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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunohistochemistry [5]
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- Product number
- MA5-24649 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Laminin alpha-5 Monoclonal Antibody (CL3118)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: LNLSSIILDV NQDRLTQRAI EASNAYSRIL QAVQAAEDAA GQALQQADHT WATVVRQGLV DRAQQLLANS TALEEAMLQE QQRLGLVWAA L Binds to an epitope located within the peptide sequence RQGLVDRAQQ as determined by overlapping synthetic peptides.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- CL3118
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references The microvascular extracellular matrix in brains with Alzheimer's disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA).
Damodarasamy M, Vernon RB, Pathan JL, Keene CD, Day AJ, Banks WA, Reed MJ
Fluids and barriers of the CNS 2020 Sep 29;17(1):60
Fluids and barriers of the CNS 2020 Sep 29;17(1):60
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Laminin alpha-5 in human placenta using Laminin alpha-5 Monoclonal Antibody (CL3118) (Product # MA5-24649) shows moderate positivity in basement membrane of trophoblastic cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Laminin alpha-5 in human kidney using Laminin alpha-5 Monoclonal Antibody (CL3118) (Product # MA5-24649) shows strong membranous positivity in glomeruli, as well as in basement membrane of renal tubules.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Laminin alpha-5 in human colon using Laminin alpha-5 Monoclonal Antibody (CL3118) (Product # MA5-24649) shows moderate positivity in basement membrane of glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Laminin alpha-5 in human lymph node using Laminin alpha-5 Monoclonal Antibody (CL3118) (Product # MA5-24649) shows no positivity in lymphoid cells as expected.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of Laminin alpha-5 in human placenta and lymph node tissues using Laminin alpha-5 Monoclonal Antibody (CL3118) (Product # MA5-24649). Corresponding LAMA5 RNA-seq data are presented for the same tissues.
