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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Western blot [1]
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- Product number
- BS3237 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS3237, RRID:AB_1663688
- Product name
- TG1019 (R251) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 220-270 of Human TG1019.
- Description
- TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a GÏ« i/o protein-coupled receptor. Signals from TG1019 are transduced via a GÏ« i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of TG1019 (R251) pAb at 1:500 dilutionLane1:A549 whole cell lysateLane2:Raw264.7 whole cell lysateLane3:PC12 whole cell lysate
