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Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF528 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal CCL24/Eotaxin-2/MPIF-2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects CCL24/Eotaxin-2/MPIF-2 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human Eotaxin-2 is observed, and less than 1% cross-reactivity with recombinant mouse Eotaxin is observed.
- Reactivity
- Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus.
Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart.
Comprehensive assessment of chemokine expression profiles by flow cytometry.
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Kannan Y, Entwistle LJ, Pelly VS, Perez-Lloret J, Walker AW, Ley SC, Wilson MS
PLoS pathogens 2017 Jul;13(7):e1006536
PLoS pathogens 2017 Jul;13(7):e1006536
Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart.
Diny NL, Hou X, Barin JG, Chen G, Talor MV, Schaub J, Russell SD, Klingel K, Rose NR, Čiháková D
European journal of immunology 2016 Dec;46(12):2749-2760
European journal of immunology 2016 Dec;46(12):2749-2760
Comprehensive assessment of chemokine expression profiles by flow cytometry.
Eberlein J, Nguyen TT, Victorino F, Golden-Mason L, Rosen HR, Homann D
The Journal of clinical investigation 2010 Mar;120(3):907-23
The Journal of clinical investigation 2010 Mar;120(3):907-23
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J
Nature 2009 Jul 9;460(7252):225-30
Nature 2009 Jul 9;460(7252):225-30
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chemotaxis Induced by CCL24/Eotaxin‑2 and Neutralization by Mouse CCL24/Eotaxin‑2 Antibody. Chemotaxis Induced by CCL24/Eotaxin‑2 and Neutralization by Mouse CCL24/Eotaxin‑2 Antibody.
