Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- RA0248 - Provider product page

- Provider
- Oursmab
- Product name
- Freneslerbart (Biosimilar Reference Antibody) (Fel d 1)
- Antibody type
- Monoclonal
- Description
- Freneslerbart is an investigational, immunoglobulin G4 kappa (IgG4¦Ê) monoclonal antibody developed for the treatment or prevention of allergic reactions to cats. It functions as a targeted allergen-neutralizing therapy. Freneslerbart is designed to specifically bind with high affinity to Fel d 1 (Felis domesticus allergen 1), the major allergenic protein found in cat saliva, dander, and sebaceous glands. By binding to and neutralizing Fel d 1 in the environment (e.g., on airborne particles) or potentially within the body, the antibody aims to prevent the allergen from interacting with allergen-specific immunoglobulin E (IgE) on mast cells and basophils. This blockade inhibits the subsequent degranulation and release of inflammatory mediators (like histamine) that cause allergic symptoms, such as rhinitis, conjunctivitis, and asthma.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100 ¦Ìg,1 mg,5 mg-500,10 mg,25 mg,50 mg,146 mg
- Concentration
- Bottled at the concentration indicated on the vial.
- Storage
- Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
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Supportive validation
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- Oursmab (provider)
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- Experimental details
- Freneslerbart (Biosimilar Reference Antibody) (Fel d 1)-RA0248-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.