Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- HPA042309 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA042309, RRID:AB_10796575
- Product name
- Anti-AIFM2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human AIFM2, Gene description: apoptosis-inducing factor, mitochondrion-associated, 2, Alternative Gene Names: AMID, FLJ14497, PRG3, Validated applications: IHC, WB, Uniprot ID: Q9BRQ8, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references GPX4 and FSP1 Expression in Lung Adenocarcinoma: Prognostic Implications and Ferroptosis-Based Therapeutic Strategies
Mitochondrial regulation of GPX4 inhibition–mediated ferroptosis in acute myeloid leukemia
Histone acetyltransferase P300 deficiency promotes ferroptosis of vascular smooth muscle cells by activating the HIF-1α/HMOX1 axis.
Takahara H, Kanazawa T, Oshita H, Tomita Y, Hananoi Y, Ishibashi S, Ikeda M, Furukawa A, Kinoshita M, Yamamoto K, Kato Y, Ishibashi H, Okubo K, Kurata M, Kitagawa M, Ohashi K, Yamamoto K
Cancers 2024;16(22):3888
Cancers 2024;16(22):3888
Mitochondrial regulation of GPX4 inhibition–mediated ferroptosis in acute myeloid leukemia
Akiyama H, Zhao R, Ostermann L, Li Z, Tcheng M, Yazdani S, Moayed A, Pryor M, Slngh S, Baran N, Ayoub E, Nishida Y, Mak P, Ruvolo V, Carter B, Schimmer A, Andreeff M, Ishizawa J
Leukemia 2023;38(4):729-740
Leukemia 2023;38(4):729-740
Histone acetyltransferase P300 deficiency promotes ferroptosis of vascular smooth muscle cells by activating the HIF-1α/HMOX1 axis.
Shi J, Wang QH, Wei X, Huo B, Ye JN, Yi X, Feng X, Fang ZM, Jiang DS, Ma MJ
Molecular medicine (Cambridge, Mass.) 2023 Jul 6;29(1):91
Molecular medicine (Cambridge, Mass.) 2023 Jul 6;29(1):91
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and AIFM2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY403212).
- Sample type
- Human
- Protocol
- Protocol