2016 Jun 20;6:28056
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 20987-1-AP(TRPV4 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TRPV4 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human TRPV4. This antibody recognizes human,mouse,rat antigen. The TRPV4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.