Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations [0]
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- Product number
- MAB13501 - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Mouse/Bovine Integrin alpha 6/CD49f Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human, mouse, and bovine Integrin alpha 6/CD49f. Recognizes an epitope in the extracellular domain of the Integrin alpha 6 subunit.
- Reactivity
- Human, Mouse, Bovine
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- GoH3
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Phenotypic Analysis of BrdU Label-Retaining Cells during the Maturation of Conducting Airway Epithelium in a Porcine Lung.
Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signaling.
RANK Signaling Blockade Reduces Breast Cancer Recurrence by Inducing Tumor Cell Differentiation.
Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma.
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
α6-Integrin is required for the adhesion and vasculogenic potential of hemangioma stem cells.
Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins.
Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.
A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.
CD98hc (SLC3A2) regulation of skin homeostasis wanes with age.
Dedifferentiated follicular granulosa cells derived from pig ovary can transdifferentiate into osteoblasts.
Transcriptional activation of p53 by Pitx1.
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
Jia Y, You X, Ma N, Li H, Liu G, Wang Y, Xue J, Shi J, Wei J, Li Y, Yang J, Liu X
Stem cells international 2019;2019:7043890
Stem cells international 2019;2019:7043890
Dynamic blebbing: A bottleneck to human embryonic stem cell culture that can be overcome by Laminin-Integrin signaling.
Weng NJ, Cheung C, Talbot P
Stem cell research 2018 Dec;33:233-246
Stem cell research 2018 Dec;33:233-246
RANK Signaling Blockade Reduces Breast Cancer Recurrence by Inducing Tumor Cell Differentiation.
Yoldi G, Pellegrini P, Trinidad EM, Cordero A, Gomez-Miragaya J, Serra-Musach J, Dougall WC, Muñoz P, Pujana MA, Planelles L, González-Suárez E
Cancer research 2016 Oct 1;76(19):5857-5869
Cancer research 2016 Oct 1;76(19):5857-5869
Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma.
Unruh D, Ünlü B, Lewis CS, Qi X, Chu Z, Sturm R, Keil R, Ahmad SA, Sovershaev T, Adam M, Van Dreden P, Woodhams BJ, Ramchandani D, Weber GF, Rak JW, Wolberg AS, Mackman N, Versteeg HH, Bogdanov VY
Oncotarget 2016 May 3;7(18):25264-75
Oncotarget 2016 May 3;7(18):25264-75
Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
Seano G, Chiaverina G, Gagliardi PA, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain RK, Serini G, Bussolino F, Primo L
Nature cell biology 2014 Oct;16(10):931-41, 1-8
Nature cell biology 2014 Oct;16(10):931-41, 1-8
α6-Integrin is required for the adhesion and vasculogenic potential of hemangioma stem cells.
Smadja DM, Guerin CL, Boscolo E, Bieche I, Mulliken JB, Bischoff J
Stem cells (Dayton, Ohio) 2014 Mar;32(3):684-93
Stem cells (Dayton, Ohio) 2014 Mar;32(3):684-93
Monoclonal antibodies to human laminin α4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of α6β1 integrin and MCAM to α4-laminins.
Ishikawa T, Wondimu Z, Oikawa Y, Ingerpuu S, Virtanen I, Patarroyo M
Matrix biology : journal of the International Society for Matrix Biology 2014 Jun;36:5-14
Matrix biology : journal of the International Society for Matrix Biology 2014 Jun;36:5-14
Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.
Samarelli AV, Riccitelli E, Bizzozero L, Silveira TN, Seano G, Pergolizzi M, Vitagliano G, Cascone I, Carpentier G, Bottos A, Primo L, Bussolino F, Arese M
The Journal of biological chemistry 2014 Jul 11;289(28):19466-76
The Journal of biological chemistry 2014 Jul 11;289(28):19466-76
A novel multistep mechanism for initial lymphangiogenesis in mouse embryos based on ultramicroscopy.
Hägerling R, Pollmann C, Andreas M, Schmidt C, Nurmi H, Adams RH, Alitalo K, Andresen V, Schulte-Merker S, Kiefer F
The EMBO journal 2013 Mar 6;32(5):629-44
The EMBO journal 2013 Mar 6;32(5):629-44
CD98hc (SLC3A2) regulation of skin homeostasis wanes with age.
Boulter E, Estrach S, Errante A, Pons C, Cailleteau L, Tissot F, Meneguzzi G, Féral CC
The Journal of experimental medicine 2013 Jan 14;210(1):173-90
The Journal of experimental medicine 2013 Jan 14;210(1):173-90
Dedifferentiated follicular granulosa cells derived from pig ovary can transdifferentiate into osteoblasts.
Oki Y, Ono H, Motohashi T, Sugiura N, Nobusue H, Kano K
The Biochemical journal 2012 Oct 15;447(2):239-48
The Biochemical journal 2012 Oct 15;447(2):239-48
Transcriptional activation of p53 by Pitx1.
Liu DX, Lobie PE
Cell death and differentiation 2007 Nov;14(11):1893-907
Cell death and differentiation 2007 Nov;14(11):1893-907
Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli.
Eto DS, Jones TA, Sundsbak JL, Mulvey MA
PLoS pathogens 2007 Jul;3(7):e100
PLoS pathogens 2007 Jul;3(7):e100
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